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GSK'S Pazopanib Shows Positive Results in Patients with Advanced,Renal Cell Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

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Cautionary statement regarding forward-looking statements

Under the safe harbor provisions of the U.S. Private Securities Litigation Reform Act of 1995, the company cautions investors that any forward-looking statements or projections made by the company, including those made in this announcement, are subject to risks and uncertainties that may cause actual results to differ materially from those projected. Factors that may affect the Group's operations are described under 'Risk Factors' in the Operating and Financial Review and Prospects in the company's Annual Report on Form 20-F for 2005.


    Notes to editors:

TYKERB(R) is a registered trademark of the GlaxoSmithKline group of companies

in the United States. To access the latest GSK Oncology media materials, visit

http://www.gsk.com


    Enquiries:

    On-site at ASCO                       Robin Fastenau 1 919 522 5237

    US Media enquiries:                   Mary Anne Rhyne 1 919 483 2839


    UK Media enquiries:                   Philip Thomson 44 20 8047 5502

                                          Alice Hunt 44 20 8047 5502

                                          Gwenan White 44 20 8047 5502


    European Analyst/Investor enquiries:  Anita Kidgell 44 20 8047 5542

                                          Sally Ferguson 44 20 8047 5543

                                          David Mawdsley 44 20 8047 5564


    US Analyst/ Investor enquiries:       Frank Murdolo 1 215 751 7002

                                          Tom Curry 1 215 751 5419


    References:

    (1)  Sonpavde, G. and Hutson, T. Pazopanib: A Novel Multitargeted Tyrosine

         Kinase Inhibitor. Curr Oncol Rep. 2007; Mar;9(2):115-9

    (2)  Jain RK. Antiangiogenic therapy for cancer: current and emerging

         concepts. Oncology. 2005 Apr;19(4 Suppl 3):7-16

    (3)  Hutson, T. E., Davis I. D., et al. Pazopanib (GW786034) is active 
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