Navigation Links
Genzyme Announces Results of Clinical Trials Investigating Powder,Form of Sevelamer Carbonate

CAMBRIDGE, Mass., June 18, 2007 /PRNewswire-FirstCall/ -- Genzyme Corp. today announced the results of two new studies comparing a powder form of Renvela (sevelamer carbonate) to Renagel tablets (sevelamer hydrochloride), including one trial in which patients received the powder form three times per day, and one in which it was administered once per day.

Genzyme is developing Renvela in powder form to provide an additional option for patients with chronic kidney disease in managing their phosphate levels. A New Drug Application for Renvela tablets is already on file with the FDA, and previous studies have shown that the tablet formulation provides equivalent phosphate control to Renagel in patients on dialysis and significant phosphorus control in patients with chronic kidney disease who are not on dialysis. Today's results are the first from trials comparing the efficacy of the powder form of Renvela to Renagel tablets.

In the first powder trial, patients treated with the powder form of Renvela three times per day experienced equivalent phosphorus control to patients treated with Renagel tablets three times per day. As a result, this trial successfully met its primary endpoint.

In the second trial, patients dosed with the powder form of Renvela once per day and those treated with Renagel tablets three times per day achieved statistically significant reductions in serum phosphorus, with both groups reaching target levels for phosphorus control outlined in the K/DOQI treatment guidelines. Phosphorus levels in the Renagel arm (4.6 mg/dL) were lower than those in the Renvela arm (5.3 mg/dL), and this trial did not achieve its primary endpoint of demonstrating non-inferiority of Renvela powder dosed once per day to Renagel tablets dosed three times per day.

In both trials, the safety profile of Renvela was consistent with the previous clinical experience of patients on dialysis using Ren
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
2. Genzyme Announces Results of Clinical Trial of Hylastan
3. Genzyme Announces Results of Clinical Trials Investigating Powder Form of Sevelamer Carbonate
4. Genzyme and Bayer HealthCare Announce Detailed Interim Two-Year Alemtuzumab in Multiple Sclerosis Data Presented at AAN
5. Genzyme Announces Successful Completion of Study Investigating Sevelamer Carbonate in Patients With Chronic Kidney Disease
6. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
7. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
8. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
9. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
10. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
11. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
Post Your Comments:
(Date:7/1/2015)... 1, 2015 According to a ... by Product (Natural & Synthetic, Fibrin, Collagen, Gelatin, Cyanoacrylate, ... - Global Forecast to 2020", published by MarketsandMarkets, the ... reach $2.64 Billion by 2020, growing at a CAGR ... Browse 119 market T ables ...
(Date:7/1/2015)... July 1, 2015 Prismic Pharmaceuticals, Inc., a ... medical foods, today announced the election of Joseph ... to its Board of Directors. Commenting on ... Peter Moriarty , Chairman and CEO of Prismic, stated, ... Martin Simonetti have accepted our invitation to ...
(Date:7/1/2015)... , July 1, 2015 Dynatronics ... manufacturer and marketer of rehabilitation and physical therapy ... $4,025,000 private placement financing led by affiliates of ... equity investor focused on the healthcare industry. The ... organic growth and pursue potential strategic acquisitions.  ...
Breaking Medicine Technology:Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 2Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 3Surgical Sealants and Adhesives Market Worth $2.64 Billion by 2020 4Joseph Krivulka and Martin Simonetti Join Board of Prismic Pharmaceuticals 2Dynatronics Announces Completion Of $4,025,000 Private Placement Led By Prettybrook Partners 2Dynatronics Announces Completion Of $4,025,000 Private Placement Led By Prettybrook Partners 3
... , HELSINKI, Dec. 14 Cancer patients in Finland ... of RapidArc® radiotherapy technology from Varian Medical Systems (NYSE: ... the Nordic region. Clinicians at Docrates Clinic in Helsinki are ... patients with multiple brain metastases and cancers of the abdomen ...
... , WALTHAM, Mass., Dec. 14 According to ... market intelligence, increased use of safety devices for small-bore connectors ... of the enteral feeding device markets in both the US ... Enteral Feeding Devices 2010 report finds that the giving ...
Cached Medicine Technology:Cancer Patients in Finland Gain Access to Advanced RapidArc Radiotherapy Treatments 2Cancer Patients in Finland Gain Access to Advanced RapidArc Radiotherapy Treatments 3Enteral Feeding Device Market To Generate More Than $700 Million in the US & Europe by 2014 2Enteral Feeding Device Market To Generate More Than $700 Million in the US & Europe by 2014 3
(Date:7/1/2015)... ... July 01, 2015 , ... ... exclusively to funding innovative lymphoma research and serving the lymphoma community through a ... that they will welcome four new members to their industry leading Scientific Advisory ...
(Date:7/1/2015)... Chesapeake, VA (PRWEB) , ... July 01, 2015 , ... ... interviewed on Monday, July 6th on WAVY-TV’s The Hampton Roads Show to discuss non-invasive ... results where diet and exercise fall short. , CoolSculpting fat reduction utilizes Cryolipolysis ...
(Date:7/1/2015)... ... 01, 2015 , ... During the first week of June, ... and Development) and Chuck Corso (Associate Sales Trainer) participated in the 44th Annual ... together learning and development professionals from more than 300 life sciences companies around ...
(Date:7/1/2015)... ... July 01, 2015 , ... Convoy of Hope ... in the Twin Cities on Saturday, August 1, at Spring Lake Park High School. ... provide more than $1 million worth of goods and services including free food, health ...
(Date:7/1/2015)... ... 01, 2015 , ... Element Blue ™, a leading ... it has received trademark protection for its SensorInsight® computer software platform. SensorInsight® is ... multiple sources providing an environment where users can view and compare real-time and ...
Breaking Medicine News(10 mins):Health News:Lymphoma Research Foundation Welcomes New Scientific Advisory Board Members 2Health News:Lymphoma Research Foundation Welcomes New Scientific Advisory Board Members 3Health News:Lymphoma Research Foundation Welcomes New Scientific Advisory Board Members 4Health News:Lymphoma Research Foundation Welcomes New Scientific Advisory Board Members 5Health News:Dr. Surya Challa of Chesapeake Vein Center and MedSpa Will be Featured on The Hampton Roads Show on WAVY-TV 2Health News:Dr. Surya Challa of Chesapeake Vein Center and MedSpa Will be Featured on The Hampton Roads Show on WAVY-TV 3Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 2Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 3Health News:Mission Pharmacal Company: Alamo Pharma Services' Training Leaders Take Steps to Further Expand Capabilities for Mission Pharmacal and Other Clients 4Health News:Convoy of Hope Hosts Community Event in the Twin Cities 2Health News:Element Blue Receives Trademark Protection from U.S. Patent and Trademark Office for Its Award Winning SensorInsight® Software 2Health News:Element Blue Receives Trademark Protection from U.S. Patent and Trademark Office for Its Award Winning SensorInsight® Software 3Health News:Element Blue Receives Trademark Protection from U.S. Patent and Trademark Office for Its Award Winning SensorInsight® Software 4
... direct marketing promotional products company, offers a specialty store filled ... ... Lewiston, ME (PRWEB) February 19, 2009 -- Crestline ... that trades on its easy, customer-friendly ordering process, offers ...
... Natrecor for a Use Not Approved By the Food ... has intervened in two whistleblower suits filed in the ... Inc. and its parent company, Johnson & Johnson Inc., ... for a use not approved by the Food and ...
... Indicates a 40% Reduction of Intraocular Pressure at Two ... today that it has surpassed 1000 implantation procedures with ... reduces intraocular pressure (IOP) for the treatment of glaucoma. ... President and Founder of SOLX, "as it validates the ...
... to Consumer-Directed Health Plans Continues, Watson Wyatt/National Business Group ... expect health care cost increases to hold steady at ... plans (CDHPs) in 2010 in an effort to control ... Wyatt, a leading global consulting firm, and the National ...
... to risk-taking, too, study finds, , , THURSDAY, Feb. ... makes people love skydiving, mountain-climbing or other intense ... the brain that has been linked to addictive ... researchers studied volunteers who were grouped as either ...
... percent less likely than men to receive a critical ... stroke, according to a Michigan State University study. , ... Diego at the International Stroke Conference, organized by the ... plasminogen activator, or tPA, first approved as a treatment ...
Cached Medicine News:Health News:Crestline is the Source for Great Green Giveaways 2Health News:Crestline is the Source for Great Green Giveaways 3Health News:United States Joins Suits Against Scios and Johnson & Johnson 2Health News:United States Joins Suits Against Scios and Johnson & Johnson 3Health News:SOLX Announces 1000th Gold Shunt Implantation Milestone for Glaucoma Treatment 2Health News:Health Care Benefit Cost Increases to Remain at 6 Percent in 2009 2Health News:Health Care Benefit Cost Increases to Remain at 6 Percent in 2009 3Health News:Thrill-Seekers' Brains May Be Wired Differently 2Health News:Women less likely to receive critical care after a stroke, MSU researchers find 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: