Navigation Links
Late Breaking Data Released at ADA Showed that the Investigational,Use of Januvia and Metformin as Initial Combination Therapy,Provided Significant Glucose Lowering Efficacy over 54 Weeks in,Patients with Type 2 Diabetes

. There is no experience with doses above 800 mg in humans. In the event of an overdose, it is reasonable to employ the usual supportive measures, e.g., remove unabsorbed material from the gastrointestinal tract, employ clinical monitoring (including obtaining an electrocardiogram), and institute supportive therapy as dictated by the patient's clinical status. Sitagliptin is modestly dialyzable. In clinical studies, approximately 13.5% of the dose was removed over a 3- to 4-hour hemodialysis session. Prolonged hemodialysis may be considered if clinically appropriate. It is not known if sitagliptin is dialyzable by peritoneal dialysis. 11 DESCRIPTION JANUVIA Tablets contain sitagliptin phosphate, an orally-active inhibitor of the dipeptidyl peptidase-4 (DPP-4) enzyme. Sitagliptin phosphate is described chemically as 7-((3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl)-5,6,7,8- tetrahydro-3- (trifluoromethyl)-1,2,4-triazolo(4,3-a)pyrazine phosphate (1:1) monohydrate. The empirical formula is C16H15F6N5O-H3PO4-H2O and the molecular weight is 523.32. The structural formula is: (OBJECT OMITTED) Sitagliptin phosphate is a white to off-white, crystalline, non-hygroscopic powder. It is soluble in water and N,N-dimethyl formamide; slightly soluble in methanol; very slightly soluble in ethanol, acetone, and acetonitrile; and insoluble in isopropanol and isopropyl acetate. Each film-coated tablet of JANUVIA contains 32.13, 64.25, or 128.5 mg of sitagliptin phosphate monohydrate, which is equivalent to 25, 50, or 100 mg, respectively, of free base and the following inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, and sodium stearyl fumarate. In addition, the film coating contains the following inactive ingredients: polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, red iron oxide, and yellow iron oxide.
'"/>




Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32

Related medicine technology :

1. VeroScience Late-Breaking Abstract on Cycloset (A Quick Release Formulation of Bromocriptine Mesylate) Accepted for Poster Presentation at American Diabetes Association 67th Scientific Sessions
2. Pilot Phase 3 Results of NovaCardias KW-3902 for Acute Congestive Heart Failure Presented at Late-Breaking Session of Heart Failure Congress 2007
3. Breaking Multi-Center Study: Masimo SET Pulse Oximetry Technology Shown to Significantly Lower Instances of Severe Retinopathy of Prematurity in Extremely Low Birth Weight Infants
4. Bentley Late Breaking Abstract Accepted for Poster Presentation at American Diabetes Association Scientific Sessions
5. Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR Annual Meeting Late-Breaking Clinical Trials Session
6. Everest Data on Short- and Long-Term Use of Otsukas Investigational Novel Treatment, Tolvaptan, Published in Journal of the American Medical Association and Featured in ACCs Late Breaking Clinical Trials
7. Lupus Foundation of America Statement on Results for Clinical Study of CellCept Released by Aspreva Pharmaceutical Company
8. An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes
9. Amlodipine and Olmesartan Study Results Released;Late Breaker Presented at American Society of Hypertension Twenty-Second Annual Scientific Meeting (ASH 2007)
10. Amlodipine and Olmesartan Study Results Released; Late Breaker Presented at American Society of Hypertension Twenty-Second Annual Scientific Meeting (ASH 2007)
11. New Anti-Rejection Medication 6-Month Results for Heart Transplant Recipients to Be Released at International Heart and Lung Transplant Meeting
Post Your Comments:
(Date:7/23/2014)... -- On Tuesday, July 1, 2014, Eclipse ... 116 th Judicial District Court in ... USA, LLC ("Defendant") for Tortious Interference ... false and misleading actions, fraud, fraud-in-the-inducement, business interference, ... libel, disparagement, defamation, misrepresentation, and violating the false/deceptive ...
(Date:7/23/2014)... -- Creekridge Capital, an independent vendor-focused finance company, ... far in 2014 to their portfolio of contractual ... both the healthcare and technology industries. They range ... companies. Each of these new vendors take advantage ... standard leasing products, subscription solutions, a dedicated revolving ...
(Date:7/23/2014)... 2014  Mezzion Pharma Co. Ltd., announced that it ... of udenafil to treat adolescents who have undergone the ... clinical program will follow protocols developed by a subcommittee ... (PHN), a multi-center clinical research network funded by the ... National Institutes of Health (NIH). The ...
Breaking Medicine Technology:Creekridge Capital Signs Several New Vendor Partners 2Mezzion Pharma Initiates Clinical Development Program To Evaluate Udenafil In Adolescents With Single Ventricle Heart Defects 2
... , HOLMDEL, N.J., Nov. 24 Sparta Systems, Inc., ... enterprise quality and compliance solutions, today announced that SSL International ... company for globally recognized brands such as Durex and Scholl, ... The company is now leveraging the TrackWise system to harmonize ...
... , MISSISSAUGA, Ontario, Nov. 24 CardioGenics Holdings Inc. (OTC ... the immunoassay segment of the IVD testing market, reports that ... phase of the commercialization of CardioGenics, proprietary silver coated paramagnetic ... Chimie that was executed earlier this year, CardioGenics supplied Merck ...
Cached Medicine Technology:SSL International plc Embraces TrackWise(R) Software for Global Quality and Compliance Efforts 2SSL International plc Embraces TrackWise(R) Software for Global Quality and Compliance Efforts 3CardioGenics Provides Update on Agreement with Merck Chimie for Its Silver Coated Paramagnetic Beads 2CardioGenics Provides Update on Agreement with Merck Chimie for Its Silver Coated Paramagnetic Beads 3
(Date:7/23/2014)... 2014 Texas Physical Therapy Specialists (TexPTS) ... their Westlake, Westgate, Liberty Hill, Parmer, Balcones, and Georgetown ... of Orthopaedic Certified Specialist (OCS) or ... PT, DPT, OCS, Tony Lauretta, PT, DPT, OCS, Jason ... Joseph Leech, PT, DPT, OCS, and Mary Grimberg, PT, ...
(Date:7/23/2014)... 2014 A therapy combining salmon fibrin injections into ... into the brain restored voluntary motor function impaired by ... Center have found. , In a study on rodents, ... turning back the developmental clock in a molecular pathway ... and providing a scaffold so that neuronal axons at ...
(Date:7/23/2014)... 23, 2014 The North American market was ... to grow at a CAGR of 10.79%, to reach $1,801.1 ... North America. , The North American Bromine Market report defines ... forecast of revenue. , Browse through the TOC of the ... the in-depth analysis provided. This also provides a glimpse of ...
(Date:7/23/2014)... 2014 Absolute PhysioCare and Sports Rehab, ... of its custom orthotics and gait scan analysis that ... in order to restore normal body balance. This treatment ... fatigue and pain. In addition, Custom orthotics provides shock ... foot, resulting in relief and greater comfort while walking, ...
(Date:7/23/2014)... latest blog post, Best Drug Rehabilitation , which offers ... a stay in rehab can make a big difference in ... a topic that is quickly becoming among the most important ... The Best Drug Rehabilitation blog post on opiate abuse facts ... why they’re considered “the mother of all Schedule II drugs” ...
Breaking Medicine News(10 mins):Health News:Texas Physical Therapy Specialists Congratulates New Board Certified Specialists 2Health News:Texas Physical Therapy Specialists Congratulates New Board Certified Specialists 3Health News:Gene inhibitor, salmon fibrin restore function lost in spinal cord injury 2Health News:North America Bromine Market is Expected to Reach $1801.1 million in 2018 - New Report by MicroMarket Monitor 2Health News:North America Bromine Market is Expected to Reach $1801.1 million in 2018 - New Report by MicroMarket Monitor 3Health News:North America Bromine Market is Expected to Reach $1801.1 million in 2018 - New Report by MicroMarket Monitor 4Health News:Custom Orthotics at Burnaby PhysioCare Now Correct Foot Abnormalities 2Health News:Latest Best Drug Rehabilitation Blog Post Focuses on Opiate Abuse Facts 2
... are neglected before their second birthday display higher levels ... to a University of North Carolina at Chapel Hill ... , Early child neglect may be as important as ... accounts for nearly two-thirds of all child maltreatment cases ...
... college far less than thought , , SUNDAY, April 6 (HealthDay ... realistically the "Freshman 5." , A new study of 36 ... of 1.9 pounds during the first semester of the first ... for the entire year. Men gained an average of 5.4 ...
... 6, 2008 Pitt County Memorial,Hospital (PCMH) ... reduction in the rate of ventilator-associated pneumonia ... the surgical,intensive care unit (SICU) with the ... These data were presented today as a ...
... holiday, expert says , , SUNDAY, April 6 (HealthDay News) -- ... and fly off to holiday destinations. But, there are a ... a safe flight, says the American Geriatrics Society. , ... upcoming plane travel," Dr. Sharon A. Brangman, an AGS member, ...
... most critical characteristics for any diagnostic tool. A new ... performed on computer or via computer simulation) saliva diagnostic ... of the American Association for Dental Research in Dallas, ... life, the SKB will serve as a catalyst for ...
... chemicals targeting disease , , FRIDAY, April 4 (HealthDay ... has been developed by researchers at the University of ... anti-cancer drugs inside tiny pores and releases the drugs ... first light-powered nanomachine able to operate inside a living ...
Cached Medicine News:Health News:Early neglect predicts aggressive behavior in children 2Health News:'Freshman 15' Theory Takes a Pounding 2Health News:'Freshman 15' Theory Takes a Pounding 3Health News:Preliminary Data From Pitt County Memorial Hospital Study Show Benefit of Active Surveillance on Reducing MRSA VAP Rates in Surgical ICU 2Health News:Preliminary Data From Pitt County Memorial Hospital Study Show Benefit of Active Surveillance on Reducing MRSA VAP Rates in Surgical ICU 3Health News:Travel Tips for Seniors 2Health News:Salivary diagnostics, the 'magic mirror' to your health ... at your personal computer 2Health News:'Nanomachine' Releases Anticancer Drugs Inside Cells 2
... drive system which eliminates many of ... out. There are no motor brushes, ... drive belts - resulting in a ... carry weights up to 400 pounds. ...
... The Quinton Q-Stress Cardiac Stress ... baseline wander and muscle artifact ... second to provide the highest ... Leads can be displayed in ...
... ECT WS 2000 is designed to monitor, ... cardiovascular provocative tests, (stress-testing). The system can organize ... and provide them for a quick review and ... ,The recorded ECG is transmitted via a small ...
... compact BioStress 2000 is a software driven, ... testing system. The BioStress 2000 program is ... viewing, permanent ECG strorage and retrieval and ... printer. BioStress 2000 allows a wide range ...
Medicine Products: