Navigation Links
Fragile X, Down Syndromes Linked to Faulty Brain Communication,,Stanford Researcher Finds

STANFORD, Calif.--(BUSINESS WIRE)--Apr 10, 2007 - The two most prevalent forms of genetic mental retardation, Fragile X and Down syndromes, may share a common cause, according to researchers at Stanford University School of Medicine. The problem, a crippled communication network in the brain, may also be associated with autism.

Although the genetics of the disorders are very different, the end result for the brain seems to be the same, said Daniel Madison, PhD, associate professor of molecular and cellular physiology. "It's as if you had every light in your house wired to just one or two switches, rather than having many switches that can be flipped on or off in complex combinations to control the lighting in one room," he said.

Madison is the senior author of a paper on Fragile X syndrome in mice, which will be published in the April 11 issue of the Journal of Neuroscience. He published a related study on mice with Down syndrome symptoms in the Feb. 15 issue of the Journal of Physiology.

Madison is a member of Stanford's Down Syndrome Research Center, started in 2003 by researchers at the School of Medicine and Lucile Packard Children's Hospital to accelerate the application of research to effective treatments for the condition.

In the latest study, Madison and postdoctoral scholar Jesse Hanson, PhD, studied Fragile X syndrome, which is a leading cause of mental retardation in this country. Affected people tend to have learning disabilities, distinct physical characteristics such as enlarged ears and a long face, and such behavioral problems as attention deficit disorder, speech disturbances and unusual responses to various sights or sounds. Although it's not known why, about one-third of people with Fragile X also develop autism--a much higher percentage than in the general population. This makes Fragile X, which can be studied in mice, the only genetic model for autism.

As the syn
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes
2. Study Continues to Show Patients With Myelodysplastic Syndromes Treated With Revlimid are Living Longer and Remaining Transfusion Independent
3. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
4. Diabetes Linked to Higher Parkinsons Risk
5. Samaritans Alzheimers Drug Caprospinol Suggests Brain May be Able to Heal From Alzheimers Disease
6. Stanford Researchers Find Brain Pathway of Depression in Rats
7. Suven Life Sciences Presenting Pre-clinical data of their NCE’s SUVN-502 and SUVN-507at International Brain Research Organization (IBRO) 2007 World Congress of Neuroscience
8. Allos Therapeutics Reports Results for Phase 3 Enrich Study of Efaproxyn in Women With Brain Metastases Originating From Breast Cancer
9. Stanford Researchers Track Human Stem Cells Transplanted Into Rat Brain
10. Phase 2 Results for EntreMeds Panzem NCD Brain Cancer Study Presented at ASCO
11. Merck at ASCO 2007: Encouraging Results in Progression-Free Survival in Patients With Aggressive Brain Tumors (glioblastoma) Using Cilengitide in Phase I/IIa Study
Post Your Comments:
(Date:8/28/2015)... , Aug. 28, 2015  IP Shakti, LLC, today ... Logo - ... "Our new corporate identity signifies our transformation into ... first predictive analytics platform for patent claim validity." ... launch of the proprietary AIA Shield™ platform, the Company commenced ...
(Date:8/28/2015)... PITTSBURGH , Aug. 28, 2015 ... announced that its shareholders have approved Mylan,s proposed ... ; TASE) and the related issuance of Mylan ... general meeting of shareholders held today. The transaction ... the extraordinary general meeting. In addition, the transaction ...
(Date:8/28/2015)... and LONDON , August 28, 2015 ... approach seamlessly connects people, technologies ... improving outcomes and the cost of ... PHG AEX: PHIA) today announced its presence at  ESC Congress ... solutions, including Heart Model A.I. , EchoNavigator and IntelliSpace Cardiovascular, ...
Breaking Medicine Technology:IP Shakti, LLC Changes Company Name to Prediqtus, LLC 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 2Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 3Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 4Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 5Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 6Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 7Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 8Mylan Shareholders Overwhelmingly Approve Proposed Acquisition of Perrigo 9Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 2Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 3Philips Showcases New Integrated Cardiology Solutions to Advance Minimally Invasive Procedures at ESC Congress 2015 4
... March 17, 2011 A recently issued patent ... award winning and best selling medical thermometer brand, ... recently been granted U.S. Patent No. 7,787,938, entitled, ... and Trademark Office, adding to the already extensive ...
... VEGAS, March 17, 2011 A new study by Craig ... and North Cypress Medical Center in Houston, presented this week ... the improved photon sensitivity of new detector technologies such as ... dose patient receive from BSGI/MBI studies by 75%.  However, low ...
Cached Medicine Technology:Exergen Granted New Patent for Temporal Artery Thermometers 2New Technologies Open the Door for Low Dose Breast-Specific Gamma Imaging (BSGI) / Molecular Breast Imaging (MBI) 2
(Date:8/28/2015)... ... August 28, 2015 , ... As reported by Medical Daily on ... clearance for results that last for two years, the longest of any cellulite reduction ... are looking for a long-lasting, effective solution for their cellulite, according to Dr. Robert ...
(Date:8/28/2015)... ... August 28, 2015 , ... On May 30th, 2015, Best Drug ... of the “Music With A Mission” benefit concert in Mendon, IL. Held in the ... raise money to support music education programs in the underfunded local school districts of ...
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... ... 20 grams of high grade protein with zero fat, carbs, sugar, gluten, lactose ... been named a finalist for the 2015 SupplySide CPG Editor’s Choice Awards. , ...
(Date:8/28/2015)... ... August 28, 2015 , ... Altima Technologies, Inc., the ... and data center assets and audio-video devices, recently released Visio Stencils for the ... HP ProLiant Gen9, EMC VNX Series , Super Micro Computer SuperStorage, Hitachi Data ...
(Date:8/28/2015)... ... 2015 , ... Medical Solutions, one of the nation’s largest travel nurse staffing ... by Modern Healthcare and will be honored at an awards dinner in Chicago ... Best Places to Work in Healthcare program recognizes outstanding employers in the healthcare industry ...
Breaking Medicine News(10 mins):Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 2Health News:Maryland Dermatologists Discuss Non-Invasive Cellulite Reduction System Cellfina Receiving 2-Year FDA Clearance 3Health News:New Video Released on "Music With A Mission" Benefit Concert Headlining Artist Cadillac Three & Best Drug Rehabilitation 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 2Health News:Altima Updates NetZoom™ Visio® Stencil Library for Cisco, HP, and EMC Devices 3Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 2Health News:Medical Solutions Recognized as One of 2015 Best Places to Work in Healthcare 3
... Buffalo scientists have paired up to create technology ... worldwide, developing the first procedure-based, hands-on surgical training ... (HOST), guides surgeons through real-time operative procedures using ... Khurshid Guru, MD, a staff physician in Urology ...
... targeted monoclonal antibodies in combination with existing therapies show ... according to research that will be presented by investigators ... the 2010 meeting of the American Society of Clinical ... antibody to enhance the effectiveness of a breast cancer ...
... ... explosion of celebrity sex tapes and scandals, including the recent release of Kendra Wilkinson,s ... ... the explosion of celebrity sex tapes and scandals, including the recent release of Kendra ...
... ... of all ages active , ... Monica, CA (PRWEB) June 1, 2010 -- Leading youth fitness brand O2 MAX Fitness ... teenagers, and children ranging from ages 2 to early 20s. As with all of their past ...
... against cerebral malaria, a fatal form of malaria in children ... treat. New research points to platelets known for their ... in the disease, stimulating the immune system and turning on ... of blood vessels in the brain, causing brain damage similar ...
... ... ... June 1, 2010 -- Check In Systems, Inc., a leading provider of check ... enhancements to its Medical Check In HIPAA-compliant patient registration kiosk solution. “Medical Check In ...
Cached Medicine News:Health News:Surgeon-engineer team produce training software for robot-assisted surgery 2Health News:Targeted immunotherapy shows promise for metastatic breast, pancreatic cancers 2Health News:Targeted immunotherapy shows promise for metastatic breast, pancreatic cancers 3Health News:Targeted immunotherapy shows promise for metastatic breast, pancreatic cancers 4Health News:Kendra Wilkinson's Sex Tape Raises Awareness About STDs 2Health News:O2 MAX Fitness Announces "90 Days to Healthy" and Unveils a Summer Slate Full of Youth-Oriented Fitness Initiatives 2Health News:O2 MAX Fitness Announces "90 Days to Healthy" and Unveils a Summer Slate Full of Youth-Oriented Fitness Initiatives 3Health News:Rochester advances understanding of deadly form of malaria 2Health News:Rochester advances understanding of deadly form of malaria 3Health News:Check In Systems Enhances Patient Registration Solution 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: