Navigation Links
First Phase II Short-Term Study on Dapagliflozin Shows Results on,Safety, Tolerability and Glycemic Markers in Subjects With Type 2,Diabetes

gs the pharmacokinetic half-life and duration of action. Dapagliflozin is currently in Phase IIb development.

About SGLT2 Inhibitors

Glucose is normally filtered by the kidney, but nearly all of it is reabsorbed in the proximal tubule by SGLT2, which is located almost exclusively in the kidney. For patients with diabetes, retention of excess glucose by this pathway contributes to persistent high blood glucose levels, or hyperglycemia. Inhibiting SGLT2 activity modulates reabsorption of glucose in the kidney, resulting in excretion of glucose in the urine. Research, in animal models, indicates that modulation of renal glucose absorption with SGLT2 inhibition reduces blood glucose independent of insulin secretion or action.

Bristol-Myers Squibb and AstraZeneca Partnership

In January 2007, Bristol-Myers Squibb and AstraZeneca entered into a collaboration to develop and commercialize saxagliptin and dapagliflozin, two compounds under investigation by Bristol-Myers Squibb for the treatment of diabetes. Both companies will jointly set development and commercial strategy for the two compounds. AstraZeneca will provide funding for the majority of currently planned development activities; additional development activity will be funded equally.

About Bristol-Myers Squibb

Bristol-Myers Squibb is a global pharmaceutical and related healthcare products company whose mission is to extend and enhance human life.

Bristol-Myers Squibb Forward-Looking Statement

This press release contains "forward-looking statements" as that term is defined in the Private Securities Litigation Reform Act of 1995, regarding the development and commercialization of products. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual outcomes and results to differ materially from current expectations. No forw
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
3. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
4. Ablynx Announces Interim Results of First Nanobody Phase I Study of ALX-0081 (ANTI-VWF)
5. Advanced Life Sciences Announces Supplemental Efficacy Data from First Pivotal Phase 3 Pneumonia Clinical Trial
6. Advanced Life Sciences to Host Conference Call to Discuss Data From Cethromycins First of Two Phase 3 Pneumonia Trials
7. Advanced Cell Technology Develops First Human Embryonic Stem Cell Line without Destroying an Embryo
8. First Demonstration of nanoImmunology: a Nanomaterials-based Therapeutic Approach to Treat Allergy
9. First single breast cancer study to show significant survival benefit for women switching from tamoxifen to Arimidex
10. Mymetics HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model
11. Dasatinib Shows High Early Response Rate as First Treatment for Chronic Myelogenous Leukemia, M. D. Anderson Researchers Report
Post Your Comments:
(Date:5/17/2013)... Conn. , May 17, 2013  Boehringer ... in respiratory disease at the American Thoracic Society ... PA , May 17 – 22. ... product approved for the treatment of chronic obstructive ... powder)], as well as investigational compounds for asthma, ...
(Date:5/17/2013)...  Sanofi (EURONEXT: SAN and NYSE: SNY ) ... , examining the selective JAK2 inhibitor SAR302503 for ... groups. The primary endpoint assessed the proportion of patients ... reported in previous trials, the most common adverse events ... be presented at an upcoming medical congress. ...
(Date:5/17/2013)... Mass. , May 17, 2013  Boston Scientific ... participate at the annual EuroPCR Scientific Program May 21-24 ... are pleased to present a particularly rich and diversified ... Keith Dawkins , M.D., global chief medical ... trials will be presented, including the NG PROMUS trial, ...
Breaking Medicine Technology:Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 2Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 3Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 4Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 5Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 6Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 7Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 8Sanofi Reports Positive Topline Results from Pivotal Phase III JAKARTA Study for JAK2 Inhibitor in Myelofibrosis 2Sanofi Reports Positive Topline Results from Pivotal Phase III JAKARTA Study for JAK2 Inhibitor in Myelofibrosis 3Sanofi Reports Positive Topline Results from Pivotal Phase III JAKARTA Study for JAK2 Inhibitor in Myelofibrosis 4Sanofi Reports Positive Topline Results from Pivotal Phase III JAKARTA Study for JAK2 Inhibitor in Myelofibrosis 5Sanofi Reports Positive Topline Results from Pivotal Phase III JAKARTA Study for JAK2 Inhibitor in Myelofibrosis 6Boston Scientific Schedule of Major Events and Presentations at EuroPCR 2013 2Boston Scientific Schedule of Major Events and Presentations at EuroPCR 2013 3Boston Scientific Schedule of Major Events and Presentations at EuroPCR 2013 4Boston Scientific Schedule of Major Events and Presentations at EuroPCR 2013 5Boston Scientific Schedule of Major Events and Presentations at EuroPCR 2013 6Boston Scientific Schedule of Major Events and Presentations at EuroPCR 2013 7Boston Scientific Schedule of Major Events and Presentations at EuroPCR 2013 8
... Daylight Saving Time comes to an end on Sunday, Nov. ... Sixty percent of Americans say that they experience a sleep problem ... Foundation,s 2011 Sleep in America poll, and for those individuals the ... season, fall back into bed for not only an extra hour, ...
... Telik, Inc. (Nasdaq: TELK ) announced ... related analogs at the 2011 Meeting of the AACR-NCI-EORTC ... San Francisco, California.  Details of the presentation are as ... disrupt binding of GSTP1 to all three major MAP ...
Cached Medicine Technology:Keep the Time Change From Disrupting Your Rest With Sleep Formula 39™ 2Telik Announces Ezatiostat (Telintra®) Preclinical Presentation at the 2011 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics 2
(Date:5/19/2013)... (PRWEB) May 19, 2013 Fat Burning ... loss program that provides people with fat burning ... people order this Fat Burning Furnace package, people will ... that they can download quickly. The Fat Burning Furnace ... helps people build lean muscle mass. In addition, this ...
(Date:5/19/2013)... Farming methods have changed many times ... 10,000 years ago. Most recently, the Green Revolution has ... genetically engineered seeds and by applying chemical fertilizers and ... these techniques due to the adverse environmental and health ... surge in interest in organic, sustainable farming practices and ...
(Date:5/19/2013)... Vegas, Nevada (PRWEB) May 19, 2013 ... agency , is proud to announce the launch it's ... Awards at the MGM Grand on 5/19/2013. Consumers traveling ... all new special pricing available on VegasHotelEscapes.com's website. Travelers ... that they beat any competitors price. , Vegas Hotel ...
(Date:5/19/2013)... Exciting new Skin Brushes are available from ... practice known through the ages but is a lost ... brushing, has so many benefits for our health and ... love that circulation and lymphatic systems get a boost ... is supported through Skin Brushing." , Why is Skin ...
(Date:5/19/2013)... 2013 Buenos Aires, Argentina: Yoga classes ( ... Buenos Aires, Argentina by the Sivananda Yoga Vedanta ... 2372 - (Barrio Norte). Classes are 90 minutes and ... are offered in a calm environment, allowing visitors to ... healthy vegetarian food, among others. , The Yoga classes ...
Breaking Medicine News(10 mins):Health News:Fat Burning Diet | How “Fat Burning Furnace” Helps People Lose Their Weight Naturally And Fast – V-kool 2Health News:Green Acre Aquaponics Introduces a Revolutionary Approach to Farm Education and Commercial Aquaponics 2Health News:Green Acre Aquaponics Introduces a Revolutionary Approach to Farm Education and Commercial Aquaponics 3Health News:Exciting New Skin Brushes at Sublime Beauty® Bring Health and Beauty Benefits; Celebrities and Models Know the Secret 2Health News:Clases de Yoga in Buenos Aires, Argentina (Yoga Classes) Now Offered by Sivananda Yoga Vedanta Center 2
... AMA Makes ,House Call, to Washington, Discusses New National Physician ... ... The American Medical,Association (AMA) National House Call campaign visits Washington today to,draw ... Medicare patients. Medicare plans to slash physician payments,10 percent on January 1, ...
... N.Y., Sept. 18 Lynn Clark,Callister, R.N., Ph.D., ... has joined the March of Dimes National Nurse ... nursing leaders who,give direction and counsel to March ... Dimes Nurse Advisory Council members represent the finest,maternal-child ...
... Insight Now(TM) automatically imports data from health plans, labs, ... ... health care actions, EATONTOWN, ... provider, has developed an on-line personal health,record with a built-in ...
... Sept. 18 ,The HealthCentral Network, Inc. ( ... today announced a collaboration leveraging,APF,s strength as ... with HealthCentral.com,s multimedia capabilities and extensive,online community ... officially,kicked off today with the posting of ...
... Suite operates with Gryphon compliance services ... in increased productivity for call centers, OKLAHOMA ... of,intelligent customer interaction solutions, today announced that it ... worldwide leader in,On-Demand Contact Governance solutions. This agreement ...
... Demand Entertainment Package for a ... Marks First LodgeNet Deployment in a Children,s Hospital, ... Corporation (Nasdaq: LNET ) and Children,s Hospital,of Pittsburgh ... "kid,friendly" LodgeNetRX Interactive Patient Television System, the company,s,first ever ...
Cached Medicine News:Health News:Medicare Cuts to Physicians Will Harm Washington Seniors 2Health News:Lynn Clark Callister, National Leader in Maternal-Child Health Nursing, Joins March of Dimes Advisory Council 2Health News:Triveris Introduces Personal Health Record with Built-in Health Advisor 2Health News:The American Pain Foundation (APF) and The HealthCentral Network Collaborate to Develop Enhanced Internet Resources for People with Pain 2Health News:The American Pain Foundation (APF) and The HealthCentral Network Collaborate to Develop Enhanced Internet Resources for People with Pain 3Health News:Amcat Partners With Gryphon to Provide Comprehensive and Guaranteed Do Not Call (DNC) Compliance Solution for Outbound Contact Activities 2Health News:Amcat Partners With Gryphon to Provide Comprehensive and Guaranteed Do Not Call (DNC) Compliance Solution for Outbound Contact Activities 3Health News:LodgeNet Deploys Customized 'Kid Friendly' Solution With Children's Hospital of Pittsburgh of UPMC 2Health News:LodgeNet Deploys Customized 'Kid Friendly' Solution With Children's Hospital of Pittsburgh of UPMC 3
Softsplint after bunion surgery. Hook-and-loop closure. Maintains hallux positioning and metatarsophalangeal alignment. Washable....
... deep vein thrombosis, the Aircast VenaFlow System ... compression and rapid impulse inflation. This combination ... ejection while producing more shear stress to ... with tube assembly (cuffs are sold separately). ...
Comfor™ Cast Boot - Rocker Sole - Closed Toe...
The Multi-Purpose Medical-Surgical Shoe...
Medicine Products: