Navigation Links
In New Study, Duloxetine Was Equally Effective, Regardless of,Switch Method, in Reducing Painful Symptoms in Ssri Non- or,Partial-responders with Depression

ng of the study. The dosage could be increased to a maximum of 120 mg/day based on the investigator’s discretion.1

The primary data disclosure took place at a major medical conference in December 2006.5 The primary objective of the overall study was to demonstrate the non-inferiority of Direct Switch (DS) compared with Start-taper Switch (STS) based on changes in HAMD17 total scores. Overall, that initial data disclosure showed that switch to duloxetine was associated with significant improvements in the emotional symptoms of depression, and was well tolerated and safe, regardless of which SSRI the patient was taking at study entry.

This new analysis focused on the prevalence and severity of painful symptoms following the switch to duloxetine and in relation to switch method. The study participants, as a group, had average pain scores indicating clinically significant physical pain. Ten weeks after switching to duloxetine, patients made significant improvements on all pain measures evaluated, regardless of which switch method was used.1

Efficacy, safety, and tolerability outcomes following Direct Switch (DS) from SSRI to duloxetine were similar to those observed for Start-taper Switch (STS). The most commonly reported adverse events in the study were headache (13.1 percent for DS vs. 9.7 percent STS), dry mouth (10.4 percent DS vs. 11.9 percent STS), and nausea (8.2 percent DS vs. 8.1 percent STS). No adverse event was reported by significantly more patients in one group compared with the other. An excess of adverse events was not evident following switch from any particular SSRI.1

“This study provides some much-needed clinical evidence to help physicians successfully switch patients from one antidepressant to another when they remain depressed,” Montejo said. “It also highlights the continued prevalence and severity of painful symptoms among patie
'"/>




Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. In New Study, Duloxetine Reduced Non-specific Pain and Emotional Symptoms Associated with Depression
2. Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression
3. Roxro Pharma’s Novel Intranasal Pain Reliever Effective, Well Tolerated in Phase 3 Study
4. MabThera Significantly Increases Survival of Lymphoma Patients Regardless of Chemotherapy Regimen
5. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
6. Cimzia Effective in Reducing Signs and Symptoms of Rheumatoid Arthritis
7. The Lancet Publishes PREVAIL Study Results Showing Lovenox Superiority Over Unfractionated Heparin for Reducing the Risk of Venous ThromboEmbolism in Patients With Acute Ischemic Stroke
8. The International Myeloma Foundation Says New Clinical Trial Results Could Improve Survival While Reducing Side Effects For Many Patients
9. New Study Confirms Role for Pertussis Immunization of Entire Family in Reducing Infant Pertussis
10. Dharma Therapeutics Shows IDDS Is Effective in Reducing Pain Associated With Insertion of an Intravenous Catheter in Their Phase 2 Clinical Trial
11. Pooled Studies Showed Desvenlafaxine Succinate Significantly Improved Painful Symptoms and Anxious Symptoms Associated with Major Depressive Disorder in Adults, Compared With Placebo
Post Your Comments:
(Date:8/28/2015)... , Aug. 28, 2015  With the heroin ... reaching deadlier heights, Jacksonville -based Lakeview ... Hemphill is helping to explain why fentanyl is ... approximately 40 to 50 times more potent than pharmaceutical ... users as heroin, the risk of death skyrockets. ...
(Date:8/28/2015)... August 28, 2015 According to ... Tumor (Breast, Lung, Prostate) Type (Protein & Genetic Biomarkers) ... Discovery, Prognostic) & Geography - Global Forecast to 2020", ... to reach around 17,689.0 Million USD by 2020 at ... 2015 to 2020. Browse 191 Tables ...
(Date:8/28/2015)... Research and Markets ... the "12th Annual Report and Survey of ... their offering. The 2015 12th Annual ... Production is the most recent study of biotherapeutic ... future capacity and production. The report contains the ...
Breaking Medicine Technology:Lakeview Health's Dr. Philip Hemphill Explains Why Heroin Addicts Are Now Dying of Fentanyl Overdoses 2Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 2Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 3Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 4Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 512th Annual Report and Survey of Biopharmaceutical Manufacturing Capacity and Production 2
... NEW YORK, Jan. 28, 2011 Get content ... http://www.thenewsmarket.com/Releases/StoryDetailPage.aspx?GUID=edb04e54-24b1-41bc-b1f7-aac03a4e0b31&lr=ls British Prime Minister David ... double its current contribution to polio eradication. Mr. ... Global Polio Eradication Initiative as he announced the ...
... 28, 2011 Drug safety remains front and center ... agency strives to improve the public,s perception of the ... its reputation among consumers and recognizes that its diligence ... role in that effort. One issue that ...
Cached Medicine Technology:Navigating the Gray Areas of Post-Marketing Surveillance 2
(Date:8/28/2015)... ... August 28, 2015 , ... Approximately 2,000 ... Zoo to celebrate children helping children, a thank you to the many creative ... have contributed to the United Methodist initiative to end malaria deaths. , The ...
(Date:8/28/2015)... ... 28, 2015 , ... An article published August 19th by the ... gone through to open a pizzeria in Westchester. Mr. LaRocco was aware from opening ... months, but the current process, having already gone on for over a year, is ...
(Date:8/28/2015)... TX (PRWEB) , ... August 28, 2015 , ... For ... Center is taking part with their subsidiary USPI Tenet Health. , The American Heart ... fight heart disease and stroke. They believe that together, a difference can be made. ...
(Date:8/28/2015)... Baltimore, MD (PRWEB) , ... August 28, 2015 , ... ... reduction system from Merz, received FDA clearance for results that last for two ... clearance is exciting news for patients who are looking for a long-lasting, effective solution ...
(Date:8/28/2015)... ... August 28, 2015 , ... On May 30th, 2015, Best Drug Rehabilitation, a ... “Music With A Mission” benefit concert in Mendon, IL. Held in the Show Barn ... to support music education programs in the underfunded local school districts of Mendon at ...
Breaking Medicine News(10 mins):Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:Article on Building Approval Process for LA Business Highlights the Need for a Bridge Between Businesses and City Officials, says Fire Protection Group Inc. 2Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 3Health News:New Video Released on "Music With A Mission" Benefit Concert Headlining Artist Cadillac Three & Best Drug Rehabilitation 2
... By Denise Mann HealthDay Reporter , WEDNESDAY, Dec. ... help us say "bon voyage" to the dreaded "cruise-ship" tummy ... off the norovirus that has sickened many cruisers in recent ... cramping, diarrhea and vomiting, and spreads easily from person to ...
... 2011 A dramatic increase in the incidence of ... bowel syndrome, has led to concern about how modern ... the context of a foresight study under the auspices ... scientists has examined the challenges associated with chronic inflammatory ...
... time, scientists have altered natural bioelectrical communication among cells ... be created at a particular location within a vertebrate ... (frog) embryos, biologists at Tufts University,s School of Arts ... eyes outside of the head area. The researchers ...
... Reporter , WEDNESDAY, Dec. 7 (HealthDay News) -- Women ... avoiding unnecessary medical radiation, forgoing menopausal hormone therapy and ... about using hair dyes or cellphones, a broad new ... on environmental factors that may affect breast cancer risk, ...
... The latest episode in the American Chemical Society,s ... discusses the discovery of bisphenol A (BPA) in 94 ... recycling of those receipts spreads BPA to paper napkins, ... the podcast, Kurunthachalam Kannan, Ph.D., explains that manufacturers produce ...
... too multifaceted to be left solely in the hands of ... latest Healthy People 2020 Objectives for the Nation. A ... a program that sets the national agenda for health promotion ... goals. Two papers published in the December ...
Cached Medicine News:Health News:Vaccine Might One Day Prevent 'Cruise Ship' Stomach Bug 2Health News:Vaccine Might One Day Prevent 'Cruise Ship' Stomach Bug 3Health News:Scientists identify strategies to conquer lifestyle and genetic factors related to chronic diseases 2Health News:Scientists identify strategies to conquer lifestyle and genetic factors related to chronic diseases 3Health News:Scientists identify strategies to conquer lifestyle and genetic factors related to chronic diseases 4Health News:Researchers discover that changes in bioelectric signals cause tadpoles to grow eyes in back, tail 2Health News:Researchers discover that changes in bioelectric signals cause tadpoles to grow eyes in back, tail 3Health News:Expert Panel Pinpoints Environmental Culprits in Breast Cancer 2Health News:Expert Panel Pinpoints Environmental Culprits in Breast Cancer 3Health News:Expert Panel Pinpoints Environmental Culprits in Breast Cancer 4Health News:Recycled thermal cash register receipts spread BPA to other paper products: ACS podcast 2Health News:Improving health will take a village 2
Rees bayonet forceps, standard, 5-1/2", TC....
... Channel Implants, designed to accept ... surgeon with an excellent reconstructive ... and floor blowout defects. Each ... placement of one or more ...
... is designed to augment areas ... midface, including the inferior orbital ... in the hollow under the ... implant aids in restoring the ...
The new Inferior Medial Orbital Rim Implant (IMORI) provides surgeons with an excellent alternative for patients with a deficient or recessed "tear trough" area often characterized as a look of fatig...
Medicine Products: