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Innovive Pharmaceuticals to Present Interim Data from Phase I Study,of INNO-406 at the American Society of Clinical Oncology Annual,Meeting

NEW YORK--(BUSINESS WIRE)--May 30, 2007 - INNOVIVE Pharmaceuticals, Inc. (OTCBB: IVPH) today announced that interim data from a Phase I trial of INNO-406, an orally bioavailable dual Bcr-Abl and Lyn-kinase inhibitor for Gleevec(R)-resistant or treatment-intolerant chronic myelogenous leukemia, will be presented at the 43rd American Society of Clinical Oncology Annual Meeting. The meeting takes place June 1- 5, 2007 at McCormick Place in Chicago, Illinois.

Information related to the presentation is as follows: -0-

Presentation Title: "A phase I study of INNO-406, a dual inhibitor of

                    Abl and Lyn kinases, in adult patients with

                    Philadelphia chromosome positive (Ph+) chronic

                    myelogenous leukemia (CML) or acute lymphocytic

                    leukemia (ALL) relapsed, refractory, or intolerant

                    of imatinib"

Abstract Number:    7046

Session:            General Poster Session, Leukemia, Myelodysplasia

                    and Transplantation, Poster Board #L2

Location:           S Hall A2, McCormick Place

Session Date:       Saturday, June 2, 2007

Session Time:       8:00 a.m. - 12:00 p.m.

About INNO-406

INNO-406 (formerly known as NS-187) is a potent, oral, rationally designed, dual Bcr-Abl and Lyn-kinase inhibitor currently being investigated in a Phase I clinical study. According to a study published in the journal Blood (Dec. 1, 2005), INNO-406 is 25- to 55-times more potent than imatinib in vitro and is at least 10-times as effective as imatinib mesylate in suppressing the growth of Bcr-Abl bearing tumors. INNO-406 has demonstrated activity in 18 of 19 imatinib-resistant cell lines. In addition to its Bcr-Abl inhibitory properties, INNO-406 inhibits Lyn kinase. Upregulation of Lyn kinase activity is a well recognized cause of imatinib resistance. Lyn kinase activation has also been documented in a v ariety of solid tumors, including prostate cancer.

About INNOVIVE Pharmaceuticals

INNOVIVE Pharmaceuticals, Inc. acquires, develops and commercializes novel therapeutics addressing significant unmet medical needs in the fields of oncology and hematology. The company has four drug programs in clinical development: INNO-406, Tamibarotene, INNO-206, and INNO-305, for the treatment of chronic myelogenous leukemia, acute promyelocytic leukemia, small cell lung cancer, and acute myelogenous leukemia, respectively. For additional information visit

Gleevec(R) is a registered trademark of Novartis Pharmaceuticals Corporation.


INNOVIVE Pharmaceuticals, Inc.
Steve Kelly, President and CEO, 212-716-1820
Media & Investor Relations:
Porter Novelli Life Sciences
Rachel Lipsitz, 619-849-5378


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