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Interim Results Presented at EASL from PROVE 1 Clinical Trial of,Investigational Drug Telaprevir in Patients with Genotype 1,Hepatitis C

clinical investigations of small numbers of patients will not be reflected in clinical trials involving larger numbers of patients, that unexpected and adverse outcomes in other ongoing clinical and nonclinical studies will occur, that the FDA or other regulatory authorities will require additional and unanticipated studies or clinical trial outcomes before granting regulatory approval, and other risks listed under Risk Factors in Vertex's Form 10-K filed with the Securities and Exchange Commission on March 1, 2007. Vertex disclaims any obligation to update the information contained in this press release as new data become available.

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Vertex Pharmaceuticals Incorporated
Lynne H. Brum, 617-444-6614
VP, Strategic Communications
or
Michael Partridge, 617-444-6108
Director, Corporate Communications
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Patricia Farrell, 617-444-6533
Director, Public Relations
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Lora Pike, 617-444-6755
Manager, Investor Relations
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Zachry Barber, 617-444-6470
Senior Media Relations Specialist
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Tibotec Pharmaceuticals, Ltd.
Karen Manson, Mobile: +32 479 894 799
VP Communications and Public Affairs
Office: +32 15 461 019


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