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Landmark Study Published in the New England Journal of Medicine,Shows Important Benefits of Eprodisate (KIACTA) Treatment for,Patients with Amyloid A (AA) Amyloidosis

ECUBLENS, SWITZERLAND, June 07, 2007 /PRNewswire-FirstCall/ - Neurochem (International) Limited (Neurochem), a wholly-owned subsidiary of Neurochem Inc. , announces that the New England Journal of Medicine (NEJM) published the results of the "Eprodisate For AA Amyloidosis Trial" (EFAAT), recognized as a landmark clinical trial in the search for a treatment of AA amyloidosis. The results of the Phase II/III clinical trial for eprodisate (KIACTA(TM)) demonstrate that this product candidate offers important clinical benefits to patients by reducing the progression of AA amyloidosis-associated renal disease. The results from the EFAAT have been submitted to the U.S. Food and Drug Administration, the European Medicines Agency and Swissmedic in support of applications for marketing approval of eprodisate (KIACTA(TM)) for the treatment of AA amyloidosis, a disease which remains today without a specific treatment.

The print issue of the publication will be available in the June 7, 2007 issue of the NEJM. The article entitled "Eprodisate for the Treatment of Renal Disease in AA Amyloidosis" is accessible online, and can be found at www.nejm.org under the "Current Issue" section of the Web site.

"These results show clinically important benefits for patients suffering from this disabling and potentially fatal disease," said Dr. Laura Dember, nephrologist and Associate Professor of Medicine, School of Medicine, and the lead author of the New England Journal of Medicine article reporting the results of the Phase II/III clinical trial for eprodisate (KIACTA(TM)). "Our treatment approach, up to this point, has been limited to controlling the inflammatory condition that underlies the development of AA amyloidosis. However, for many patients such efforts are unsuccessful and amyloid formation continues. KIACTA(TM) is the first product candidate designed to target
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