Navigation Links
Large Geographic Differences in EpiPen Prescriptions in the U.S.,,From the Journal of Allergy and Clinical Immunology

MILWAUKEE, July 11, 2007 /PRNewswire/ -- A new study suggests strong variation in the occurrence of anaphylaxis between the northern and southern U.S. Anaphylaxis is a severe allergic reaction that can be fatal without treatment with epinephrine. The striking north-south differences in EpiPen prescribing, a marker of anaphylaxis risk, currently are without explanation. The investigators hypothesize, however, that low levels of vitamin D from lack of sunshine, may play a role and that this hypothesis requires further investigation.

The study, "Regional differences in EpiPen prescriptions in the United States: The potential role of vitamin D," can be found in the July 2007 issue of the Journal of Allergy and Clinical Immunology (JACI), the peer-reviewed journal of the American Academy of Allergy, Asthma and Immunology (AAAAI).

Carlos A. Camargo, MD, DrPH, FAAAAI, and colleagues obtained data on EpiPen prescriptions in 2004 for all 50 states and Washington, D.C. They used state populations to calculate the average number of prescriptions written per person.

Researchers found that on average, there were 5.71 EpiPens prescribed per 1000 persons in the U.S. The highest number of prescriptions per 1000 persons was in Massachusetts with 11.8. Hawaii had the lowest with 2.7 prescriptions per 1000 persons.

The team also found a regional difference in the number of prescriptions. New England had the highest values with 8 to 12 EpiPen prescriptions per 1000 persons, and southern states had only 3 prescriptions per 1000 persons. These findings persisted even after adjusting for differences in population characteristics, healthcare data and other factors.

The explanation for the strong variation between northern states and southern states is not clear. The investigators note, however, that southern states have a warmer climate and more year-round sunlight and that their findings support rec ent speculation about a link between low Vitamin D levels from less sunlight, and higher incidence of respiratory and allergic diseases. This study suggests that perhaps more year-round sunshine in the south led to higher Vitamin D levels and could explain the north-south difference in the incidence of respiratory and allergic disease.

The AAAAI represents allergists, asthma specialists, clinical immunologists, allied health professionals and others with a special interest in the research and treatment of allergic disease. Allergy/immunology specialists are pediatric or internal medicine physicians who have elected an additional two years of training to become specialized in the treatment of asthma, allergy and immunologic disease. Established in 1943, the AAAAI has more than 6,500 members in the United States, Canada and 60 other countries. The AAAAI serves as an advocate to the public by providing educational information through its Web site at http://www.aaaai.org.

CONTACT: Natalie Lemke, , or Amber Johnson,, +1-414-272-6071, both of the AAAAI nlemke@aaaai.org ajohnson@aaaai.org

Web site: http://www.aaaai.org/

Terms and conditions of use apply
Copyright © 2007 PR Newswire Association LLC. All rights reserved.
A United Business Media Company


'"/>




Related medicine technology :

1. Urinalysis Analyzers: Large Capabilities in Every Size Device
2. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
3. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
4. Largest National U.S. Healthcare Facility MRSA Study Reveals Infection Rates Eight Times Greater Than Previous Estimates
5. Newly Published Data from Large Study Support Cardiovascular Safety of Avandia (Rosiglitazone Maleate)
6. MedImmune Announces Positive Clinical Results at PAS Annual Meeting From Large Prospective Trial in Prevention of Serious RSV Disease
7. First Controlled Large-Scale Intervention Angiotensin Receptor Blocker (ARB) Trial in a Japanese Population, JIKEI HEART Study Demonstrates Significant Reduction in Blood Pressure and Protection of Organs with Valsartan
8. Large Study Shows that Presence of Neutralizing Antibodies Did Not Predict Clinical Response to Betaseron Treatment
9. Medical Journal Publishes First Large-Scale Survey Revealing Experiences of IPF Patients
10. Positive Aggrastat Results Featured in the Journal of the American College of Cardiology
11. Peer Reviewed Journal Article Indicates Repros Proellex Exhibits Potential for New Approach to the Treatment and Prevention of Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... Capricor Therapeutics, Inc. ... company focused on the discovery, development and commercialization ... in its ongoing randomized HOPE-Duchenne clinical trial (Halt ... its 24-patient target. Capricor expects the trial to ... 2016, and to report top line data from ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 ... Tomorrow,s Leaders Scholarship is any indication, the future is ... online at www.diabetesscholars.org by the Diabetes Scholars ... in the way of academic and community service excellence. ... program since 2012, and continues to advocate for people ...
(Date:6/23/2016)... 23, 2016 The vast majority of dialysis ... facility.  Treatments are usually 3 times a week, with ... including travel time, equipment preparation and wait time.  This ... grueling for patients who are elderly and frail.  Many ... and rehabilitation centers for some duration of time. ...
Breaking Medicine Technology:
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer ... they remain in the eye of the beholder, according to experts who offered insights ... American Journal of Managed Care. For the full issue, click here . , ...
(Date:6/26/2016)... California (PRWEB) , ... June 26, 2016 , ... Pixel ... Cut Pro X. , "Film editors can give their videos a whole new perspective ... Christina Austin - CEO of Pixel Film Studios. , ProSlice Levels contains over ...
(Date:6/26/2016)... Charlotte, NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind ... able to be personalized through a fitness app. The fitness app plans to fix the ... solutions currently only offer a one size fits all type program , They ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, ... work on several important health care topics including advance care planning, healthcare costs ...
(Date:6/25/2016)... FL (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial ... Plant City Observer , brings up a new, often overlooked aspect of head lice: the ... closing for fumigation is not a common occurrence, but a necessary one in the event ...
Breaking Medicine News(10 mins):