Navigation Links
Fragile X, Down Syndromes Linked to Faulty Brain Communication,,Stanford Researcher Finds

STANFORD, Calif.--(BUSINESS WIRE)--Apr 10, 2007 - The two most prevalent forms of genetic mental retardation, Fragile X and Down syndromes, may share a common cause, according to researchers at Stanford University School of Medicine. The problem, a crippled communication network in the brain, may also be associated with autism.

Although the genetics of the disorders are very different, the end result for the brain seems to be the same, said Daniel Madison, PhD, associate professor of molecular and cellular physiology. "It's as if you had every light in your house wired to just one or two switches, rather than having many switches that can be flipped on or off in complex combinations to control the lighting in one room," he said.

Madison is the senior author of a paper on Fragile X syndrome in mice, which will be published in the April 11 issue of the Journal of Neuroscience. He published a related study on mice with Down syndrome symptoms in the Feb. 15 issue of the Journal of Physiology.

Madison is a member of Stanford's Down Syndrome Research Center, started in 2003 by researchers at the School of Medicine and Lucile Packard Children's Hospital to accelerate the application of research to effective treatments for the condition.

In the latest study, Madison and postdoctoral scholar Jesse Hanson, PhD, studied Fragile X syndrome, which is a leading cause of mental retardation in this country. Affected people tend to have learning disabilities, distinct physical characteristics such as enlarged ears and a long face, and such behavioral problems as attention deficit disorder, speech disturbances and unusual responses to various sights or sounds. Although it's not known why, about one-third of people with Fragile X also develop autism--a much higher percentage than in the general population. This makes Fragile X, which can be studied in mice, the only genetic model for autism.

As the syn
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes
2. Study Continues to Show Patients With Myelodysplastic Syndromes Treated With Revlimid are Living Longer and Remaining Transfusion Independent
3. Algeta Demonstrates Targeted Cancer-killing Potential of Novel Alpha Particle Linked Antibodies in Leading Medical Journal Blood
4. Diabetes Linked to Higher Parkinsons Risk
5. Samaritans Alzheimers Drug Caprospinol Suggests Brain May be Able to Heal From Alzheimers Disease
6. Stanford Researchers Find Brain Pathway of Depression in Rats
7. Suven Life Sciences Presenting Pre-clinical data of their NCE’s SUVN-502 and SUVN-507at International Brain Research Organization (IBRO) 2007 World Congress of Neuroscience
8. Allos Therapeutics Reports Results for Phase 3 Enrich Study of Efaproxyn in Women With Brain Metastases Originating From Breast Cancer
9. Stanford Researchers Track Human Stem Cells Transplanted Into Rat Brain
10. Phase 2 Results for EntreMeds Panzem NCD Brain Cancer Study Presented at ASCO
11. Merck at ASCO 2007: Encouraging Results in Progression-Free Survival in Patients With Aggressive Brain Tumors (glioblastoma) Using Cilengitide in Phase I/IIa Study
Post Your Comments:
(Date:5/4/2015)... May 4, 2015  Neurocrine Biosciences, Inc. (NASDAQ: ... has joined the company as Vice President, Medical ... welcome Dr. Bill Aurora to the Neurocrine ... Kevin Gorman , President and Chief Executive Officer of ... exchange and outreach coupled with his extensive network and ...
(Date:5/4/2015)... May 4, 2015  Amgen (NASDAQ: AMGN ) will ... 8 a.m. ET on Thursday, May 7, 2015, at the ... Hooper , executive vice president of Global Commercial Operations at ... presentation can be accessed from the Events Calendar on Amgen,s ... webcast will also be available on Amgen,s website for 90 ...
(Date:5/4/2015)... , May 4, 2015 DePuy Synthes CMF* ... Repair, the first commercially available biosynthesized dural replacement derived ... is a part of the DePuy Synthes Companies of ... tissue membrane that covers and protects the brain and ... to allow surgeons to access the brain. A dural ...
Breaking Medicine Technology:Neurocrine Biosciences, Inc. Announces Appointment of Dr. Bill Aurora as Vice President, Medical Affairs 2Neurocrine Biosciences, Inc. Announces Appointment of Dr. Bill Aurora as Vice President, Medical Affairs 3Amgen To Present At The Deutsche Bank 40th Annual Healthcare Conference 2DePuy Synthes CMF Launches First Biosynthesized Cellulose-Based Dural Replacement For Neurosurgery 2DePuy Synthes CMF Launches First Biosynthesized Cellulose-Based Dural Replacement For Neurosurgery 3
... YORK, Jan. 10, 2011 Resolvyx Pharmaceuticals ( Resolvyx ... ), a successor firm to Celtic Pharma, announced today ... which Celtic Therapeutics has acquired and licensed worldwide rights ... treatment of dry eye syndrome and other ophthalmic conditions. ...
... 2011 Astellas Pharma Inc. (TSE: 4503) ... to conduct, in conjunction with executive management, a review of ... Prosidion was acquired as part of Astellas, acquisition of OSI ... two drug candidates in development for diabetes and obesity, as ...
Cached Medicine Technology:Resolvyx Pharmaceuticals and Celtic Therapeutics Enter Final Agreement in Ophthalmology 2Resolvyx Pharmaceuticals and Celtic Therapeutics Enter Final Agreement in Ophthalmology 3Resolvyx Pharmaceuticals and Celtic Therapeutics Enter Final Agreement in Ophthalmology 4Astellas to Review Strategic Business Alternatives for Prosidion Subsidiary 2Astellas to Review Strategic Business Alternatives for Prosidion Subsidiary 3
(Date:5/4/2015)... NY (PRWEB) May 04, 2015 ... insurance programs, announces the expansion of coverage for its ... a leading provider of industry-tailored insurance and proactive risk ... & Company, we are dedicated to providing our customers ... meet their many evolving needs. We are excited to ...
(Date:5/4/2015)... TROY Healthcare Solutions is proud to be a ... (RUG) Conference in Baltimore, MD from May 11 – ... provides an opportunity for clients to gather to network, ... In addition to sponsoring the event, TROY Healthcare Solutions ... Conference. Attendees can stop by the TROY booth and ...
(Date:5/4/2015)... May 04, 2015 Baptist Medical ... Stroke Association’s Get With The Guidelines®-Stroke Gold Plus ... Honor Roll. The award recognizes the hospital’s commitment ... the most appropriate treatment according to nationally recognized, ... , To receive the Gold Plus Quality Achievement ...
(Date:5/4/2015)... May 04, 2015 Now in its ... clinical leaders who have made outstanding contributions to the ... serve, both in acute and post-acute care settings. The ... Post-Acute Provider of the Year, Advanced Practice Clinician of ... Provider of the Year. Recipients are selected by IPC’s ...
(Date:5/4/2015)... May 04, 2015 Los Angeles ... offering a more comfortable and attractive alternative for patients ... choice for those who have lost teeth. Unfortunately, they ... insecure or slip at the worst possible moment and ... talks. They can also painfully pinch or rub gums, ...
Breaking Medicine News(10 mins):Health News:Insurance Leader McNeil & Company Expands Coverage for Emergency Services Insurance Program (ESIP), Launches Enhancements to Property and Casualty Insurance Package 2Health News:Insurance Leader McNeil & Company Expands Coverage for Emergency Services Insurance Program (ESIP), Launches Enhancements to Property and Casualty Insurance Package 3Health News:TROY Healthcare to Exhibit at the Cerner North Atlantic Regional User Group Conference 2Health News:TROY Healthcare to Exhibit at the Cerner North Atlantic Regional User Group Conference 3Health News:Baptist Medical Center Jacksonville Receives Top Honor for Stroke Care 2Health News:Baptist Medical Center Jacksonville Receives Top Honor for Stroke Care 3Health News:Baptist Medical Center Jacksonville Receives Top Honor for Stroke Care 4Health News:IPC Healthcare Announces Clinicians of the Year 2Health News:IPC Healthcare Announces Clinicians of the Year 3Health News:Los Angeles Dental Implants Doctor, Kevin Sands DDS, Now Offers a More Comfortable and Aesthetically-Pleasing Solution to Denture-Wearers 2
... , , WAYNE, Pa., July ... documentation software, workflow tools, consulting and staffing services has announced ... Marketing and Communications. Reporting directly to founder and CEO ... marketing initiatives that blend the strong brand of Precyse,s services ...
... , BATESVILLE, Ind., July 29 Hillenbrand, Inc. (NYSE: ... the market opens Wednesday, Aug. 12, 2009. The full text of ... site at www.HillenbrandInc.com . , , ... with investors and financial analysts the same day at 8 a.m. ...
... , CARLSBAD, Calif., July ... announced today that Cardiac Science Corporation has purchased a ... Group. Cardiac Science develops, manufactures, and markets ... and Holter systems, cardiac rehabilitation telemetry, and data management ...
... , , DARIEN, Conn., July 29 ... The Switch , a sparkling 100% juice, is expanding its availability ... Amazon.com, The Switch has added key retailers Tops, ... months. And the list of eager retailers keeps growing with Wegmans, ...
... , , CARMEL, Ind., ... announced that Christopher J. Foote has been promoted to vice president, ... in 1999 and served previously as senior managing actuary for asset-liability ... and shared actuarial services. , , ...
... , SAN DIEGO, July 29 ... solutions that can reach over 3.5 billion mobile phones globally, today announced ... industry leaders. , , Key Facts: , ... the 7-member advisory board is to provide Globaltel Media,s executive management team ...
Cached Medicine News:Health News:Precyse Solutions Taps Former Siemens Executive to Lead New Marketing Organization 2Health News:Hillenbrand Announces Third-Quarter Earnings Release Date and Conference Call 2Health News:Patriot Scientific Corporation Announces Cardiac Science Corporation's Purchase of a Moore Microprocessor Patent(TM) Portfolio License 2Health News:People Across the Country are Making The Switch! 2Health News:Globaltel Media Appoints Leading Healthcare Industry Veterans to Advisory Board 2Health News:Globaltel Media Appoints Leading Healthcare Industry Veterans to Advisory Board 3
The DePuy ACE 8.0mm Cannulated Cancellous Screw incorporates TiMAX to provide superior strength, fatigue resistance and a lower modulus of elasticity when compared to similar stainless steel devices....
Biomet® Arthrodesis Nail indications include: , Failed external fixation , Aseptic failed total knee arthroplasty , Periarticular fractures where repair is not possible , Limb salvage in tumor...
True hemostasis management is achieved with the Hepcon HMS PLUS Hemostasis Management System from Medtronic. This multi-purpose, intuitive system easily performs in-vitro diagnostic procedures....
An Innovative New System to Help You Meet the Challenges of Anterior Spine Surgery...
Medicine Products: