Navigation Links
First single breast cancer study to show significant survival,benefit for women switching from tamoxifen to Arimidex

Anastrozole (ArimidexTM) improves overall survival in postmenopausal women with early breast cancer receiving treatment with tamoxifen

– Survival benefit demonstrated for an AI over tamoxifen in a single trial –

LUTON, England, Friday 15 June 2007: Analysis of the entire population of a single trial has demonstrated that survival in early breast cancer can be significantly improved by switching from tamoxifen to anastrozole (ArimidexTM). An analysis of the ‘Arimidex’-‘Nolvadex’ 95 (ARNO 95) study, published online in The Journal of Clinical Oncology, confirms that postmenopausal women who have been taking tamoxifen as part of their treatment for early breast cancer for two years can significantly reduce the chance of their breast cancer returning by switching therapy to anastrozole. [i]

The ARNO 95 study, involving 979 patients, was designed to evaluate whether post-menopausal women with hormone-receptor positive early breast cancer who had been receiving endocrine treatment with tamoxifen for two years would benefit from switching to an aromatase inhibitor (AI). The study demonstrated that women switching to anastrozole (n=489) rather than remaining on tamoxifen (n= 490) experienced1:

· 34% reduction in the relative risk of recurrence (HR = 0.66; p=0.049)

· 47% improvement in overall survival (HR = 0.53; p=0.045)

· Fewer serious adverse events (22.7% v 30.8%) (OR = 0.66; p=0.0065)

“This new study is the first individual aromatase inhibitor trial showing a benefit in overall survival in the whole of the study population. The result is particularly striking in that this was a substantial group of patients with a relatively good prognosis (74% node negative). The reason that this result is so important is that improvement in overall survival is the biggest prize of all,” said Professor Jeffrey Tob
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
3. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
4. Ablynx Announces Interim Results of First Nanobody Phase I Study of ALX-0081 (ANTI-VWF)
5. Advanced Life Sciences Announces Supplemental Efficacy Data from First Pivotal Phase 3 Pneumonia Clinical Trial
6. Advanced Life Sciences to Host Conference Call to Discuss Data From Cethromycins First of Two Phase 3 Pneumonia Trials
7. First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes
8. Advanced Cell Technology Develops First Human Embryonic Stem Cell Line without Destroying an Embryo
9. First Demonstration of nanoImmunology: a Nanomaterials-based Therapeutic Approach to Treat Allergy
10. Mymetics HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model
11. Dasatinib Shows High Early Response Rate as First Treatment for Chronic Myelogenous Leukemia, M. D. Anderson Researchers Report
Post Your Comments:
(Date:7/11/2014)... , July 11, 2014 /PRNewswire-iReach/ -- VAPETEK™, ... a vegetable-glycol solution for use in portable vaporizers, ... the active ingredients in cannabis, cannabidiol offers consumers ... vaporizer devices, and other vaporizer technology. ... Cannabis naturally contains 483 different compounds which are ...
(Date:7/11/2014)... July 11, 2014 Patient engagement has ... consequently, organizations are turning to an assortment of ... As part of this evolving approach to patient ... communicate and engage patients throughout their experiences with ... empowerment. By mapping the patient journey and employing ...
(Date:7/11/2014)... July 11, 2014 The consumer marketing ... across industry sectors to better identify winning tools ... to engage with and understand consumers, as new ... make critical purchasing decisions. According ... LLC, one area where organizations can observe a ...
Breaking Medicine Technology:VAPETEK Releases CBD-Infused eLiquid For The Consumer Market 2New Study Uses Six-Step Patient Journey as Framework for Consumer-Focused Marketing Opportunities 2New Technologies Transforming Consumer Marketing Research Playbook 2
... Echo Therapeutics, Inc. (OTC Bulletin Board: ... System as a non-invasive, wireless, transdermal continuous glucose monitoring ... delivery, today announced that it is beginning a development ... continuous lactate monitoring to be used in critical care ...
... American Medical Systems® (AMS) (Nasdaq: ... therapies for both male and female pelvic health, today ... study of the Elevate® Apical and Posterior Prolapse Repair ... to quantify, describe, and stage pelvic support, was implemented ...
Cached Medicine Technology:Echo Therapeutics Initiates Needle-Free Biosensor Program for Continuous Lactate Monitoring 2Echo Therapeutics Initiates Needle-Free Biosensor Program for Continuous Lactate Monitoring 312-Month Study Reports Efficacy Rates for AMS' Elevate Apical and Posterior Prolapse Repair System 2
(Date:7/12/2014)... Recently, Fadhits.com, a well-known wedding dress manufacturer and ... graduation dresses to its product line. In addition, the ... It wants to bring more benefits for its loyal fans. ... discounted prices, up to 72% off. , As a leader ... Its online shop is a good place for ladies who ...
(Date:7/12/2014)... July 13, 2014 Recently, iFitDress.com, one of ... selection of red evening gowns . What’s more, all ... 56% off. , The company’s senior spokesman states, “We are ... on our website is an enjoyable shopping experience. In addition ... our online store, low prices do not always mean bad ...
(Date:7/12/2014)... 2014 The Chicken Egg Production ... five years, buoyed by stable demand for industry products ... “Eggs are a relatively affordable staple for most families ... generally grows in line with the size of the ... demand for new specialty egg products with enriched qualities, ...
(Date:7/12/2014)... Passenger Information System market is estimated to grow from ... at an expected CAGR of 26.5% for the period ... in North America is well developed and network infrastructure ... the region. The growing ridership figures in public transport ... driving the North American Passenger Information System market at ...
(Date:7/12/2014)... Fresh off their respective performances in the 2014 World Cup, ... at Sun Life Stadium in an international friendly. The World ... stars in the world of football in Colombian and Brazilian ... some of the best talent in the world in early ... team in the world according to the Fédération Internationale de ...
Breaking Medicine News(10 mins):Health News:New Collection of Long Graduation Dresses Revealed by Fadhits.com 2Health News:Discounted Red Evening Gown Announced by iFitDress.com 2Health News:Chicken Egg Production in Canada Industry Market Research Report Now Available from IBISWorld 2Health News:Chicken Egg Production in Canada Industry Market Research Report Now Available from IBISWorld 3Health News:North America Passenger Information System (ICT) Market worth $5,486.88 Million by 2019 - New Report by MicroMarket Monitor 2Health News:North America Passenger Information System (ICT) Market worth $5,486.88 Million by 2019 - New Report by MicroMarket Monitor 3Health News:North America Passenger Information System (ICT) Market worth $5,486.88 Million by 2019 - New Report by MicroMarket Monitor 4Health News:Brazil Vs. Colombia Tickets Sun Life Stadium: Ticket Down Slashes Ticket Prices for Friendly Match Between Colombia and Brazil 2Health News:Brazil Vs. Colombia Tickets Sun Life Stadium: Ticket Down Slashes Ticket Prices for Friendly Match Between Colombia and Brazil 3
... With Food Prices on the Rise New Tools to Help ... Personal finance expert Suze Orman,is the latest celebrity to join ... in their health. With rising food costs, many,families are economizing ... is nutrition. At about 25 cents per 8 ounce glass, ...
... Do Not Feel Knowledgeable About Their,Cancer Risks and Justifies ... and Entertain, LOS ANGELES, Sept. 29 Olympic ... and Nastia Liukin, along with Team USA,will join with ... national network,television special, Frosted Pink with a Twist, in ...
... in outcomes, but offers no concrete answers , , MONDAY, Sept. ... ZIP codes are more likely to die after surgery than ... research. , The study analyzed death rates among more than ... high-risk heart or cancer surgeries between 1999 and 2003. ...
... National initiative launched to support CMS, hospital-acquired,conditions ... Today the National Business,Coalition on Health ... Centers,for Medicare and Medicaid Services, (CMS) efforts ... for specific "Never Events" -- serious and,costly ...
... cases, unproven ,therapies, can be dangerous, experts say , , ... turn to the Internet as a source of information ... are betrayed by purveyors of so-called cancer "cures" that ... five companies were charged with making false and misleading ...
... readers of improper removal of asbestos in St. Louis that may ... The city used an unapproved "wet method" of removing asbestos fibers, ... evaporates. , ... Denver, CO (PRWEB) September 29, 2008 ...
Cached Medicine News:Health News:Suze Orman Joins got milk? Milk Mustache Campaign: New Ad Encourages Families To Invest in Milk's Nutritional Assets 2Health News:Suze Orman Joins got milk? Milk Mustache Campaign: New Ad Encourages Families To Invest in Milk's Nutritional Assets 3Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 2Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 3Health News:Video: 2008 US Olympic Gymnastic Superstars Join Today's Top Music Icons for Women's Cancer Awareness Network Special, Frosted Pink with a Twist 4Health News:Seniors in Poor Areas More Likely to Die After Surgery 2Health News:National Business Coalition on Health Endorses New CMS 'Never Events' Policy 2Health News:National Business Coalition on Health Endorses New CMS 'Never Events' Policy 3Health News:National Business Coalition on Health Endorses New CMS 'Never Events' Policy 4Health News:Scams and Shams That Prey on Cancer Patients 2Health News:Scams and Shams That Prey on Cancer Patients 3Health News:LegalView Reports Cancer Risk for St. Louis Residents After Unapproved Asbestos Removal During Demolition 2Health News:LegalView Reports Cancer Risk for St. Louis Residents After Unapproved Asbestos Removal During Demolition 3
Blunt tipped forceps wlth a small grasping platform on each tip. For grasping fine membranes or grasping membranes adherent to the retinal surface....
Blunt tipped forceps with a smooth, pliable silicone coating on the entire interior surface of the tip. For removal of foreign bodies or atraumatic tissue grasping....
Blunt tipped forceps with small, slightly rounded tips angled perpendicular to the shaft. For grasping peripheral membranes....
Blunt tipped forceps with small, slightly pointed grasping platforms on each tip. For general purpose (fine) membrane grasping and grasping membranes adherent to the retlnal surface....
Medicine Products: