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Human Genome Sciences Reports Growing Evidence That Its TRAIL,Receptor Antibodies Have Significant Potential in the Treatment of,a Broad Range of Cancers

any's web site at http://www.hgsi.com. To view the Journal of Clinical Oncology article reporting the results of the Phase 1 trial of HGS-ETR1, click here. To view the editorial that accompanied the Journal of Clinical Oncology article, click here. To view the AACR 2007 oral presentation of research results to date for the HGS TRAIL receptor antibodies, click here. To view the AACR 2007 poster presentation regarding bortezomib sensitization of TRAIL-R mAb-resistant NSCLC tumor cell lines, click here. Health professionals or patients interested in HGS-ETR1 or HGS-ETR2 clinical trials or other studies involving HGS products may inquire via the Contact Us section of the Company's web site, http://www.hgsi.com/products/request.html, or by calling us at (301) 610-5790, extension 3550.

Safe Harbor Statement

This announcement contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. The forward-looking statements are based on Human Genome Sciences' current intent, belief and expectations. These statements are not guarantees of future performance and are subject to certain risks and uncertainties that are difficult to predict. Actual results may differ materially from these forward-looking statements because of the Company's unproven business model, its dependence on new technologies, the uncertainty and timing of clinical trials, the Company's ability to develop and commercialize products, its dependence on collaborators for services and revenue, its substantial indebtedness and lease obligations, its changing requirements and costs associated with facilities, intense competition, the uncertainty of patent and intellectual property protection, the Company's dependence on key management and key suppliers, the uncert
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