Navigation Links
Late Breaking Data Released at ADA Showed that the Investigational,Use of Januvia and Metformin as Initial Combination Therapy,Provided Significant Glucose Lowering Efficacy over 54 Weeks in,Patients with Type 2 Diabetes

or behavioral toxicity was observed in offspring of rats. Placental transfer of sitagliptin administered to pregnant rats was approximately 45% at 2 hours and 80% at 24 hours postdose. Placental transfer of sitagliptin administered to pregnant rabbits was approximately 66% at 2 hours and 30% at 24 hours. 8.3 Nursing Mothers Sitagliptin is secreted in the milk of lactating rats at a milk to plasma ratio of 4:1. It is not known whether sitagliptin is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when JANUVIA is administered to a nursing woman. 8.4 Pediatric Use Safety and effectiveness of JANUVIA in pediatric patients have not been established. 8.5 Geriatric Use Of the total number of subjects (N=3884) in clinical safety and efficacy studies of JANUVIA, 725 patients were 65 years and over, while 61 patients were 75 years and over. No overall differences in safety or effectiveness were observed between subjects 65 years and over and younger subjects. While this and other reported clinical experience have not identified differences in responses between the elderly and younger patients, greater sensitivity of some older individuals cannot be ruled out. This drug is known to be substantially excreted by the kidney. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection in the elderly, and it may be useful to assess renal function in these patients prior to initiating dosing and periodically thereafter (see Dosage and Administration (2.2); Clinical Pharmacology (12.3)). 10 OVERDOSAGE During controlled clinical trials in healthy subjects, single doses of up to 800 mg JANUVIA were administered. Maximal mean increases in QTc of 8.0 msec were observed in one study at a dose of 800 mg JANUVIA, a mean effect that is not considered clinically important (see Clinical Pharmacology (12.2))
'"/>




Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32

Related medicine technology :

1. VeroScience Late-Breaking Abstract on Cycloset (A Quick Release Formulation of Bromocriptine Mesylate) Accepted for Poster Presentation at American Diabetes Association 67th Scientific Sessions
2. Pilot Phase 3 Results of NovaCardias KW-3902 for Acute Congestive Heart Failure Presented at Late-Breaking Session of Heart Failure Congress 2007
3. Breaking Multi-Center Study: Masimo SET Pulse Oximetry Technology Shown to Significantly Lower Instances of Severe Retinopathy of Prematurity in Extremely Low Birth Weight Infants
4. Bentley Late Breaking Abstract Accepted for Poster Presentation at American Diabetes Association Scientific Sessions
5. Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR Annual Meeting Late-Breaking Clinical Trials Session
6. Everest Data on Short- and Long-Term Use of Otsukas Investigational Novel Treatment, Tolvaptan, Published in Journal of the American Medical Association and Featured in ACCs Late Breaking Clinical Trials
7. Lupus Foundation of America Statement on Results for Clinical Study of CellCept Released by Aspreva Pharmaceutical Company
8. An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes
9. Amlodipine and Olmesartan Study Results Released;Late Breaker Presented at American Society of Hypertension Twenty-Second Annual Scientific Meeting (ASH 2007)
10. Amlodipine and Olmesartan Study Results Released; Late Breaker Presented at American Society of Hypertension Twenty-Second Annual Scientific Meeting (ASH 2007)
11. New Anti-Rejection Medication 6-Month Results for Heart Transplant Recipients to Be Released at International Heart and Lung Transplant Meeting
Post Your Comments:
(Date:8/29/2015)... y LONDRES, August 29, 2015 ... para los sistemas de imagen por Ultrasonidos ... Ecografía, tiempos de examen rápidos y un flujo de ... confianza diagnóstica en el proceso de detección de Cardiopatías ... PHIA) ha anunciado hoy el lanzamiento europeo de ...
(Date:8/28/2015)... 2015  With the heroin epidemic in ... Jacksonville -based Lakeview Health drug and alcohol ... to explain why fentanyl is causing a new wave ... times more potent than pharmaceutical grade heroin and often ... risk of death skyrockets. "Fentanyl can be ...
(Date:8/28/2015)... Aug. 28, 2015  Delays in the launch ... slow down the decision-making process, resulting in missed ... critical for biopharmaceutical companies to develop a tactical ... for quicker and more meaningful insights. ... LLC, nearly three-quarters of benchmarked study participants use ...
Breaking Medicine Technology:Philips presenta HeartModel A.I en el Congreso ESC 2015 2Philips presenta HeartModel A.I en el Congreso ESC 2015 3Philips presenta HeartModel A.I en el Congreso ESC 2015 4Philips presenta HeartModel A.I en el Congreso ESC 2015 5Lakeview Health's Dr. Philip Hemphill Explains Why Heroin Addicts Are Now Dying of Fentanyl Overdoses 2Expediting the Pharmaceutical Market Research Process for Faster Insights 2
... Therapeutics (NYSE Amex: CXM ) today ... a topically applied formulated collagen wound management gel ... factor (PDGF) locally at the wound site.  This ... essential role in the wound healing process. ...
... Prime Therapeutics (Prime), a thought leader in ... awarded full Pharmacy Benefit Management (PBM) accreditation from ... that establishes quality standards for the health care ... URAC accreditation in 2007, and has also achieved ...
Cached Medicine Technology:Cardium Announces New Research Findings: Excellagen Product Candidate Activates Platelet Release of PDGF, an Important Growth Factor Fundamental to the Wound Healing Process 2Cardium Announces New Research Findings: Excellagen Product Candidate Activates Platelet Release of PDGF, an Important Growth Factor Fundamental to the Wound Healing Process 3Cardium Announces New Research Findings: Excellagen Product Candidate Activates Platelet Release of PDGF, an Important Growth Factor Fundamental to the Wound Healing Process 4Cardium Announces New Research Findings: Excellagen Product Candidate Activates Platelet Release of PDGF, an Important Growth Factor Fundamental to the Wound Healing Process 5Cardium Announces New Research Findings: Excellagen Product Candidate Activates Platelet Release of PDGF, an Important Growth Factor Fundamental to the Wound Healing Process 6Cardium Announces New Research Findings: Excellagen Product Candidate Activates Platelet Release of PDGF, an Important Growth Factor Fundamental to the Wound Healing Process 7Prime Therapeutics Announces URAC Accreditation 2
(Date:8/29/2015)... (PRWEB) , ... August 29, 2015 , ... ... to insufficient scrotal support and protection against dribbled urine and sweat. "In order ... Manhasset Hills, N.Y. , The EASY ACCESS DRYNESS ENHANCED MEN'S UNDERGARMENT provides optimal ...
(Date:8/29/2015)... Aliso Viejo, CA (PRWEB) , ... August 29, 2015 , ... ... Cut Pro X . Each preset contains 15 seconds of unique footage that users ... presets that rise, fall, zoom, attract and more. Users can customize color, brightness, scale, ...
(Date:8/28/2015)... ... 29, 2015 , ... Rio Salado College joined nine educational institutions ... part of the EDUCAUSE - Next Generation Learning Challenges 2015 Breakthrough Models Incubator funded ... Breakthrough Models Incubator hosted by EDUCAUSE and NGLC, which is designed to ...
(Date:8/28/2015)... Angeles, CA (PRWEB) , ... August 28, 2015 , ... ... endless journey that local pizza maker Paul LaRocco has gone through to open a ... city approval and permitting process tends to take several months, but the current process, ...
(Date:8/28/2015)... ... 2015 , ... The 6th Annual Survivor in the City, Chicago silent ... another accolade to its cadre of widespread support—an official letter of support and gratitude ... the medical community and the University of Illinois at Chicago’s Department of Neurosurgery, the ...
Breaking Medicine News(10 mins):Health News:Modified Men’s Underwear Promote More Comfort and Hygiene - Designed by InventHelp Client (LGI-1968) 2Health News:FCPX Effects Developer, Pixel Film Studios, Releases ProDrop Particles. 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 2Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 3Health News:Rio Salado College Joins 9 Educational Leaders to Reinvent Higher Learning 4Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 3
... percent of US adults have never had sex in their ... case of Mexican-Americans, according to an official survey out on ... years have had sex, with the age group 20-29 having ... and Prevention (CDC) said in a report. ,Eighty-eight percent ...
... is taking heavy toll of the US. Time something is ... Where does one cross the line? These are always problematic ... ,Unrestrained hedonism could pose serious public health threats, observers in ... of U.S. adults are virgins and a fifth have tried ...
... the European Union (EU) Parliament's resolution to ban mercury trade ... do likewise. ,Toxics Link and other green ... group had called upon governments across the world to ban ... (UNEP) in February. ,In one of its ...
... State University professors, Volodymyr Tarabara and Tom Voice, are ... . ,Tarabara and Voice are leading an international ... research universities, two research centers in France, and three ... technologies for the project. ,With the biggest ...
... her growing years that doctors thought she had brain tumour . ... eight till she was 13, when her parents separated. ... stress of her parents troubled married life. ,The 19-year-old ... was all in her head, and though the memories werent great, ...
... will be traveling next week and during July will ... 18-year old Nicholas Tan Xue-Wei, who will soon depart ... research paper at The 2007 World Congress in ... 25 to 28, in Las Vegas. ,Before ...
Cached Medicine News:Health News:US Observers Concerned Over Increasingly Permissive Atmosphere 2Health News:Two MSU Professors Spearhead International Water Project 2Health News:Two MSU Professors Spearhead International Water Project 3Health News:Singaporean Student to Present Stem Cell Research Paper at Conferences in US, UK 2
... Bard. The Hernia Repair CompanySM is pleased ... hernia repair - Bard Composix E/X mesh.,When ... it was the first ventral hernia repair ... Bard polypropylene mesh and ePTFE, in one ...
... Kugel Patch, which is constructed of a double ... a positioning pocket, which is used to guide ... other side is a barrier of ePTFE. The ... which causes the patch to spring open and ...
... introduction in 1958, Bard mesh has become ... are compared. Bard mesh was used by ... the "tension-free" hernia repair many years ago. ... and ideal" substance for permanent reinforcement of ...
... Bard Visilex mesh is the ... laparoscopic hernia repair. Visilex mesh directly ... laparoscopic procedures. More specifically, it delivers ... a flat profile after insertion through ...
Medicine Products: