Navigation Links
First Controlled Large-Scale Intervention Angiotensin Receptor,Blocker (ARB) Trial in a Japanese Population, JIKEI HEART Study,Demonstrates Significant Reduction in Blood Pressure and Protection,of Organs with Valsartan

rgans."

In the JIKEI HEART Study, treatment was initiated in a population with an average starting blood pressure of 139/81 mmHg -- already below the national guideline level for hypertension without comorbidities. The blood pressure target was set at 130/80 mmHg. The non-ARB group achieved 132/78 mmHg and the valsartan group achieved 131/77 mmHg. The valsartan group also showed a significant drop in composite cardiovascular events: the primary endpoint cardiovascular events were compared between the groups with the valsartan- added group exhibiting significant relative reductions, including a 65% reduction in angina pectoris, 46% in heart failure and 81% in aortic dissection. These benefits cannot be entirely explained by differences in blood pressure control.

"We are very proud that the University has led yet another landmark, large-scale clinical study. We are equally proud that the important findings of the JIKEI HEART Study were published in the prestigious general medical journal The Lancet, which also marks the 120-year anniversary of our first large-scale trial on beriberi published in the same medical journal," said Satoshi Kurihara, President, Jikei University School of Medicine. "In accordance with our mission of patient-centered medical care, the JIKEI HEART Study provides invaluable clinical insight into current and future treatments for the benefit of patients. We are grateful to the patients for their cooperation, and the physicians who ensured a high level of accuracy with a patient follow-up rate of 99%. The design of the physician-lead study provides a direction for future clinical investigations while attaining a high level of international commendation."

About the large-scale clinical JIKEI HEART Study

The JIKEI HEART Study was a multi-center comparative study with a prospective randomized open-label blinded endpoint (PROBE) design conducted by physicians. The study involved 3,081 Japanese patients aged 20 to 79 with h
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
3. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
4. Ablynx Announces Interim Results of First Nanobody Phase I Study of ALX-0081 (ANTI-VWF)
5. Advanced Life Sciences Announces Supplemental Efficacy Data from First Pivotal Phase 3 Pneumonia Clinical Trial
6. Advanced Life Sciences to Host Conference Call to Discuss Data From Cethromycins First of Two Phase 3 Pneumonia Trials
7. First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes
8. Advanced Cell Technology Develops First Human Embryonic Stem Cell Line without Destroying an Embryo
9. First Demonstration of nanoImmunology: a Nanomaterials-based Therapeutic Approach to Treat Allergy
10. First single breast cancer study to show significant survival benefit for women switching from tamoxifen to Arimidex
11. Mymetics HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model
Post Your Comments:
(Date:9/30/2014)... NEW YORK , Sept. 30, 2014 /PRNewswire/ ... - 2014 Summary Global Markets Direct,s, ... 2014, provides an overview of the Arbor Pharmaceuticals, ... report provides comprehensive information on the current therapeutic ... comparative analysis at various stages, therapeutics assessment by ...
(Date:9/30/2014)... According to the ... Product [Enzymes (Glycosyltransferase, Neuraminidase, Glycosidase), Instruments (HPLC, ... (Immunology, Oncology) & by End User - ... provides a detailed overview of the major ... and strategies impacting the global glycomics enzymes, ...
(Date:9/30/2014)... , Sept. 30, 2014 Valeant Pharmaceuticals International, ... today announced that the company,s Bridgewater, New ... the U.S. Food and Drug Administration (FDA) relating to ... with regards to Sculptra Aesthetic injectable, which was divested ... to the management of Valeant,s contract manufacturers (rather than ...
Breaking Medicine Technology:Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 2Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 3Glycobiology / Glycomics Market Worth $928.11 Million by 2019 2Glycobiology / Glycomics Market Worth $928.11 Million by 2019 3Glycobiology / Glycomics Market Worth $928.11 Million by 2019 4Valeant Pharmaceuticals' Bridgewater Location Receives Warning Letter From FDA 2
(Date:9/30/2014)... and radiotherapy at the same time could stop them ... published in Cancer Research * today (Wednesday). ... Manchester and funded by MedImmune, the global biologics research ... found that combining the two treatments helped the immune ... killed by the initial radiotherapy in mice with breast, ...
(Date:9/30/2014)... News) -- There,s no genetic evidence that high levels ... new study says. Some previous research had suggested ... against type 2 diabetes, raising the possibility of a ... disease. In this study, British researchers investigated the ... on genes that control blood levels of vitamin D. ...
(Date:9/30/2014)... Randy Dotinga HealthDay Reporter ... unemployment rates climb, women tend to put the brakes on ... out to be a permanent choice, new research suggests. ... not to have a child during tough economic times. But, ... women will remain childless into their 40s and beyond. ...
(Date:9/30/2014)... Health Day Reporter TUESDAY, Sept. ... are overweight or obese when diagnosed appear to face ... cancer, new research suggests. , , The finding didn,t ... the potential for developing other cancers associated with obesity. ... reported being overweight or obese prior to diagnosis had ...
(Date:9/30/2014)... [Brown University] Autism is no stranger to the ... African nation is access to clinical services, including reliable ... measure, for example, validated for use in Swahili, a ... study, however, researchers at Brown University and the University ... that they implemented at two sites in the country ...
Breaking Medicine News(10 mins):Health News:Immunotherapy could stop resistance to radiotherapy 2Health News:Gene Study Finds No Proof Vitamin D Guards Against Type 2 Diabetes 2Health News:Recessions May Thwart a Woman's Motherhood Plans Forever: Study 2Health News:Recessions May Thwart a Woman's Motherhood Plans Forever: Study 3Health News:Obesity Tied to Higher Cancer Risk for Colon Cancer Survivors 2Health News:Obesity Tied to Higher Cancer Risk for Colon Cancer Survivors 3Health News:New diagnostic approach for autism in Tanzania 2Health News:New diagnostic approach for autism in Tanzania 3Health News:New diagnostic approach for autism in Tanzania 4
... CHICAGO, Aug. 21 Illinois U.S. Senate candidate Cheryle Jackson ... achieve the dual goals of containing costs and expanding access to ... , Jackson said that health care cooperatives are not ... national public plan that competes with the private insurance industry because ...
... ... Attract, Retain and Serve Health Insurance Consumers , ... Orlando, FL (Vocus) August 21, 2009 -- As the ... is making individual consumers become more involved in the health insurance decision-making process, as ...
... Angeles, London, New Delhi, Singapore and Washington DC (August 21, ... could benefit from a lighter touch but from a ... created a touchy-feely robot that detects tougher tumour tissue in ... human. The technique also minimises tissue damage. Surgeons have ...
... Brown adipose tissue (BAT) brown fat, which is found ... lead to new ways of preventing obesity. Studies have ... obesity. Therefore, promoting BAT function could prevent or reduce obesity ... Symonds, Professor of Developmental Physiology in the School of Clincal ...
... Aug. 21 President Obama,s Council of Advisors on Science and ... reform, energy and the environment -- and the President is listening. ... little about our healthcare system that does not concern us," said ... A primary care physician, he noted that less than 20 ...
... and good rapport with physician is key, , FRIDAY, ... acid reflux is one of the most common complaints ... appear to work best to ease patients, suffering. , ... -- formally called gastroesophageal reflux disease (GERD) -- typically ...
Cached Medicine News:Health News:U.S. Senate Candidate Cheryle Jackson: 'Public Option Critical to Real Health Care Reform' 2Health News:Connextions Cited in Leading Industry Analyst Firm's 'Hype Cycle for Healthcare Payers' 2Health News:Connextions Cited in Leading Industry Analyst Firm's 'Hype Cycle for Healthcare Payers' 3Health News:Connextions Cited in Leading Industry Analyst Firm's 'Hype Cycle for Healthcare Payers' 4Health News:Robot's gentle touch aids delicate cancer surgery 2Health News:Robot's gentle touch aids delicate cancer surgery 3Health News:Daylight could help control our weight 2Health News:PCAST Members Advise President on Future of Healthcare, Energy 2Health News:Right Match of Drug, Doctor Can Boost Reflux Outcomes 2Health News:Right Match of Drug, Doctor Can Boost Reflux Outcomes 3
... Screen Tests are available in 14 configurations ... Designed using Microgenics Antibody Technology, the SureStep™ ... of care immunoassay targeted to detect MDMA ... and MDEA but no cross-reactivity to any ...
... The InstaCheck® multi-drug test device ... and easily. Negative results can ... as 3 minutes; positive results ... simple, one-time urine sample application ...
Accu-Stat Home Drug Test for Marijuana (THC), Cocaine (COC), Amphetamine (AMP), Methamphetamine (mAMP), Opiates (OPI), and Phencyclidine (PCP)....
... onsite test! QuickScreen™ multi-panel dip cards offer ... your choice of any conceivable combination of ... flexibility for your drug testing program. Just ... the built-in timer tells you when to ...
Medicine Products: