The presentation will be webcast live and can be accessed by logging onto www.gtc-bio.com. The replay can be accessed from this same website and will be available within 24 hours of the presentation.
About GTC Biotherapeutics
GTC Biotherapeutics develops, produces, and commercializes therapeutic proteins through transgenic animal technology. ATryn(R), GTC's recombinant form of human antithrombin, is approved by the European Commission for use in patients with hereditary antithrombin deficiency undergoing surgical procedures. This was the first approval anywhere in the world of a therapeutic protein produced from a transgenic animal.
LEO Pharma A/S, ATryn(R)'s commercial and development partner in Europe, Canada, and the Middle East, is in the process of launching in the approved indication and recruiting patients into a Phase II dose ranging study for the treatment of disseminated intravascular coagulation associated with severe sepsis. GTC is conducting a Phase III study of ATryn(R) for use in the United States in hereditary antithrombin deficiency patients undergoing high risk surgical and childbirth procedures. In addition, GTC has established a strategic collaboration with LFB Biotechnologies of France to jointly develop recombinant forms of human plasma proteins and monoclonal antibodies. The first program of the collaboration will be to develop recombinant human factor VIIa as a potential treatment for hemophilia in patients with antibodies to other coagulation factors.
In 2006, GTC was granted a patent in the United States through 2021 for the production of any therapeutic protein in the milk of any transgenic mammal. GTC's transgenic production platform is particularly well suited to enabling cost effective development of proteins that are difficult to express in traditional recombinant production systems as well as those that are required in large volumes at a competitive cost. Additional information is available on the GTC web site, http://www.gtc-bio.com.
GTC Biotherapeutics, Inc.
Thomas E. Newberry
Vice President, Corporate Communications
Feinstein Kean Healthcare for GTC Biotherapeutics, Inc.