Navigation Links
Diabetes Linked to Higher Parkinson's Risk

Studies Also Show Eating Soy Nuts May Reduce Inflammation After Menopause; Weight-Loss Surgery Improves Beta Cell Function, Reduces Insulin Resistance

ALEXANDRIA, Va., March 28, 2007 /PRNewswire/ -- People who have type 2 diabetes are more likely to develop Parkinson's disease as they age, though researchers are uncertain what accounts for the link between the two diseases, according to a new study being published in the April issue of Diabetes Care.

The study, by researchers in Finland, is the first large prospective study to find type 2 diabetes to be a risk factor for Parkinson's disease, a movement disorder characterized by muscle rigidity and tremors.

According to the authors, people with type 2 diabetes are 83 percent more likely to be diagnosed with Parkinson's than people in the general population. The study found the association between the two diseases existed for both men and women, independently of other confounding factors.

"Diabetes might increase the risk of Parkinson's disease partly through excess body weight," the researchers hypothesized, since their work showed that excess body weight was also associated with an elevated risk of Parkinson's disease. However, they concluded that more research needed to be done to fully understand the mechanisms behind this link.

Soy Nut Consumption Reduces Markers of Inflammation

Eating soy nuts instead of red meat decreases some markers of inflammation and improves endothelial function in postmenopausal women with a collection of cardiometabolic risk factors, a new study by researchers at Isfahan University of Medical Sciences in Iran and the Harvard School of Public Health found. In previous studies by the same group, subjects who ate soy nuts also showed improvements in their lipid profiles, suggesting that soy may improve cardiac health among a subgroup of women.

Previous research has looked at the effect of soy o n inflammatory markers and endothelial function in the general population, but this was the first study to look more narrowly at how eating soy nuts (versus soy protein) would specifically affect postmenopausal women who already had a number of metabolic abnormalities. Consuming soy protein did not produce the same benefits, the researchers found.

Women (and men) who have certain cardiometabolic risk factors (abdominal obesity, high blood pressure, high cholesterol and insulin resistance) are at high risk for type 2 diabetes and for heart disease, the number one killer of people with diabetes. Studies have shown that lifestyle changes, such as losing moderate amounts of weight and increasing physical activity, can substantially reduce the chances of developing diabetes for people who already have these risk factors.

"A well-balanced meal plan should be part of any program designed to lose weight or improve overall health. This study shows that adding soy nuts to your diet -- and eating less red meat -- could be an important part of that meal plan," said lead researcher Dr. Leila Azadbakht, at the Isfahan University of Medical Sciences Department of Nutrition in Iran.

Soy is also often used as an alternative or adjunct to hormone replacement therapy in postmenopausal women. The researchers note that the mechanisms by which soy affects the inflammatory state may be related to the effects of soy phytoestrogens, which mimic hormone replacement therapy. However, more research needs to be done to understand the mechanisms through which soy affects inflammation and endothelial function. It is also unclear whether other groups of postmenopausal women would benefit as much as those participating in this study who had a number of high risk factors for diabetes and heart disease.

Weight-Loss Surgery Reduces Insulin Resistance, Improves Beta Cell Function

Bariatric surgery -- any of several procedures designed to reduce how much a person eats or how many calories their bodies absorb -- can reduce insulin resistance and improve beta cell function in severely obese people, regardless of whether they lose any weight, according to a study by researchers in Italy.

With the number of obese people rising rapidly in the U.S. and around the world, bariatric surgery has been growing in popularity. Previous research has shown this surgery can restore glucose tolerance in the majority of severely obese people. But this study found it could also improve beta cell function, regardless of how much weight a person does or doesn't lose after surgery.

Obesity greatly increases a person's risk of developing type 2 diabetes, which is characterized by insulin resistance and impaired beta cell function.

"Why these surgeries would improve beta cell function and glucose tolerance, independent of weight loss, remains unclear," said lead researcher Dr. Ele Ferrannini, Department of Internal Medicine and CNR Institute of Clinical Physiology, University of Pisa School of Medicine, Italy. "But obviously the fact that it does improve beta-cell function could make bariatric surgery a useful tool in the prevention of diabetes in the severely obese patient."

Note: ADA clinical practice guidelines recommend that bariatric surgery may be considered for some individuals with type 2 diabetes who also have a BMI of 35 or higher. While this can result in marked improvements in glycemia, the long-term benefits and risks of bariatric surgery in individuals with pre-diabetes and diabetes continue to be studied.

Diabetes Care, published by the American Diabetes Association, is the leading peer-reviewed journal of clinical research into the nation's fifth leading cause of death by disease. Diabetes also is a leading cause of heart disease and stroke, as well as the leading cause of adult blindness, kidney failure, and non-traumatic amputations. For more information about diabetes, visit the American Diabetes Asso ciation Web site http://www.diabetes.org or call 1-800-DIABETES (1-800-342-2383).

Contact: Rachel Morgan, ADA

(703) 549-1500 ext. 2290

CONTACT: Rachel Morgan of the ADA, +1-703-549-1500, ext. 2290

Web site: http://www.diabetes.org/

Terms and conditions of use apply
Copyright © 2007 PR Newswire Association LLC. All rights reserved.
A United Business Media Company


'"/>




Related medicine technology :

1. Diagnosing Diabetes: Immediate HbA1c Results Improve Glycemic Control
2. A 4-Week Therapy with Transition Therapeutics E1-I.N.T. Leads to Sustained Reductions in Blood Glucose Levels for 6 Months Post-treatment in Type 2 Diabetes Patients
3. Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic Control in Subjects with Type 2 Diabetes Compared to Metformin Alone
4. Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic Control in Subjects with Type 2 Diabetes Compared to Metformin Alone
5. An Investigational Study Released at ADA Showed that Initial Combination Therapy with Januvia (sitagliptin) and Metformin Led to Improvement in Markers of Beta Cell Function in Patients with Type 2 Diabetes
6. SemBioSys Presents Positive Insulin Data at the American Diabetes Association Conference
7. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
8. First Phase II Short-Term Study on Dapagliflozin Shows Results on Safety, Tolerability and Glycemic Markers in Subjects With Type 2 Diabetes
9. Lipitor Reduced the Risk of Coronary Events by Half and Stroke by Nearly One-Third in High-Risk Patients with Type 2 Diabetes Who Experienced a Recent Stroke
10. Sangamo BioSciences Announces Presentation of Phase 1 ZFP Therapeutic Data at American Diabetes Association Meeting
11. Phase IIIb Clinical Data Validate the Overall and Cardiovascular Safety Profile of Cycloset (A Quick Release Formulation of Bromocriptine Mesylate) in Patients with Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... Research and Markets has announced the ... 2016 - Forecast to 2022" report to their offering. ... up to date financial data derived from varied research sources ... with potential impact on the market during the next five ... comprises of sub markets, regional and country level analysis. The ...
(Date:6/23/2016)... INDIANAPOLIS , June 23, 2016 ... Tomorrow,s Leaders Scholarship is any indication, the future is ... online at www.diabetesscholars.org by the Diabetes Scholars ... in the way of academic and community service excellence. ... program since 2012, and continues to advocate for people ...
(Date:6/23/2016)... 23, 2016 Research and Markets ... Volumes: Global Analysis (United States, China, Japan, Brazil, United ... to their offering. ... healthcare business planners, provides surgical procedure volume data in ... with an in-depth analysis of growth drivers and inhibitors, ...
Breaking Medicine Technology:
(Date:6/26/2016)... ... ... a legally blind and certified personal trainer is helping to develop a weight loss fitness ... to fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs ... College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. ... treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. ...
(Date:6/25/2016)... ... , ... First Choice Emergency Room , the largest network of independent ... Director of its new Mesquite-Samuell Farm facility. , “We are pleased to announce ... Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
(Date:6/24/2016)... ... , ... Those who have experienced traumatic events may suffer from a complex ... as drug or alcohol abuse, as a coping mechanism. To avoid this pain and ... a traumatic event. , Trauma sufferers tend to feel a range of emotions, from ...
Breaking Medicine News(10 mins):