In 2004, Abbott introduced the systems third generation, AxSYM Plus 5.0, which includes improved ergonomics, increased ease-of-use and hardware and software upgrades that provide high-integrity results with less operator intervention. The system is designed to handle 80 to 120 tests per hour, making it suitable for all but the highest-volume environments. In December 2005, Abbott announced their submission to the FDA seeking pre-market approval (PMA) for a hepatitis HBsAg/Confirmatory test for use on its AxSYM instrument. In the second half of 2006, Abbott plans to introduce the ARCHITECT ci16200, a high-volume integrated system.
In 2004, Tosoh Bioscience, Inc., headquartered in Tokyo, Japan, introduced their fully integrated floor standing immunoassay analyzer, the AIA-1800. With this product, Tosoh combines an appreciable throughput (180 tests per hour) with a thorough test menu, automated functions and ease-of-use in a mid-sized format. The test menu reagents for the AIA-1800 are made in the AIA-PACK test cup format, described as pre-measured units of dried reagent that require no preparation or on-board refrigeration. The test menu for the AIA-1800 includes tumor markers, thyroid, reproductive, cardiac, and anemia, and metabolic assays.
Automated features of the AIA-1800 include bar-coded primary tube sampling, auto dilution, auto pretreatment, dual clot detection and automatic inventory management of reagents and supplies. To make operation user friendly, Tosoh uses a Windows-based interface to drive the continuous workflow features. The thorough UK Medicines and Healthcare products Regulatory Agency (MHRA) report notes good reliability and customer support of the AIA-1800.