( ngletherapies could be effectively tre...)Exforge Helps Vast Majority of Patients Effectively Control Their,Blood Pressure After Failing on Other Medicines, According to New,Clinical Data,Health

In patients with type 2 diabetes in the same study, Exforge helped an impressive five out of 10 achieve a more aggressive treatment goal of reducing blood pressure to 130/80 mmHg.

"Most patients will require two or more medications to achieve optimal sustained blood pressure control," said Dr. Joseph Izzo, the lead investigator from the Department of Medicine at the State University of New York in Buffalo. "These data show that using Exforge in a real-life setting can get patients who were previously uncontrolled to a healthy blood pressure goal."

Following Swiss and European Union approval in early 2007, Exforge is currently available in Germany, Switzerland and the UK and is planned to be launched in the rest of the EU in 2007/2008. The US Food and Drug Administration (FDA) granted tentative approval for Exforge in December 2006, and this medicine is expected to become available in the US later in 2007 following the expiration of market exclusivity for Norvasc®* (amlodipine).

"Exforge is a very exciting addition to our cardiovascular portfolio," said Dr. James Shannon, Global Head of Development at Novartis Pharma AG. "The fact that nearly 70% of people with high blood pressure still do not have this potentially fatal condition under control demonstrates the need for powerful and more effective therapies."

High blood pressure and its consequences is the world's No. 1 cause of death[5]. This condition, also called hypertension, is when the blood in the body moves through the blood vessels at a higher pressure than normal and causes damage to the arteries, kidneys, brain and ot
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