Navigation Links
Indevus Announces Presentation of Pagoclone Data at 47th Annual New,Clinical Drug Evaluation Unit Meeting

or worsened." Pagoclone produced numerically superior improvement at week 2 (p=.20) and statistically significant improvement at week 4 (p=.007) and at week 8 (p=.02) as compared to placebo. At week 8, 55% of pagoclone treated patients were improved compared to 36% of placebo treated patients. Open label data showed considerable gains after three months of open label treatment. For patients receiving placebo during the double blind phase, 36% were rated as improved, but following 3 months of open label treatment, 80% were rated as improved. For patients receiving active pagoclone during the double blind phase, 55% had been rated as improved, and following 3 additional months of open label treatment, 90% were rated as improved. These results indicate that, while the beneficial effects of pagoclone were evident within the 8-week double-blind phase, the magnitude of benefit continued to grow for at least three months.

The LSAS, measured at week 4 and week 8, is a validated measure of social anxiety symptoms. Stuttering is often co-morbid with symptoms of social anxiety which can be a disabling consequence of stuttering. Although patients with primary anxiety disorders were excluded from participating in the trial, pagoclone produced a trend for significant improvement in social anxiety symptoms (total LSAS score) compared to placebo at week 4 (p=.09) and week 8 (p=.07). On a subscale comprised of the elements of the LSAS that evaluate anxiety-provoking speaking situations, pagoclone produced statistically significant improvement at both week 4 (p=.02) and week 8 (p=.02). Approximately half the patients who participated in the double-blind phase had a high level of social anxiety symptoms pre-treatment, as measured using the LSAS. Patients treated with pagoclone demonstrated statistically significant improvements in the LSAS Total scale compared with placebo. During the open label extension, both groups, those receiving active pagoclone as well as those receiving
'"/>




Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Indevus Reports Positive Data From Phase III NEBIDO Trial
2. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
3. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
5. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
6. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
7. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
8. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
9. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
10. Protox Announces Positive Clinical Data from Prostate Cancer Study
11. Inspire Announces Webcast of Presentation at C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
Post Your Comments:
(Date:5/22/2015)... LONDON , May 22, 2015 ... early phase clinical research unit with a worldwide ... respected for its frequent publications in peer reviewed ... and European stakeholders and regulators in discussions about ... results.      (Logo: http://photos.prnewswire.com/prnh/20150522/745125) , ...
(Date:5/22/2015)... -- China Nepstar Chain Drugstore Ltd. (NYSE: NPD ) ("Nepstar" ... China based on the number ... Mr. Fuxiang Zhang as the Company,s Chief ... Rebecca Yingnan Zhang has been appointed as Chief ... immediately. Meanwhile, Ms. Zhang resigned from the position as ...
(Date:5/21/2015)... , May 21, 2015  When ... along the side of his neck, he ... took a couple weeks off from weight ... go away.                               A ... 26, was referred to Michel Kliot, ...
Breaking Medicine Technology:China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 2China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 3Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 2Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 3Northwestern Medicine Surgeons Develop New Approach to Removing Nerve Tumors 4
... 2012  PDL BioPharma, Inc. (PDL) (NASDAQ: PDLI ... fourth quarter and full year financial results for the ... 2012 after market close. PDL,s management will host a ... Eastern Time to discuss the financial results. ...
... 2012  ViroPharma Incorporated (NASDAQ: VPHM ) today ... orphan drug Plenadren ® (hydrocortisone, modified release tablet) ... Metabolism (JCEM), a leading scientific journal for endocrinology. Plenadren ... adrenal insufficiency in adults. The authors described ...
Cached Medicine Technology:PDL BioPharma to Announce Fourth Quarter and Full Year 2011 Financial Results on February 23, 2012 2Pivotal Data Demonstrating Efficacy of Plenadren® (Hydrocortisone, Modified Release Tablet) in Adrenal Insufficiency Published in the Journal of Clinical Endocrinology and Metabolism 2Pivotal Data Demonstrating Efficacy of Plenadren® (Hydrocortisone, Modified Release Tablet) in Adrenal Insufficiency Published in the Journal of Clinical Endocrinology and Metabolism 3Pivotal Data Demonstrating Efficacy of Plenadren® (Hydrocortisone, Modified Release Tablet) in Adrenal Insufficiency Published in the Journal of Clinical Endocrinology and Metabolism 4Pivotal Data Demonstrating Efficacy of Plenadren® (Hydrocortisone, Modified Release Tablet) in Adrenal Insufficiency Published in the Journal of Clinical Endocrinology and Metabolism 5Pivotal Data Demonstrating Efficacy of Plenadren® (Hydrocortisone, Modified Release Tablet) in Adrenal Insufficiency Published in the Journal of Clinical Endocrinology and Metabolism 6
(Date:5/25/2015)... A recent report for Mass Live ... as a direct result of an opiate overdose in the ... in overdose deaths attributed to prescription opiate medications, and heroin. ... about geography. This issue doesn’t care about race. This issue ... As the state of Mass. reels from the effects of ...
(Date:5/25/2015)... NV (PRWEB) May 25, 2015 After ... year, the radical science-based human wellness company Trivedi ... workshop event from their world-class series titled, “Consciousness is ... held on June 13, 2015 at the routinely allotted ... EST. The event will be made available to the ...
(Date:5/24/2015)... The Rolling Stones Zip Code summer stadium ... Petco Park. This iconic group is ready for their ... had a warmup show in Los Angeles at the Henry ... this beloved band not only played their Sticky Fingers album ... "Jumping Jack Flash," "Moonlight Mile" and "All Down the ...
(Date:5/24/2015)... (PRWEB) May 24, 2015 EnviroLeather™ ... launches “InkGard™ Plus” – a classic, rugged leather ... polymer allowing difficult stains, including ink, to be ... different colors suitable for corporate, healthcare, hospitality and ... line with EnviroLeather’s goal of developing products that ...
(Date:5/24/2015)... Lake Geneva, WI (PRWEB) May 24, ... Bea Mercy Health System CEO ... their principal and honored at the ... event held April 15 at Geneva ... include (by school): ,     -Badger High ...
Breaking Medicine News(10 mins):Health News:Opioid Deaths Increase by 33 Percent Since 2012 in Mass. 2Health News:Hundreds of People Are Thrilled to Hear that Trivedi Master Wellness™ Promises to Hold Another Workshop in June 2015 2Health News:Hundreds of People Are Thrilled to Hear that Trivedi Master Wellness™ Promises to Hold Another Workshop in June 2015 3Health News:The Rolling Stones Tickets in San Diego, Orlando, Minneapolis, Dallas, Pittsburgh, Indianapolis, Atlanta, Detroit, Milwaukee, Kansas City, Columbus, Nashville & Raleigh 2Health News:EnviroLeather By LDI Launches "InkGard Plus" - Stain Resistant Faux Leather 2Health News:Mercy Foundation Honors 16 Students for Making a Difference - Mercy Health System Javon Bea 2
... Hall of Fame inductees Jackson Browne and Graham Nash ... biggest problem: the health of our peopleWASHINGTON, Jan. 6 ... The Vineeta Foundation, a health and human rights organization, ... the Health for All Blue Diamond Ball will be ...
... FASgen, Inc. is pleased to announce that it has ... Inc. This agreement will give Centocor, Inc. and ... the opportunity to discover and develop novel small molecule ... selective inhibition of Fatty Acid Synthase (FAS) for ...
... 6 Nanotechnology can be described as,the ... changing the way many,industries think of surface ... boat hull, a self-cleaning aircraft or a ... commercial reality using nanotechnology,materials and concepts. Nanovere ...
... Heine and Riester, giving physicians and researchers a one-stop online shop ... ... (Vocus) January 6, 2009 -- ORSupply.com, the largest online marketplace for ... unveiling a new range of otoscopes from Welch Allyn, Heine, and ...
... of member self-scheduling via the Internet , ... ... the industry leader in online customer self-scheduling software, announced several ... base. Major program providers such as Lifecare, Inc., which ...
... Jan. 6 Dr. Siegal,s Direct Nutritionals, ... ) and,worldwide distributor of the internationally-popular Dr. ... products, today announced,that renowned physician, author, and ... attend a grand opening event at the ...
Cached Medicine News:Health News:Health for All Blue Diamond Ball Scheduled to Celebrate Obama's Inauguration 2Health News:FASgen, Inc. Announces Research and License Agreement With Centocor, Inc. 2Health News:Nanotechnology Causes Disruption - Cross Industry 2Health News:ORSupply.com Unveils Largest Selection of Otoscopes Available Anywhere 2Health News:ORSupply.com Unveils Largest Selection of Otoscopes Available Anywhere 3Health News:Online Scheduling Software Is Revolutionizing the Wellness Industry 2Health News:Dr. Sanford Siegal and Weight Loss Success Story Josie Raper, Who Appears on Current People Magazine Cover, to Attend Grand Opening of Dr. Siegal's COOKIE DIET Store in Beverly Hills 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: