Navigation Links
Expert Opinion Highlights Avigen's AV411 as Potential New,Therapeutic for Neuropathic Pain and Opioid Withdrawal


Focus On AV411's Unique Mechanism of Action and Broad Potential for the Treatment of Neurological Conditions

ALAMEDA, Calif., June 26, 2007 (PRIME NEWSWIRE) -- Avigen, Inc. (Nasdaq:AVGN), a biopharmaceutical company innovating therapeutics for the treatment of neurological conditions, announced today that Expert Opinion on Investigational Drugs has published an article featuring Avigen's pipeline product, AV411 (ibudilast), a potential first-in-class, non-opioid oral treatment for the management of multiple neurological indications, including neuropathic pain and opioid withdrawal.

"The work on this medication demonstrates the potential of basic neuroscience research, yielding a novel approach to the management of neuropathic pain, enhancement of opiate analgesia, and the management of opiate withdrawal. It's my hope that all these possible avenues will be pursued in addition to further basic research that may uncover other clinical applications of this putative medication," stated Frank Vocci, M.D., Director, Division of Treatment Research and Development, National Institute on Drug Abuse, National Institutes of Health.

According to the National Pain Foundation, neuropathic pain affects up to four million people in the United States. Existing medications, such as opioids, often have modest efficacy in controlling chronic pain because they are targeted specifically to act on neurons. Additionally, opioid use can lead to dependence and withdrawal. Avigen scientists, led by Kirk Johnson, Ph.D., Vice President of Research and Development, in collaboration with researchers at the University of Colorado, Boulder, and the University of Adelaide, Australia, are developing AV411 to address this unmet medical need of controlling chronic pain, while avoiding opioid tolerance and withdrawal.

AV411, in early phase II clinical development in patients with diabetic neuropathic pain, modulat
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Neuroblastoma Expert Reviews Progress and Challenges in Fighting Difficult Pediatric Cancer
2. BusinessWeek Article Highlights Promising Breakthrough Treatment for Advanced Coronary Artery Disease
3. BusinessWeek Article Highlights Promising Breakthrough Treatment for Advanced Coronary Artery Disease
4. Positive Clinical Results for DG041 Lead Product Development Highlights at deCODE R&D Event
5. Ambrilia Highlights Encouraging Data for its HIV Integrase Inhibitor Program and Recent Developments at Annual Meeting
6. July Issue of Journal of Antimicrobial Chemotherapy Highlights Study of Factive Tablets for Five-Day Treatment of Community-Acquired Pneumonia
7. Inovio Biomedical Highlights Enhanced DNA Vaccine Potency with Electroporation DNA Delivery Technology and New Devices at Gene Therapy Meeting
8. Presentations at 2007 European Stroke Congress Highlights New Direction for Viprinex (ancrod)
9. Data to be Presented at ASCO 2007 Highlights sanofi-aventis Commitment to Cancer Care and Research
10. MedImmune Highlights Advances in Inflammatory Disease Pipeline With Series of Data Presentations
11. New Critical Path Report Highlights Research Needed to Foster Generic Drug Development
Post Your Comments:
(Date:10/30/2014)... 2014 Boston Scientific Corporation (NYSE: ... Credit Suisse Annual Healthcare Conference on Tuesday, November 11, ... Dan Brennan , executive vice president and chief financial ... at approximately 8:00 a.m. PT followed by a question ... the presentation and question and answer session will be ...
(Date:10/30/2014)... , Oct. 30, 2014 CVS Health (NYSE: ... new clinical affiliations with three leading regional health systems to ... The collaborating health systems include Baptist Health System in ... which include Commonwealth Health in Pennsylvania , ... Arizona , and Tennova Healthcare in Tennessee ...
(Date:10/30/2014)... --  BioLife Solutions , Inc. (NASDAQ: BLFS ... clinical grade hypothermic storage and cryopreservation ... for cells and tissues, today announced today that ... released on Thursday, November 6, 2014, and that the ... at 1:30 p.m. PST that afternoon. Management will provide ...
Breaking Medicine Technology:Boston Scientific To Participate In 2014 Credit Suisse Annual Healthcare Conference 2CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 2CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 3CVS Health Announces New Clinical Affiliations with Leading Regional Health Systems 4BioLife Solutions to Report Financial Results for Third Quarter 2014 and Provide Business Update on November 6, 2014 2
(Date:10/30/2014)... By Tara Haelle ... (HealthDay News) -- More than 100 genes have been ... new studies report. And researchers say they are ... overall that may contribute to the disorder. Autism ... by communication and social difficulties and repetitive behaviors. An ...
(Date:10/30/2014)... Dr. Joseph Furlin MD, a certified obstetrician ... practices; OB GYN in Melrose Park, IL and ... contains important information about each of the care services and ... forms in English and Spanish. The navigation of the ... the website provide Dr. Furlin’s patients with important information regarding ...
(Date:10/30/2014)... 2014 USARAD Holdings Inc ... and specialty telemedicine solutions provider, including SecondOpinions.com ... existing teleradiology services at Mission Bend ER, it ... telemedicine services, to the state-of-the-art, 24/7, freestanding ER ... of this innovative partnership, there will be many ...
(Date:10/30/2014)... York (PRWEB) October 30, 2014 The ... (NAMS) came to a close on Saturday, October ... since the Society’s inception in 1989. NAMS is North ... and quality of life of all women during midlife ... aging. With over 2,000 physicians and thought leaders from ...
(Date:10/30/2014)... 2014 (HealthDay News) -- When it comes to heart disease, ... to delay care when they have symptoms that spell trouble. ... the hospital with a more severe or advanced stage of ... author Catherine Kreatsoulas, a Fulbright Scholar and research fellow at ... release from the Heart and Stroke Foundation of Canada. ...
Breaking Medicine News(10 mins):Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 2Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 2Health News:USARAD HOLDINGS INC, SECONDOPINIONS.COM® Pioneers Specialty On-Demand Telemedicine And Second Opinion Service At Houston-Based, Mission Bend Freestanding ER Chain 3Health News:Highlights from The North American Menopause Society 25th Annual Meeting 2Health News:Highlights from The North American Menopause Society 25th Annual Meeting 3Health News:Women Often Ignore Signs of Heart Trouble 2
... the West. But a UK expert has warned that they ... for food, usually vegetables or legumes , that have been ... paste or thick liquid. ,The term comes from ... exclusively on breast or formula milk for the first six ...
... for the conflict in Sudan's Darfur region, where droughts ... Ki-moon said in an editorial published Saturday. ... and political shorthand - an ethnic conflict pitting Arab ... The Washington Post. "Look to its roots, though, and ...
... ultrasound early in pregnancy, combined with maternal blood analysis, ... Down Syndrome . ,ng of pregnant women ... analysis, has reduced the number of children born in ... tell the annual conference of the European Society of ...
... stigma is attached to it, especially when it involves children. But ... parents have told them that it was the same with Jonty. ... one of the most famous epileptics in sporting history- Jonty Rhodes. ... prowess, South African cricketer Rhodes who suffered epilepsy as a kid, ...
... based in Oak Brook, Illinois, in cooperation with US officials, ... "Thomas and Friends" wooden train toys made in China ... ,The toys, wooden vehicles, buildings and other train-set ... 2007, pose a danger to young children, who are likely ...
... found that non-invasive screening in early pregnancy reduces ... Brndum-Nielsen, of the Kennedy Institute, Glostrup, Denmark, ... with ultrasound early in pregnancy, combined with maternal ... born in Denmark with Down Syndrome by 50 ...
Cached Medicine News:Health News:Pureed Products Unnecessary and Harmful for Babies UK Expert 2Health News:Climatic Change Cause of Dafur Conflict-UN 2Health News:Early Pregnancy Test Reduces Down Syndrome in Children 2Health News:World Epilepsy Week - 2007 2Health News:World Epilepsy Week - 2007 3Health News:World Epilepsy Week - 2007 4Health News:World Epilepsy Week - 2007 5Health News:World Epilepsy Week - 2007 6Health News:World Epilepsy Week - 2007 7Health News:Lead Scare Causes Thomas to Derail 2Health News:Non-invasive Screening in Early Pregnancy Halves Down's Syndrome Births 2
... 2 adjustable belt buckle. You adjust once and ... off your shoulders. And now theres our Lady ... anatomy. ,For additional back support try one of ... on the vertebrae and help lift the apron ...
The Easy Wrap Apron is now available with an attached Thyroid Collar. The Thyroid Collar is held on with velcro so it adjusts to fully protect the neck. This Apron with Collar is available in 5mm lea...
The major innovation in posterior stabilized (PS) knee design. Improve patellofemoral kinematics. Reduce wear rate potential. Increase resistance to posterior tibial dislocation. Achieve at least 120...
StelKast's Proven™ Knee System is a long term high quality solution based on a clinically proven and successful design....
Medicine Products: