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ISTA Pharmaceuticals Announces Positive Preliminary Results from,Ecabet Sodium Phase IIb Study

ights held by third parties, and such risks and uncertainties as detailed from time to time in ISTA's public filings with the U.S. Securities and Exchange Commission, including but not limited to ISTA's Annual Report on Form 10-K for the year ended December 31, 2006, and ISTA's Quarterly Report on Form 10-Q for the quarter ended March 31, 2007.

CONTACT: Vince Anido, Ph.D., +1-949-788-5311, , orLauren Silvernail, +1-949-788-5302, , both ofISTA Pharmaceuticals; Investors: Juliane Snowden, , orNicki Kahner, ; Media: Jason Farber,, or Kristin Faucette, , all ofBurns McClellan, +1-212-213-0006, for ISTA Pharmaceuticals vanido@istavision.com lsilvernail@istavision.com jsnowden@burnsmc.com nkahner@burnsmc.com jfarber@burnsmc.com kfaucette@burnsmc.com

Web site: http://www.istavision.com/

Ticker Symbol: (NASDAQ-NMS:ISTA)

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