Navigation Links
First Controlled Large-Scale Intervention Angiotensin Receptor,Blocker (ARB) Trial in a Japanese Population, JIKEI HEART Study,Demonstrates Significant Reduction in Blood Pressure and Protection,of Organs with Valsartan

Unprecedented Evidence for the Effectiveness of Hypertension Treatment Valsartan in Preventing Cardiovascular Events in Japanese Patients

TOKYO, April 26, 2007 /Xinhua-PRNewswire/ -- The clinical outcomes of the JIKEI HEART Study, the large-scale clinical trial headed by the Jikei University School of Medicine, was today published in the internationally renowned medical journal The Lancet. The study, involving more than 3,000 patients, is one of the largest cardiovascular intervention trials conducted in a Japanese population under realistic clinical settings. It also is the first large- scale study evaluating the benefits of the ARB, valsartan, in Japanese patients.

In the study, valsartan was added to conventional therapy to control blood pressure and protect against cardiovascular events and stroke. The results showed significant benefit with the use of valsartan, including a 39% decrease in cardiovascular events and a 40% decrease in stroke compared to conventional non-ARB therapy. Initiated in 2001, the JIKEI HEART Study was terminated earlier than anticipated at the request of the Data and Safety Monitoring Board due to superior outcomes for the valsartan group over the control group.

"Treatment of hypertension needs to account for blood pressure control but also should take into account the prevention of cardiovascular diseases over an extended period," said Seibu Mochizuki, M.D., PhD, formerly of Jikei University School of Medicine, chief investigator of the JIKEI HEART Study. "In the JIKEI HEART Study we accomplished both -- we achieved the lowest blood pressure value ever set in a morbidity/mortality outcomes trial and saw tremendous benefit for the valsartan arm in reducing the risk of cardiovascular events as well as stroke. Because of this, valsartan will play an important role in treating hypertension as it has been shown to lower blood pressure while being highly protective of end o
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
2. Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkins Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy
3. Genzyme Announces Data from First Phase 3 Study of Tolevamer in Patients with C. difficile Associated Diarrhea
4. Ablynx Announces Interim Results of First Nanobody Phase I Study of ALX-0081 (ANTI-VWF)
5. Advanced Life Sciences Announces Supplemental Efficacy Data from First Pivotal Phase 3 Pneumonia Clinical Trial
6. Advanced Life Sciences to Host Conference Call to Discuss Data From Cethromycins First of Two Phase 3 Pneumonia Trials
7. First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes
8. Advanced Cell Technology Develops First Human Embryonic Stem Cell Line without Destroying an Embryo
9. First Demonstration of nanoImmunology: a Nanomaterials-based Therapeutic Approach to Treat Allergy
10. First single breast cancer study to show significant survival benefit for women switching from tamoxifen to Arimidex
11. Mymetics HIV Vaccine Demonstrates First-Ever Production of Neutralizing IgA Antibodies in Non-Human Primate Model
Post Your Comments:
(Date:8/28/2015)... Korea , Aug. 28, 2015 ... University and Dr. Ra from Biostar , Published ... Confirmed 30% increase of lifespan through multiple IV administration ... physical vitality, and life expectancy found , Commercialization ... Korea have determined the possibility that adult mesenchymal stem ...
(Date:8/27/2015)... 27, 2015  The Academy of Managed Care ... Administration,s (FDA,s) draft guidance and proposed rule that ... to bear a nonproprietary name with an FDA-designated ... a decision from the FDA on the naming ... stakeholders urging the agency to use the same ...
(Date:8/27/2015)... , August 27, 2015 According to a ... Hammock, Toilet, Seating, Universal, Standing, Bariatric ), Material (Nylon, Padded, Canvas), ... to 2020", published by MarketsandMarkets, the Medical Lifting Sling Market is ... Million in 2015, at a CAGR of 11.4 % from 2015 ... ma rket data T ables and ...
Breaking Medicine Technology:Korean Researchers Find the Possibility that Adult Mesenchymal Stem Cells (MSCs) May Extend Lifespan 2AMCP Is Disappointed in FDA's Draft Guidance and Proposed Rule Calling for Suffix on Nonproprietary Names of Biological Products 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 3Medical Lifting Sling Market Worth USD 706.0 Million by 2020 4
... The chairman of the U.S. bishops, Committee on Pro-Life ... (FDA) over its move toward approving a new drug that may ... 17 letter to Dr. Margaret Hamburg , Commissioner of ... Houston criticized the FDA,s move to hold an advisory committee ...
... Amnis Corporation, a manufacturer of advanced cell ... option for the ImageStreamX cell analysis system. The AutoSampler ... a wide variety of 96 well plates, including standard-height ... The acquisition software incorporates easy-to-use templates that allow multiple ...
Cached Medicine Technology:Pro-Life Chair Voices 'Grave Concern' over FDA Plan to Approve Abortion Drug for 'Emergency Contraception' 2Pro-Life Chair Voices 'Grave Concern' over FDA Plan to Approve Abortion Drug for 'Emergency Contraception' 3Pro-Life Chair Voices 'Grave Concern' over FDA Plan to Approve Abortion Drug for 'Emergency Contraception' 4Amnis Releases AutoSampler Option for the ImageStreamX 2
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... ... of the Veterans Award, honoring military veterans leading in business. Mr. Troy ... , The inaugural Nashville Business Journal's 2015 Veterans Awards will recognize ...
(Date:8/28/2015)... ... , ... The Quatela Center for Plastic Surgery is excited to bring patients ... approved by the Food and Drug Administration to eliminate submental fat, also known as ... are among the premier cosmetic surgeons in Rochester to offer this innovative procedure.     ...
(Date:8/28/2015)... ... August 28, 2015 , ... Healthpointe clinics throughout ... go deep sea diving. The act of recreational diving exposes the body ... reasons, it is vital that all recreational and professional divers undergo regular comprehensive ...
(Date:8/28/2015)... ... August 28, 2015 , ... United Benefit Advisors (UBA), ... Insurance Group as its newest Partner Firm. Founded in 1924 and headquartered in ... focused on their goals. Within the past 10 years, TJS Insurance Group has ...
(Date:8/28/2015)... ... 28, 2015 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... to be taken in order to ease the stress on the atmosphere, and ... yet to understand fully the real cause of global warming and urges them to ...
Breaking Medicine News(10 mins):Health News:MyGenetx Board Member Receives Veterans Award 2Health News:Non-surgical Treatment to Get Rid of The "Double Chin," Kybella™, Now Available at the Quatela Center for Plastic Surgery 2Health News:Non-surgical Treatment to Get Rid of The "Double Chin," Kybella™, Now Available at the Quatela Center for Plastic Surgery 3Health News:Healthpointe Now Offering Scuba Physicals 2Health News:TJS Insurance Group Is Latest Partner Firm To Join United Benefit Advisors 2Health News:TJS Insurance Group Is Latest Partner Firm To Join United Benefit Advisors 3Health News:Wake Up and Smell the Sick Atmosphere Says Yisrayl Hawkins in New Article This Week 2
... annual flu vaccines in children ages 16 and younger have ... key measures. ,The finding was especially true for children ... their shots. Children who received a weakened form of the ... children under age 2 who received the inactivated form of ...
... found to increase the incidence of incontinence in postmenopausal ... ,Estrogen plus progestin or estrogen alone has ... therapy (MHT), which consists of estrogen and progestin treatment, ... night sweats, and vaginal dryness. MHT was often prescribed ...
... that had plagued new mothers all over the world, // was ... of this belief, many pregnant women opted for a planned caesarian ... the recent issue of British Medical Journal says that this may ... University, who had led the team of researchers in the study, ...
... WHO had urged the people to be prepared for any outbreak ... spreads from birds to other animal species, even to humans, WHO ... may soon mutate itself to a form that may spread the ... immunity will be unable to handle. ,The disease was first ...
... say those in the early stages of antidepressant medication ... suicidal behavior . ,For the study more than ... studied. Patients taking SSRIs were twice as likely to ... found no difference in patients taking SSRIs and ...
... has devised a test to predict dental caries in children. ... concentration of various sugar chains called oligosaccharides. ,Sugar ... the teeth surface. Some sugar chains repel bacteria to attack ... the tooth. Each individual sugar chain components are determined by ...
Cached Medicine News:
... Cerner PowerChart Electronic Medical Record system ... to create an enterprise-wide, multifacility, multi-entity, ... streamlines the workflow process into one ... the functions that support the electronic ...
Developed in a Microsoft Windows environment, MedInformatix provides physician practices a Computerized Patient Record (CPR) with a Practice Management System (PMS) that is both integrated and design...
... Health Record (EHR/EMR) and ... Specialties that we currently ... Cardiology, Dermatology, Family Medicine, ... Neurosurgery, Obstetrics and Gynecology, ...
... MRAnywhere stands for Medical ... Electronic Medical Records (EMR) software ... charts from within your office, ... Wide Web. MRAnywhere offers conversion ...
Medicine Products: