Navigation Links
In New Study, Duloxetine Reduced Non-specific Pain and Emotional,Symptoms Associated with Depression

MADRID, Spain, 19 march 2007 - The antidepressant duloxetine, at a once-daily dose of 60 mg, significantly reduced non-specific pain and emotional symptoms associated with depression in a new, eight-week, placebo-controlled study of 327 adult patients with at least moderate pain and major depression. The results were presented today at the 15th European Congress of Psychiatry (AEP) in Madrid, Spain.

Duloxetine, a member of a class of drugs commonly referred to as serotonin and norepinephrine reuptake inhibitors (SNRIs), is approved in more than 70 countries for the treatment of major depression.

“Whereas traditionally, the focus has been on treating only emotional symptoms of depression, we now know that the presence of physical symptoms, specifically pain, can obscure the diagnosis and complicate the management of patients,” said Professor Koen Demyttenaere, Department of Psychiatry at University Hospital Gasthuisberg in Belgium and lead study investigator. “In this study of depressed patients with at least moderate pain, duloxetine helped by significantly reducing both painful and emotional symptoms of depression, and in decreasing the interference of pain with functioning.”

In the study:
Average pain scores, the primary outcome measured, decreased significantly among patients treated with duloxetine by 45 percent (on an 11-point Likert scale from 5.7 at baseline to 3.13 at the final visit in Week 8) compared with a decrease of 29 percent (from 5.7 to 4.06) among those taking placebo (p< 0.001).
Duloxetine significantly reduced core emotional symptoms, as assessed by the Montgomery-Asberg Depression Rating Scale (MADRS), by 56 percent (from an average score of 29.6 at baseline to 12.91 at Week 8), compared with a 39-percent reduction (from 29.6 to 18.29) in patients taking placebo (p<0.0001).
53 percent of duloxetine-treated patients reached remis
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression
2. Newly Published Data Demonstrates Superiority of Cipralex Over Duloxetine for Acute Treatment of Depression
3. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
4. Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone
5. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
6. Lipitor Reduced the Risk of Coronary Events by Half and Stroke by Nearly One-Third in High-Risk Patients with Type 2 Diabetes Who Experienced a Recent Stroke
7. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
8. Arterial Plaque Significantly Reduced in Women Age 50-59 Taking Hormones, Says New Analysis of Womens Health Initiative Data
9. New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy
10. Pivotal Phase III Trial Showed Promacta (eltrombopag olamine) Raised Platelet Counts and Reduced Bleeding in Patients With Chronic ITP
11. Preclinical Study Finds Protease Inhibitor-Resistant HIV May Have Reduced Potential to Develop Resistance to Panacos Bevirimat
Post Your Comments:
(Date:5/22/2015)... KING OF PRUSSIA, Pa. , May 22, 2015 ... CSL Behring its 2015 Corporate Leadership Award as ... science and improving the care of the bleeding disorders community.  ... and Managing Director, CSL Limited, during the NHF Annual Spring ... May 21. "The National Hemophilia Foundation is dedicated ...
(Date:5/22/2015)... InspireMD, Inc. (NYSE MKT: NSPR) ("InspireMD" or the "Company"), ... that its CGuard TM Embolic Prevention System reported positive ... Musialek , at the EuroPCR conference on May ... PARADIGM, an investigator-initiated P rospective evaluation of ... revascularization I n symptomatic and increased-risk asymptomatic carotid artery ...
(Date:5/22/2015)... 2015 AcelRx Pharmaceuticals, Inc. (Nasdaq: ACRX ... and commercialization of innovative therapies for the treatment of ... executive officer Howie Rosen will be presenting ... Tim Morris will be presenting at JMP ... are as follows: Jefferies 2015 Healthcare Conference ...
Breaking Medicine Technology:National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 2National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 3National Hemophilia Foundation Honors CSL Behring with Corporate Leadership Award 4InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 2InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 3InspireMD's CGuardTM Highlighted at Clinical Presentation at EuroPCR 2015 Conference 4AcelRx Pharmaceuticals to Present at Two Upcoming Investor Conferences In June 2
... Burrill & Company, a San Francisco-based global leader ... Equity, Merchant Banking and Media, is pleased to announce ... "For life sciences companies, accessing capital has ... CEO, Burrill & Company. "The creation of an Alternative ...
... Business Solutions is pleased to announce that ... eClinical suite, has agreed to serve as advisors ... REGISTRAT-MAPI has utilized Acceliant since 2007, for many of ... and knowledge of the industry accumulated conducting Late Phase ...
Cached Medicine Technology:Burrill Merchant Banking Establishes Alternative Equities Group 2Burrill Merchant Banking Establishes Alternative Equities Group 3REGISTRAT-MAPI & Trianz Collaborate on Developing Acceliant EDC Platform’s ePRO Capabilities 2REGISTRAT-MAPI & Trianz Collaborate on Developing Acceliant EDC Platform’s ePRO Capabilities 3
(Date:5/23/2015)... May 23, 2015 Injury lawyer Steven H. ... been passed by the Maryland legislature but which has not ... General Assembly passed HB 449 with overwhelming bipartisan ... not signed it into law. This bill ensures that fracking ... growing that demonstrates the danger of fracking to our water ...
(Date:5/22/2015)... 2015 Mountain Point Medical Center, a campus ... ceremony on Friday, May 29, 2015 at 11 a.m., followed ... The new medical center, set to officially open on June ... UT 84043. , “The opening of Mountain Point Medical ... Utah County community,” said Kent Loosle, CEO of Mountain Point ...
(Date:5/22/2015)... 22, 2015 Omar Ahmad Barrada, a ... participate in the 2015 Congress of Future Medical Leaders ... a gathering of “America’s highest achieving high school students.” ... healthcare, set new goals and learn better study habits,” ... surgery, during which we can ask the surgeons questions.” ...
(Date:5/22/2015)... 2015 Family, friends, students, colleagues, mentors ... oncologist, Dr. LaSalle D. Leffall, on Monday, May 18, ... after Grand Rounds in the hospital’s Tower Auditorium. Leffall’s ... the auditorium, trying to keep the secret. “I’d like ... sees me, he’ll know something is up,” she said. ...
(Date:5/22/2015)... (PRWEB) May 22, 2015 According to a ... all generations are equally as likely to worry about what ... 75% Gen X, 77% Boomers, 69% Silent Generation), which may ... they are scared of aging, particularly Millennials (47%), Gen X’ers ... Harris Poll in April, 2015 among more than 2,000 U.S. ...
Breaking Medicine News(10 mins):Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 2Health News:Baltimore Attorney Urges Governor Hogan to Sign the Fracking Moratorium Bill 3Health News:Mountain Point Medical Center, a Campus of Jordan Valley Medical Center, Hosts Ribbon Cutting Ceremony and Community Celebration on Friday, May 29, 2015 2Health News:Milton Hershey School Student Chosen for Congress of Future Medical Leaders 2Health News:Colleagues Surprise Dr. LaSalle Leffall with 85th Birthday Celebration 2Health News:New Study Reveals America’s Fear of Aging 2Health News:New Study Reveals America’s Fear of Aging 3
... Versus,Technology, Inc. ("Versus" or the "Company") announced revenues of,$1,176,000 ... a decrease of,8% compared to revenues of $1,283,000 for ... nine months ended July 31, 2008, were $4,026,000,compared to ... a 13%,increase. Versus, quarterly revenues can vary significantly depending ...
... from brain injury, not injury itself, associated with increased plaque ... researchers has described hourly changes in a protein in the ... Alzheimer,s disease. , In a 2005 study, the protein, ... communication in a mouse model of Alzheimer,s disease. When brain ...
... Paul M. Parker has been performing lipoabdominoplasty, an advanced type of ... their sculpted tummies and their quick recovery from surgery. In the ... the procedure making the results and recovery even better. , ... ...
... Online Users to Learn about Each Candidate,s Health Care Platform ... ... Miami, FL (PRWEB) August 28, 2008 -- HealthCare.com, Inc. ... announced today the launch of "HealthDecision ,08: Obama and McCain ...
... of Dimes Volunteer to take part in Signature,Chefs Auction ... Hell,s,Kitchen to a kitchen near you: Chef Rahman "Rock" ... Dimes Signature Chef Auctions open to the public,nationwide this ... first national celebrity chef,spokesperson. In this role, Chef Rock, ...
... Aug. 27 Replidyne, Inc.,(Nasdaq: RDYN ) ... current employee headcount by approximately 80% to 5 ... during September 2008 and October,2008. As a result ... of REP3123, its investigational agent for the,treatment of ...
Cached Medicine News:Health News:Versus Technology Announces Third Quarter Results 2Health News:Versus Technology Announces Third Quarter Results 3Health News:Versus Technology Announces Third Quarter Results 4Health News:Versus Technology Announces Third Quarter Results 5Health News:Versus Technology Announces Third Quarter Results 6Health News:Scientists Track Hourly Changes in Alzheimer's Protein 2Health News:Lipoabdominoplasty: A New Type of Tummy Tuck Gets Even Better 2Health News:Lipoabdominoplasty: A New Type of Tummy Tuck Gets Even Better 3Health News:Lipoabdominoplasty: A New Type of Tummy Tuck Gets Even Better 4Health News:HealthCare.com Launches HealthDecision '08: Obama and McCain on Health Care 2Health News:HealthCare.com Launches HealthDecision '08: Obama and McCain on Health Care 3Health News:Chef Rock to Rock Signature Chefs Auctions(R) Nationwide 2Health News:Replidyne Announces Restructuring of Operations 2
Inquire...
Inquire...
For use with Snap-In Snap-Out-II tip inserts. Available in five styles, the Snap-In Snap-Out-II Laparoscopic Instrument Handles offer the broadest range available....
Inquire...
Medicine Products: