unodrugTM candidates are developed both in-house and together
with Novartis and Pfizer Animal Health. Founded in 1995 as a
spin-off from the Swiss Federal Institute of Technology (ETH) in
Zurich, the company is located in Schlieren (Zurich). Currently,
the company has 130 employees. Cytos Biotechnology AG has been
listed on the SWX Swiss Exchange (SWX:CYTN) since October
2002.
References
1 American Journal of Hypertension (2007), 20:587.
2 New England Journal of Medicine (1985), 313:1315.
3 Hypertension (2006), 47:149.
4 Hypertension Research (2006), 29:581.
5 American Journal of Hypertension (2004), 17:347.
6 World Health Organization, Atlas of Heart Disease and Stroke
(2004).
7 National Institute for Health and Clinical Excellence (NICE),
Centre for Health Services Research, UK; Essential
hypertension: managing adult patients in primary care (August
2004).
Glossary
Ambulatory blood pressure: blood pressure measured continuously
during a normally active day; takes numerous automatic readings
over a
24-hour period or longer and applies non-invasive ambulatory blood
pressure monitoring devices.
Angiotensin II: a molecule of the RAS inducing vasoconstriction of
blood vessels and other effects to raise blood pressure.
Antibody: class of blood proteins generated by the immune system to
bind and neutralize foreign materials such as bacteria or viruses.
Can
also be directed against the body’s own disease-associated
molecules (e.g. angiotensin II).
Antihypertensive drugs: a class of drugs used for treatment of high
blood pressure.
Asymptomatic: without symptoms.
Booster injection: refers to a vaccination given after a pervious
vaccination. Helps to maintain or increase an immune
response.
Cardiovascular events: refer to conditions affecting the
cardiovascular system, which comprises the heart, the blood
vessels, and the cells
and plasma that
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