Navigation Links
Investigational Cancer Drug Pertuzumab Shows Promising Results in,Advanced Breast Cancer When Combined with Herceptin

increased quantities of the HER2 protein are present on the surface of the tumour cells. This is known as 'HER2-positivity.' High levels of HER2 are present in a particularly aggressive form of the disease which responds poorly to chemotherapy. Research shows that HER2-positivity affects approximately 20-30 percent of women with breast cancer.

About pertuzumab Pertuzumab is a humanized monoclonal antibody designed to bind to the HER2 receptor and inhibit the ability of HER2 to interact with other HER family members (HER1, HER2, HER3, and HER4) on the surface of cancer cells. The HER signaling pathway plays a role in the formation and growth of numerous cancers, and previous clinical trials of pertuzumab in a single agent setting had suggested clinical activity - including stable disease - in heavily pretreated patients with advanced ovarian and breast cancers. Genentech and Roche are evaluating pertuzumab in solid tumors (ovarian and breast cancers), and in combination with other therapies.

About Herceptin (trastuzumab) Herceptin is a humanised antibody, designed to target and block the function of HER2, a protein produced by a specific gene with cancer-causing potential. It has demonstrated efficacy in treating both early and advanced (metastatic) breast cancer. Given on its own as monotherapy as well as in combination with or following standard chemotherapy, Herceptin has been shown to improve response rates, disease-free survival and overall survival while maintaining quality of life in women with HER2-positive breast cancer.

Herceptin received approval for use in the European Union for advanced (metastatic) HER2-positive breast cancer in 2000 and for early HER2-positive breast cancer in 2006. In the advanced setting, Herceptin is now approved for use as a first-line therapy in combination with paclitaxel where anthracyclines are unsuitable, as first-line therapy in combination with docetaxel, and as a single agent in third-line therapy. In M
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
2. An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes
3. Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes
4. Investigational Study Demonstrated a Re-Establishment of Clinical Improvement with Orencia (Abatacept) in Children with Juvenile Idiopathic Arthritis upon Re-Introduction of Therapy
5. Mercks Investigational Migraine Treatment MK-0974 Significantly Improved Migraine Pain on Several Efficacy Measures in a Phase II Study
6. Data Demonstrated Metastatic Melanoma Response to Investigational Immunotherapy Ipilimumab
7. Investigational Drug Cediranib (AZD2171) Shows Promise in Patients With Recurrent Glioblastoma (GBM)
8. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
9. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
10. Shire Announces Positive Results of Studies With Guanfacine Extended Release, An Investigational Nonstimulant Medication Filed for the Treatment of ADHD in Children and Adolescents
11. Investigational Study Evaluates the Effectiveness of Aripiprazole in Adolescents With Schizophrenia
Post Your Comments:
(Date:8/29/2014)... , August 29, 2014 ... and collaboration software has announced a major new deal ... founded by renowned pathology expert, Dr. Marius Nap ... of the 26th European Congress of Pathology which is ... the ExCeL Arena, London where ...
(Date:8/28/2014)... -- Reportlinker.com announces that a new market research ... North America Aesthetic Lasers and Energy Devices Market ... North America Aesthetic Lasers and ... GlobalData,s new report, "North America Aesthetic Lasers ... key market data on the North America Aesthetic ...
(Date:8/28/2014)... NEW YORK , Aug. 28, 2014 /PRNewswire/ ... report is available in its catalogue: ... to 2020 http://www.reportlinker.com/p02343442/Germany-Aesthetic-Lasers-and-Energy-Devices-Market-Outlook-to-2020.html ... Market Outlook to 2020 Summary GlobalData,s ... Market Outlook to 2020", provides key market data ...
Breaking Medicine Technology:Pixcelldata Announces New Deal with Dutch Tele-Pathology Specialists eX-Path Ahead of ECP 2014 2North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 2North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 3North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 4North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 5North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 6North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 7North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 8North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 9North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 10North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 11North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 12North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 13North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 14North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 15North America Aesthetic Lasers and Energy Devices Market Outlook to 2020 16Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 2Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 3Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 4Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 5Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 6Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 7Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 8Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 9
... BROOK, N.J., March 28, 2011 Diopsys, Inc. has ... to help optometrists and ophthalmologists detect optic nerve disease, ... Glaucoma is the second leading cause of blindness in ... Prevent Blindness America, glaucoma is often called the "sneak ...
... 28, 2011 AmeriCares and AstraZeneca have teamed ... with chronic diseases throughout the United States. AstraZeneca ... medications to AmeriCares in support of its Domestic ... and medical supplies to a network of more ...
Cached Medicine Technology:New Vision Test Helps Detect Optic Nerve Diseases Including Glaucoma 2AmeriCares and AstraZeneca Work Together Delivering Critical Medicines to Help People Living with Chronic Diseases in the U.S. 2
(Date:8/29/2014)... Last week, the Fed reported an ... Industrial production rose to 0.4% while manufacturing output progressed to ... single largest boost since February this year. Capacity use has ... as well – an increase that could be attributed to ... 79.2% rate, which is a measure of slack across the ...
(Date:8/29/2014)... India (PRWEB) August 29, 2014 Ethane ... has recently launched a new service named HTML web ... research based service. Before tailoring the service, Ethane Web ... by other companies. The company has done its best ... impeccable and able to deliver outstanding results to clients. ...
(Date:8/29/2014)... effect, stimulating neurite extension in the presence ... enhancing nerve regeneration following nerve crush injury ... to stimulate nerve regeneration is limited because ... hypertension, and its considerable cost. With long-term ... drugs reportedly cause life-threatening infections. Like FK506, ...
(Date:8/29/2014)... The Fresh Diet, America’s premier gourmet meal delivery ... meal plan. Originating from The Fresh Diet’s commitment to ... designed to satisfy customers seeking a convenient, worry-free option ... to the growing demand by customers for non-meat menu ... with 14% of Americans identifying vegetarian meals as ‘more ...
(Date:8/29/2014)... 2014 Glendale Botox experts at ... Botox throughout the month of September. This special offer features ... syringes of Juvederm. Patients can take advantage of this special ... Glendale Botox experts will work with patients to determine if ... What is Botox? , Botox is a treatment made ...
Breaking Medicine News(10 mins):Health News:LeaseQ Announces That Recent Industrial Production Report Spells Good Things For The Equipment Leasing Industry 2Health News:LeaseQ Announces That Recent Industrial Production Report Spells Good Things For The Equipment Leasing Industry 3Health News:Ethane Web Technologies Launches a New Web Design Service 2Health News:The Fresh Diet America's #1 At-Home Meal Delivery Company, Debuts Fresh Vegetarian Meal Plan Offering All-Natural Ingredients 2Health News:The Fresh Diet America's #1 At-Home Meal Delivery Company, Debuts Fresh Vegetarian Meal Plan Offering All-Natural Ingredients 3Health News:Glenoaks Laser Center is Now Offering a Special Promotion on Botox for the Month of September 2
... New personalized service educates clients about Medicare; identifies best options ... , ... Belleville, Ill. (Vocus) September 10, ... expanding the services it offers to individuals with disabilities with ...
... PARSIPPANY, N.J., Sept. 10 DSM Pharmaceutical ... Nice LLC as agency of,record for marketing ... covers services for this DSM business group ... DSM Biologics and DSM Pharmaceuticals, Inc., ...
... 10, 2008)In recent years, private equity investors have ... by investigative reports and anecdotal evidence that these ... companies have found themselves under increased federal scrutiny. ... such conclusions may be premature. Private equity purchases ...
... and C14-UBT are the most commonly used non-invasive tests of ... tests depend also on the prevalence of H. pylori ... the tests depend also on the prevalence of H. ... imply higher sensitivity and lower specificity. There are reports suggesting ...
... for people who support affordable health insurance options for American ... ... politicians dispense,their health care ideas at party conventions and local rallies, ... to do so is at,AffordableHealthInsurance.NET -- a new social network that ...
... Inc.,(Nasdaq: ENCO ), a full service multinational ... countries for many of the world,s,leading pharmaceutical and ... an amendment (the "Amendment") to its letter of ... the,Amendment, the Company will acquire all of the ...
Cached Medicine News:Health News:Allsup's New Medicare Advisor Program Helps People with Disabilities Make Sound Healthcare Coverage Decisions 2Health News:Allsup's New Medicare Advisor Program Helps People with Disabilities Make Sound Healthcare Coverage Decisions 3Health News:Allsup's New Medicare Advisor Program Helps People with Disabilities Make Sound Healthcare Coverage Decisions 4Health News:Allsup's New Medicare Advisor Program Helps People with Disabilities Make Sound Healthcare Coverage Decisions 5Health News:DSM Pharmaceutical Products Announces the Appointment of That's Nice LLC as Agency of Record for Marketing 2Health News:DSM Pharmaceutical Products Announces the Appointment of That's Nice LLC as Agency of Record for Marketing 3Health News:Private equity companies purchase nursing homes, but care does not suffer 2Health News:Private equity companies purchase nursing homes, but care does not suffer 3Health News:Social Network for Affordable Health Care Supporters Stimulates a New Level of Interactivity and Dialogue 2Health News:Prologue Acquisition Update and Termination of Linkcon Business Combination 2Health News:Prologue Acquisition Update and Termination of Linkcon Business Combination 3Health News:Prologue Acquisition Update and Termination of Linkcon Business Combination 4Health News:Prologue Acquisition Update and Termination of Linkcon Business Combination 5
3 mm diameter roller blade in line with handle. Curved shaft. Flat handle. 15 mm from curve to tip....
5 mm diameter blade. Angled 45 degrees. Hexagonal handle....
0.5 mm wide x 1.5 mm long. Angled 20 degrees. Octagonal handle....
8 mm downcutting Royce blade. Angled shaft. 60 mm from angle to tip....
Medicine Products: