CAMBRIDGE, Mass.--(BUSINESS WIRE)--May 24, 2007 - ImmunoGen, Inc.
(Nasdaq: IMGN), a biopharmaceutical company that develops targeted
anticancer therapeutics using its Tumor-Activated Prodrug (TAP)
technology, today announced that clinical findings for three
different TAP compounds for the treatment of solid tumors are to be
reported at the 43rd American Society of Clinical Oncology (ASCO)
Annual Meeting to take place June 1-5, 2007 in Chicago, IL.
Trastuzumab-DM1 (abstract #1042)
"A phase I study of trastuzumab-MCC-DM1 (T-DM1), a
first-in-class HER2 antibody-drug conjugate (ADC), in patients
(pts) with HER2+ metastatic breast cancer (BC)."
-- Saturday, June 2, 2:00-6:00 pm: Breast Cancer - Metastatic
General Poster Session (poster #G4).
-- Trastuzumab-DM1 is in development by Genentech.
HuC242-DM4 (abstract #3062)
"A phase I study of a CanAg-targeted immunoconjugate,
huC242-DM4, in patients with Can Ag-expressing solid tumors."
-- Sunday, June 3, 8:00 am-12:00 noon: Developmental
Therapeutics: Immunotherapy General Poster Session (poster
#F14).
-- HuC242-DM4 is wholly owned by ImmunoGen.
HuN901-DM1 (abstract #18084)
"Phase II trial of huN901-DM1 in patients with relapsed small
cell lung cancer (SCLC) and CD56-positive small cell
carcinoma."
-- To be published as abstract in the Journal of Clinical
Oncology.
-- HuN901-DM1 is wholly owned by ImmunoGen.
About ImmunoGen's TAP Technology
ImmunoGen created its TAP technology to enhance the anticancer
activity of tumor-targeting antibodies while maintaining a
favorable tolerability profile. The Company attaches to an antibody
one of ImmunoGen's proprietary cell-killing agents. The antibody
serves to deliver the agent specifically to cancer cells and the
agent serves to kill the cancer cells. The agent is attached using
one of the Company's "linkers." ImmunoGen has developed alte
'"/>
Page: 1 2 3 Related medicine technology :1.
Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial2.
Neose Announces Presentation of Positive Preclinical Data on
GlycoPEGylated Factor VIIa at the XXI Congress of the International
Society on Thrombosis and Haemostasis3.
Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy
of BF-200 ALA In Actinic Keratosis4.
YM BioSciences Announces Secondary Efficacy and Safety Findings in
Randomized Phase IIB Aerolef Trial5.
BioSante Pharmaceuticals Announces New Findings for Potential Bird
Flu Vaccine6.
Portola Pharmaceuticals Announces Positive Data from a Phase II
Study of its Factor Xa Inhibitor at the XXI Congress of the
International Society on Thrombosis and Haemostasis7.
Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for
Oral Oleoyl-estrone8.
AVI BioPharma Partner Cook Medical Announces Completion of Patient
Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of
Cardiovascular Disease9.
Protox Announces Positive Clinical Data from Prostate Cancer Study10.
Inspire Announces Webcast of Presentation at C.E. Unterberg, Towbin
Emerging Growth Opportunities Conference11.
NexMed Announces Completion of Patient Enrollment in Two Pivotal
Phase 3 Studies for Anti-Fungal Product