Navigation Links
ImClone Systems Showcases Extensive Research and Development,Program at the AACR Annual Meeting

NEW YORK--(BUSINESS WIRE)--Apr 19, 2007 - IgG1 monoclonal antibodies developed by ImClone Systems Incorporated (NASDAQ: IMCL) were the focus of 44 total presentations at the recently concluded 98th Annual Meeting of the American Association for Cancer Research (AACR), including seven oral presentations and 37 posters.

Important ERBITUX(R) (cetuximab) clinical data were the focus of two back-to-back oral presentations leading off the "Breakthroughs in Clinical Research" Plenary Session on April 16, 2007, which highlights the most important clinical studies presented at this prestigious meeting. The remaining presentations showcased ImClone's extensive research and development program with results from studies involving both ERBITUX, an IgG1 monoclonal antibody that targets the epidermal growth factor receptor (EGFR), and multiple investigational monoclonal antibodies in the ImClone pipeline that target other critical cancer pathways.

Like ERBITUX, the monoclonal antibodies in the ImClone pipeline are all type 1 immunoglobulin G (IgG1) antibodies. In vitro, IgG1 antibodies elicit antibody-dependent cellular cytotoxicity (ADCC), which can kill cancer cells and may contribute to their overall therapeutic effects. These novel fully human antibodies, many of which are in early phase clinical testing, target cell surface receptors in various signaling pathways known or believed to play important roles in the growth and proliferation of tumors or tumor vasculature. Specific targets include insulin-like growth factor-1 receptor (IGF-1R), vascular endothelial growth factor receptor-1 (VEGFR-1), VEGFR-2, VEGFR-3, platelet-derived growth factor receptor alpha (PDGFR(alpha)), FMS-like tyrosine kinase 3 receptor (FLT3), fibroblast growth factor receptor 3 (FGFR3), among others.

"Our pipeline consists of a robust collection of IgG1 monoclonal antibodies targeted against cellular pathways that are emerging as cri
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Phase I Results for ImClone Pipeline Anti-IGF-1R Monoclonal Antibody IMC-A12 Presented at ASCO
2. When Volume Matters, Immunoassay Systems Deliver
3. Genetic Analysis Systems Enter the Clinical Mainstream
4. New Quality Control Systems for Every Laboratory Application
5. Immunoassay Systems - Your Laboratory Workhorse
6. SPIRIT Clinical Data Reaffirm Strength of Taxus and Promus Drug-Eluting Coronary Stent Systems
7. Extensive Clinical Data on Erbitux Presented at the 2007 ASCO Annual Meeting
8. NIEHS Researchers Identify Enzyme Critical in DNA Replication
9. Stanford Researchers Find Brain Pathway of Depression in Rats
10. Suven Life Sciences Presenting Pre-clinical data of their NCE’s SUVN-502 and SUVN-507at International Brain Research Organization (IBRO) 2007 World Congress of Neuroscience
11. From Clinical Cancer Research: Rethinking Therapeutic Cancer Vaccine Trials
Post Your Comments:
(Date:7/7/2015)... , July 7, 2015 Noting the need ... pricing policies currently practiced by the rapidly consolidating pharmacy ... (SCPC) today praised Ohio Governor ... a new state effort to help pull back the ... "We applaud Governor Kasich for bringing badly-needed ...
(Date:7/7/2015)... , July 7, 2015 Biobanks ... Helping Your Influence  ,Are you interested ... so, now gain technological and commercial predictions from 2015. ... explore trends in research and development, results, opportunities and ... visiongain shows you what,s possible for biobanking and ...
(Date:7/7/2015)... , 7. Juli 2015 ... -Technik für klinische Studien, gab heute bekannt, dass ... führendes Unternehmen bei Gewinnung und Erhalt von Patienten ... Tochtergesellschaften MediciGlobal , Ltd. und Access to ... auch einen Dienst zum Auffinden von Patienten, die ...
Breaking Medicine Technology:National LTC Pharmacy Leader Praises Kasich Effort to Bring Transparency to PBM Drug Pricing 2National LTC Pharmacy Leader Praises Kasich Effort to Bring Transparency to PBM Drug Pricing 3Biobanking for Medicine: Technology, Industry and Market 2015-2025 2Biobanking for Medicine: Technology, Industry and Market 2015-2025 3Biobanking for Medicine: Technology, Industry and Market 2015-2025 4Biobanking for Medicine: Technology, Industry and Market 2015-2025 5Biobanking for Medicine: Technology, Industry and Market 2015-2025 6Biobanking for Medicine: Technology, Industry and Market 2015-2025 7Biobanking for Medicine: Technology, Industry and Market 2015-2025 8Biobanking for Medicine: Technology, Industry and Market 2015-2025 9Biobanking for Medicine: Technology, Industry and Market 2015-2025 10BioClinica übernimmt MediciGroup 2BioClinica übernimmt MediciGroup 3BioClinica übernimmt MediciGroup 4
... Held at 9:00 a.m. Eastern Time Today, May 26, ... (Nasdaq: UTHR ) announced today that the ... ADCIRCA(TM) (tadalafil) tablets for oral administration, with a recommended ... type 5 (PDE5) inhibitor for the treatment of pulmonary ...
... 23 Amid all the speculation over what course ... Replikins Ltd. ( www.replikins.com ) last week ... and determined that the infectivity of the H1N1 virus ... low for the immediate future.The company,s quantitative analysis of ...
Cached Medicine Technology:FDA Approves ADCIRCA(TM) (Tadalafil) Tablets for the Treatment of Pulmonary Arterial Hypertension 2FDA Approves ADCIRCA(TM) (Tadalafil) Tablets for the Treatment of Pulmonary Arterial Hypertension 3FDA Approves ADCIRCA(TM) (Tadalafil) Tablets for the Treatment of Pulmonary Arterial Hypertension 4Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data 2
(Date:7/7/2015)... ... July 07, 2015 , ... ... Southwest, including Giant, Mustang, Sun Dial and Howdy’s, raised more than $524,286 ... 2015 fundraising goal by nearly $100,000, to help support children fighting muscular ...
(Date:7/7/2015)... ... July 07, 2015 , ... Difass USA, a modern supplement brand committed ... stressful days at work is knowing that there is hopefully a vacation to look ... free as imagined. Planning for a vacation can be quite stressful, and it’s difficult ...
(Date:7/7/2015)... ... July 07, 2015 , ... This week Northeast ... brand new website. The website’s goal is to provide patients with detailed information ... tools, including requesting appointments online. , Part of the center’s rebranding efforts, the ...
(Date:7/7/2015)... ... July 07, 2015 , ... ... Consulting announced today that the two firms have merged to form Camber ... health and biopharma sectors. The merger combines SwitchPoint’s strategy consulting expertise with ...
(Date:7/7/2015)... ... 2015 , ... Greatist today announced the acquisition of Blood, ... the most fun activities to do with friends. , The acquisition of BSC strengthens ... opportunity for events, e-commerce, and brand partnerships. , “I’ve been a huge fan of ...
Breaking Medicine News(10 mins):Health News:Western Refining Raises $524,286 to Help Send Kids with Neuromuscular Disease to MDA Summer Camp 2Health News:Western Refining Raises $524,286 to Help Send Kids with Neuromuscular Disease to MDA Summer Camp 3Health News:Difass USA Offers Eight Tips to Help Relax and Enjoy Summer Vacation 2Health News:Difass USA Offers Eight Tips to Help Relax and Enjoy Summer Vacation 3Health News:Northeast Nebraska Imaging Launches New Patient Friendly Website 2Health News:SwitchPoint and Hope Consulting Have Merged to Form Camber Collective 2Health News:Greatist Acquires Active Lifestyle Brand Blood, Sweat & Cheers 2
... 19 Studies have shown wearing a helmet while riding a ... yet every three days, a child in the United States is ... children are treated in emergency rooms due to bicycle-related head injuries. ... of Michigan C.S. Mott Children,s Hospital National Poll on Children,s ...
... in patients , FRIDAY, June 19 (HealthDay News) -- ... explain brain gray matter reductions experienced by patients with ... an association between fibromyalgia and reductions in gray matter, ... In this new study, Dr. Patrick B. Wood, of ...
... of E. coli infection in 28 states , ... warning consumers not to eat any Nestlé Toll House refrigerated ... coli contamination. , In response to the Food and ... voluntarily recalling its Toll House refrigerated cookie dough items. , ...
... 19 Warner Chilcott Limited (Nasdaq: WCRX ) ... Mid-Year Equity Conference on Wednesday, June 24, 2009 at 2:30 ... Fuhrmann, Senior Director, Investor Relations. , , Warner Chilcott,s ... www.wcrx.com under the Investor Relations tab. An ...
... , Brio Active opens its doors this month, offering a ... its core. , , DENVER, June 19 Brio ... vibration, a relatively new fitness concept in the U.S., with ... strength, flexibility, balance, energy, bone density, and neuromuscular coordination. ...
... ... ... - Last week, the World Health Organization declared the H1N1 virus, also commonly referred to ... urging healthcare providers to take precautions to limit the spread of the virus from infected ...
Cached Medicine News:Health News:Bicycle Helmet Laws For Kids Effective But Not Yet the Norm 2Health News:Bicycle Helmet Laws For Kids Effective But Not Yet the Norm 3Health News:Bicycle Helmet Laws For Kids Effective But Not Yet the Norm 4Health News:Nestlé Recalls Raw Cookie Dough Products 2Health News:Brio Active Brings Whole Body Vibration Fitness to Cherry Hills Village 2Health News:Real-Time Locating Technology Helps Contain Pandemic Outbreaks 2Health News:Real-Time Locating Technology Helps Contain Pandemic Outbreaks 3Health News:Real-Time Locating Technology Helps Contain Pandemic Outbreaks 4
IOL choppers for positioning intraocular lenses. Blunt tip avoids damage to intraocular lenses. For .20mm diameter holes and larger....
...
...
...
Medicine Products: