( to such differences includewhether the...)Landmark Findings From ECLIPSE Program Show Improved Control of,Perioperative Hypertension Reduces Risk of Death In Cardiac Surgery,Health

to such differences include whether the Company's products will advance in the clinical trials process on a timely basis or at all, whether clinical trial results will warrant submission of applications for regulatory approval, whether the Company will be able to obtain regulatory approvals, whether physicians, patients and other key decision makers will accept clinical trial results, and such other factors as are set forth in the risk factors detailed from time to time in the Company's periodic reports and registration statements filed with the Securities and Exchange Commission including, without limitation, the risk factors detailed in the Company's Annual Report on Form 10-K filed on March 1, 2007, which are incorporated herein by reference. The Company specifically disclaims any obligation to update these forward-looking statements.

    * Evaluation of CLevidipine In the Postoperative Treatment of Hypertension

      Assessing Safety Events


    ** Dr. Solomon Aronson is a paid consultant for The Medicines Company

CONTACT: Media - Jackie Krieger Biosector 2 +1-212-845-5612 Investors - Michael Mitchell Executive Director,Corporate Affairs The Medicines Company +1-973-656-1616 jkrieger@biosector2.com investor.relations@themedco.com

Web site: http://www.themedicinescompany.com/

Ticker Symbol: (:MDCO)

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