Navigation Links
Efficacy and Safety Profile of Basilea's Alitretinoin for Severe,Refractory Chronic Hand Eczema Confirmed by Data Shown at European,Dermatology Congress

after single and repeated oral dosing of 5, 10 and 20mg in healthy volunteers. Schmitt-Hoffman A, Roos B, Brown T, Maares J.

P289 / Alitretinoin (BAL4079; 9-cis retinoic acid): Mass-balance excretion study of oral alitretinoin in healthy volunteers. Schmitt-Hoffman A, Roos B, Brown T, van Lier JJ.

P290 / Alitretinoin (BAL4079: 9-cis retinoic acid): Low levels in seminal fluid after repeated oral dosing. Schmitt-Hoffman A, Roos B, Brown T, Meyer I.

About Chronic Hand Eczema (CHE) Hand eczema is a common skin disease and is often chronic and relapsing. It is estimated to affect up to 10% of the general population. The more severe, chronic form of the condition is thought to affect up to 7% of these patients, many of whom do not respond, or no longer respond to topical corticosteroids. Basilea estimates there are at least one million patients in Europe and North America with severe refractory CHE for which currently no approved, effective pharmaceutical treatment is available.

About Alitretinoin Alitretinoin is an investigational drug being developed in Phase III clinical trials by Basilea as a novel treatment for severe refractory Chronic Hand Eczema (CHE), a complex disease for which no effective treatment options are currently available. Alitretinoin has been shown to be effective in clinical studies in patients with severe refractory CHE. Alitretinoin is a teratogen and therefore pregnancy prevention measures must be in place for all women of child-bearing potential who receive alitretinoin. Within days after discontinuation of therapy, alitretinoin levels return to endogenous levels. In clinical studies the post-treatment contraceptive period was four weeks.

About Basilea Basilea Pharmaceutica Ltd. is an independent biopharmaceutical company headquartered in Basel, Switzerland, and listed on the SWX Swiss Exchange (SWX:BSLN). Basilea's fully integrated research and development operations are currently focused on new antibacteria
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
2. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
3. New Phase 3 Study Published in The Lancet Evaluates Efficacy and Safety of Prezista/Ritonavir vs. Kaletra as Part of HIV Combination Therapy in Treatment-Experienced Adults With HIV
4. Advanced Life Sciences Announces Supplemental Efficacy Data from First Pivotal Phase 3 Pneumonia Clinical Trial
5. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
6. New Proof of Genisteins Efficacy and Safety for Osteopenia and Osteoporosis Published in Annals of Internal Medicine
7. Late Breaking Data Released at ADA Showed that the Investigational Use of Januvia and Metformin as Initial Combination Therapy Provided Significant Glucose Lowering Efficacy over 54 Weeks in Patients with Type 2 Diabetes
8. New Research Demonstrates Broad Efficacy of Azixa (MPC-6827) Against Multiple Tumor Types and in Drug Resistant Cell Lines
9. Repros Reports That Proellex Has Demonstrated Superior Efficacy and Safety in Endometriosis When Compared to Standard of Drug Care
10. Medivations Dimebon Maintains Statistically Significant Benefit on All Five Efficacy Endpoints in Alzheimers Disease Trial After One Year of Therapy
11. Studies Show Efficacy and Safety of Alexions Soliris in Broad Population of PNH Patients
Post Your Comments:
(Date:8/3/2015)... , Aug. 3, 2015   ConvergeHEALTH ... company Allergan plc is expanding its ... Intermountain Healthcare to include women,s health.  ... OutcomesMiner analytics platform to generate real-world clinical insights ... "We look forward to expanding our work ...
(Date:8/3/2015)... Va. , Aug. 3, 2015  Dr. ... joining Orthopaedic & Spine Center today, ... to manage their chronic pain through psychological counseling ... is a Fellowship-trained, certified medical psychologist with ... medicine. His vast experience ranges from assessment and ...
(Date:8/3/2015)... 3, 2015  BioElectronics Corporation (OTC Pink: BIEL), maker ... that Andrew J. Whelan , President will be ... "On Business" at 9am EDT on Wednesday, August 5 ... to: http://tunein.com/radio/Money-Matters-Boston-1120-s27548/ ... acceptance the company,s flagship product, ActiPatch Therapy, is achieving ...
Breaking Medicine Technology:ConvergeHEALTH by Deloitte and Intermountain Healthcare Expand Real World Evidence Collaboration with Allergan to Focus on Women's Health 2ConvergeHEALTH by Deloitte and Intermountain Healthcare Expand Real World Evidence Collaboration with Allergan to Focus on Women's Health 3ConvergeHEALTH by Deloitte and Intermountain Healthcare Expand Real World Evidence Collaboration with Allergan to Focus on Women's Health 4Orthopaedic & Spine Center Introduces New Pain Psychologist 2UpTick News Wire Radio Show Will Interview BioElectronics' CEO Andrew Whelan 2
(Date:8/3/2015)... Va. (PRWEB) , ... August 03, 2015 , ... The ... the use of health IT to create efficiencies in healthcare information exchange, announced the ... letters to the Health and Human Services (HHS) Secretary, WEDI shared survey results ...
(Date:8/3/2015)... ... August 03, 2015 , ... Bayer has agreed to pay ... claims in which a claimant alleged to have suffered an arterial blood clot including ... control pills, Yaz, Yasmin and Ocella, has been ongoing for well-over five years. In ...
(Date:8/3/2015)... (PRWEB) , ... August 03, 2015 , ... ... services to contract research organisations (CROs) for a slew of benefits, allowing them ... research and operations, boost quality with cost-effective utilisation of resources, get access to ...
(Date:8/3/2015)... ... August 03, 2015 , ... ... retailer of nutritional supplements, has officially opened the polls for their eleventh ... the following categories:, ,     Brand of the Year (BPI ...
(Date:8/3/2015)... ... ... The art of preparing and cooking food comes naturally to some. For ... Nasreen Zereshki was extremely eager to cook Persian cuisine. Now that she is skilled ... Kitchen with the world. , Since Americans tend to be undereducated about Persian cuisine, ...
Breaking Medicine News(10 mins):Health News:WEDI ICD-10 Survey Results: Industry Nearing Readiness but Physician Practices Lagging Behind 2Health News:WEDI ICD-10 Survey Results: Industry Nearing Readiness but Physician Practices Lagging Behind 3Health News:WEDI ICD-10 Survey Results: Industry Nearing Readiness but Physician Practices Lagging Behind 4Health News:Bayer Agrees To Settle Yaz Aterial Blood Clot Lawsuits 2Health News:Global CRO Market Space Reviewed by Aniruddha Sowale in In-demand Research Report Available at MarketPublishers.com 2Health News:Global CRO Market Space Reviewed by Aniruddha Sowale in In-demand Research Report Available at MarketPublishers.com 3Health News:BPI Sports is Nominated for 11 Different 2015 Bodybuilding.com Supplement Awards 2Health News:BPI Sports is Nominated for 11 Different 2015 Bodybuilding.com Supplement Awards 3Health News:Persian Cuisine: Colorful and Extremely Healthy 2
... (HealthDay News) -- Drug users who inject themselves with ... than those abusing other drugs, new research reveals. ... in a mixture of social, structural and neurobiological factors, ... Health in New York City and the University of ...
... Dennis Thompson HealthDay Reporter , FRIDAY, Dec. 30 ... diabetes when she was 19 years old and a student ... in Montgomery Village, Md., Keys had been suffering the classic ... "That prompted me to just go to the doctor," she ...
... 29 (HealthDay News) -- There are many ways to prevent ... easiest ways is also one of the most important: proper ... when people travel and get together for parties and other ... Safety noted. "Hand-washing is the single most effective way ...
... Women recently diagnosed with breast cancer have higher survival ... the American Cancer Society. However, survivors continue to face ... as many as 50 percent of breast cancer survivors ... Sinclair School of Nursing say a meditation technique can ...
... , THURSDAY, Dec. 29 (HealthDay News) -- In some cases, ... "silent strokes," new research suggests. Such strokes, which may ... dead brain cells, and are found in roughly 25 percent ... aspect of this study of memory loss in the elderly ...
... HealthDay Reporter , THURSDAY, Dec. 29 (HealthDay News) -- If ... blood tests, an imaging test like an MRI or ultrasound, ... really necessary?" you might have wondered. That,s a question ... of evidence suggests that overuse of diagnostic testing may be ...
Cached Medicine News:Health News:Meth Users Much More Likely to Try Suicide 2Health News:A Life-Saving Lesson That Took Decades to Learn 2Health News:Hand-Washing Key to Stopping Spread of Disease 2Health News:Breast cancer survivors benefit from practicing Mindfulness-based Stress Reduction 2Health News:'Silent Strokes' Linked to Memory Loss in Elderly: Study 2Health News:Is American Medicine Too Test Happy? 2Health News:Is American Medicine Too Test Happy? 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: