Navigation Links
Genzyme Announces Results of Clinical Trials Investigating Powder,Form of Sevelamer Carbonate

CAMBRIDGE, Mass., June 18, 2007 - Genzyme Corp. (Nasdaq: GENZ) today announced the results of two new studies comparing a powder form of Renvela™ (sevelamer carbonate) to Renagel® tablets (sevelamer hydrochloride), including one trial in which patients received the powder form three times per day, and one in which it was administered once per day.

Genzyme is developing Renvela in powder form to provide an additional option for patients with chronic kidney disease in managing their phosphate levels. A New Drug Application for Renvela tablets is already on file with the FDA, and previous studies have shown that the tablet formulation provides equivalent phosphate control to Renagel in patients on dialysis and significant phosphorus control in patients with chronic kidney disease who are not on dialysis. Today’s results are the first from trials comparing the efficacy of the powder form of Renvela to Renagel tablets.

In the first powder trial, patients treated with the powder form of Renvela three times per day experienced equivalent phosphorus control to patients treated with Renagel tablets three times per day. As a result, this trial successfully met its primary endpoint.

In the second trial, patients dosed with the powder form of Renvela once per day and those treated with Renagel tablets three times per day achieved statistically significant reductions in serum phosphorus, with both groups reaching target levels for phosphorus control outlined in the K/DOQI treatment guidelines. Phosphorus levels in the Renagel arm (4.6 mg/dL) were lower than those in the Renvela arm (5.3 mg/dL), and this trial did not achieve its primary endpoint of demonstrating non-inferiority of Renvela powder dosed once per day to Renagel tablets dosed three times per day.

In both trials, the safety profile of Renvela was consistent with the previous clinical experience of patients on dialysis
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
2. Genzyme Announces Results of Clinical Trial of Hylastan
3. Genzyme Announces Results of Clinical Trials Investigating Powder Form of Sevelamer Carbonate
4. Genzyme and Bayer HealthCare Announce Detailed Interim Two-Year Alemtuzumab in Multiple Sclerosis Data Presented at AAN
5. Genzyme Announces Successful Completion of Study Investigating Sevelamer Carbonate in Patients With Chronic Kidney Disease
6. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
7. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
8. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
9. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
10. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
11. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
Post Your Comments:
(Date:4/20/2015)... 2015   Precision Image Analysis (PIA) is ... advances in cardiovascular imaging and post-processing. Scott D. ... Society for Cardiovascular Magnetic Resonance (SCMR) will be ... patient management by providing broader access to Cardiac MRI ... to better understand appropriate use of CMR, the strengths ...
(Date:4/20/2015)... April 20, 2015  Sigma-Aldrich Corporation (Nasdaq: ... (CR) Magazine,s list of the 100 Best Corporate ... corporate responsibility performance.  Sigma-Aldrich ranked fifth, its highest ... the list. "We are honored to ... efforts and we are extremely pleased with our ...
(Date:4/20/2015)... N.J. , April 20, 2015  Johnson & ... of its Pharmaceutical business for the investment community beginning ... 2015 at the Hyatt Regency Hotel in ... approximately 3:00 p.m. Paul Stoffels , ... Joaquin Duato , Worldwide Chairman, Pharmaceuticals will host ...
Breaking Medicine Technology:Educational Webinar Teaches Improved Patient Management Through Broader Access to Cardiac MRI 2Sigma-Aldrich Named to CR Magazine's 100 Best Corporate Citizens List 2
... Actavis, an international generic pharmaceutical company, today announced that ... CII, an authorized generic of KADIAN®*. Actavis ... in-depth expertise in the development and manufacturing of complex ... grown 50% in the last 5 years to approximately ...
... Lotus Pharmaceuticals, Inc. (OTCBB: LTUS) ("Lotus" or the "Company"), ... in the People,s Republic of China ("PRC"), today announced its ... 2011. Summary financial data is provided below: ... Highlights Revenues for the third quarter of ...
Cached Medicine Technology:Actavis Launches Generic KADIAN® Capsules in the U.S. 2Lotus Pharmaceuticals Announces Third Quarter 2011 Financial Results 2Lotus Pharmaceuticals Announces Third Quarter 2011 Financial Results 3Lotus Pharmaceuticals Announces Third Quarter 2011 Financial Results 4Lotus Pharmaceuticals Announces Third Quarter 2011 Financial Results 5Lotus Pharmaceuticals Announces Third Quarter 2011 Financial Results 6
(Date:4/21/2015)... NOVAtime Technology, Inc. ( http://www.novatime.com ... Attendance / Workforce Management solutions, announced its participation ... Payroll Association (APA) as well as NetSuite’s SuiteWorld ... been the nation’s payroll authority since 1982, and ... recertification credits. Held at the MGA Grand in ...
(Date:4/21/2015)... (PRWEB) April 21, 2015 Nashville, ... services and provider of Picture Archiving and Communication ... with four new installations in the first quarter ... KY), Pinnacle Orthopaedics (McMinnville, TN) and Lowcountry Orthopaedics ... ProtonPACS viewer and data archiving services. Mt. San ...
(Date:4/21/2015)... Angeles, CA (PRWEB) April 21, 2015 ... power score of 3.8 out of 5, indicating generally ... due to its low barriers to entry and the ... are only moved relatively short distances,” says IBISWorld research ... scattered throughout the country, typically serving local and regional ...
(Date:4/21/2015)... 2015 Lifeguard Master is out with their ... are listed on the Lifeguard Master website and are in ... who want a quality and flexible product during their rescue ... and color Spider Straps are some of the most popular ... of sturdy, heavy nylon” , The Spider Straps are rated ...
(Date:4/21/2015)... Dr. Zain Kadri, a Beverly Hills plastic surgery ... a close look at the rise of plastic surgery among ... both Dr. Kadri’s website and RedOrbit , is titled ... of the Selfie.” According to Dr. Kadri, who offers exceptional ... of A-list patients, the trend of taking selfies has been ...
Breaking Medicine News(10 mins):Health News:NOVAtime Participates in 2015 APA Congress and NetSuite SuiteWorld Conferences in May 2Health News:NOVAtime Participates in 2015 APA Congress and NetSuite SuiteWorld Conferences in May 3Health News:Radsource Adds 4 ProtonPACS Clients in 1st Quarter 2Health News:Bulk Food-Grade Transportation Services Procurement Category Market Research Report from IBISWorld has Been Updated 2Health News:Bulk Food-Grade Transportation Services Procurement Category Market Research Report from IBISWorld has Been Updated 3Health News:New Spider Straps for Spine Boards are Introduced for Easy, Fast, and Convenient Use 2Health News:New Spider Straps for Spine Boards are Introduced for Easy, Fast, and Convenient Use 3Health News:New Spider Straps for Spine Boards are Introduced for Easy, Fast, and Convenient Use 4Health News:Beverly Hills Plastic Surgery Expert Dr. Zain Kadri Releases Thought-Provoking New Infographic 2
... in study , , TUESDAY, May 5 (HealthDay News) -- ... more aware of the potentially disabling or fatal consequences ... pressure, new research has found. , The study included ... They all wore portable monitors that took 24-hour blood ...
... PITTSBURGHA new study out of the University of Pittsburgh suggests ... wandering, while at the same time reducing the likelihood of ... "Lost in the Sauce: The Effects of Alcohol on Mind ... issue of Psychological Science . , The study ...
... Medical Officer for the Keystone Peer Review Organizations, Inc. (KePRO), an ... speaker at the 15th Annual MEDecision User Conference to be held ... ... (Vocus) May 5, 2009 -- Alice Stollenwerk Petrulis, MD, FACP, Chief ...
... DIEGO, May 5 ResMed Inc. (NYSE: RMD ) ... conferences. Kieran Gallahue, President and CEO will present at the Bank ... York Palace Hotel in New York City on May 13, 2009 ... Development and General Counsel will present at the Deutsche Bank Health ...
... Company also announces launch of Ohiomedicalnpwt.comGURNEE, Ill., May ... MoblVac(R) portable wound care pump system with TruSeal(TM) ... at the annual meeting of the Advanced Wound ... Grapevine, TX last week. Reaction was extremely positive ...
... pamphlet offers answers and resources to help patients advocate ... the director for the Arizona Department of Insurance and ... free pamphlet developed to educate patients about the rights ... a press conference last Thursday on the Senate Lawn ...
Cached Medicine News:Health News:Phone Monitoring May Help Lower Blood Pressure 2Health News:Pitt study on alcohol reveals drinkers not only zone out -- but also are unaware that they do 2Health News:Alice Stollenwerk Petrulis, MD, FACP, to Speak at 15th Annual MEDecision User Conference 2Health News:Alice Stollenwerk Petrulis, MD, FACP, to Speak at 15th Annual MEDecision User Conference 3Health News:Ohio Medical Corporation(R) Launches MoblVac(R), a Portable Pump System for Negative Pressure Wound Therapy 2Health News:Sen. Carolyn Allen Calls for Patient Rights and Treatment Option Awareness 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: