Navigation Links
Daytrana (methylphenidate transdermal system) Provides Significant,Effectiveness in ADHD Symptom Relief in Both Boys and Girls

o help manage the potential for late-day side effects.

Significant Symptom Control for Boys and Girls

In this double-blind, 7-week, parallel-group study, investigators randomized 270 children to receive DAYTRANA, OROS methylphenidate or placebo. The 96 children (ITT population) in the DAYTRANA group reported a significant mean reduction of 56.5 percent in their ADHD Rating Scale-IV (ADHD-RS-IV) total scores (-24.24±14.55 points, P<.0001 vs. placebo) from the study start to end, the study's primary endpoint.

The 58 boys that received DAYTRANA averaged a significant 56 percent ADHD- RS-IV total score reduction (-24.28±15.66 points, P<.0001), while the 38 girls averaged a significant 57.4 percent reduction (-24.18±12.88 points, P<.0001).

ADHD-RS-IV assesses 18 individual symptoms of ADHD as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR(R)), a publication of the American Psychiatric Association.

Investigators monitored adverse events throughout the study and for 30 days after the last dose. Adverse events typically were mild to moderate in severity and were consistent with known effects of methylphenidate. No serious adverse events were reported.

The most common treatment-emergent adverse events (>10 percent) in both boys and girls in the trial were decreased appetite, headache, insomnia, nausea and vomiting. Boys in the DAYTRANA group had a higher incidence of vomiting (9 boys vs. 1 girl), tic (7 vs. 0), upper abdominal pain (6 vs. 1), irritability (7 vs. 0) and affect lability (6 vs. 0).

The study was supported by funding from Shire.

About ADHD

Approximately 7.8 percent of all school-age children, or about 4.4 million U.S. children aged 4 to 17 years, have been diagnosed with ADHD at some point in their lives, according to the CDC. ADHD is one of the most common psychiatric disorders in children and a
'"/>




Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. 12-Month Study Demonstrated Tolerability and Efficacy of DAYTRANA (methylphenidate transdermal system)
2. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
3. XTL Provides Update on Phase I Clinical Trial of XTL-2125
4. Cervarix, the GSK Cervical Cancer Candidate Vaccine, Provides Sustained Immune Response in 100 Percent of Women up to 55 Years of Age
5. DURECT Provides an Update to the Memryte Program Under Development by Voyager Pharmaceutical Corp
6. NicOx Provides an Update on the Phase 2a Study for NCX 1000 Conducted With Axcan
7. Indivumed Study Provides Sound Scientific Basis for a Predictive Drug Test- Platform
8. Rigel Provides Clinical Update of R788 Phase 2 Trials in ITP, Rheumatoid Arthritis and Lymphoma
9. New Analysis of Data from WHI Provides Reassurance With Respect to Coronary Heart Disease For Newly Menopausal Women Considering Hormone Therapy
10. Cell Genesys Provides Final Median Survival Data From Second Phase 2 Trial of GVAX Immunotherapy for Prostate Cancer
11. Novavax Vaccine Provides Robust Immune Response, Pre-Clinical Data Show
Post Your Comments:
(Date:7/31/2015)... 2015  In today,s ever-changing marketplace, call centers must ... increasingly connected, and increasingly impatient with slow service. The ... channels and tools is driving call centers to explore ... According to research by benchmarking firm, Best Practices, ... in a call center study realize the impact of ...
(Date:7/31/2015)... , July 31, 2015 The ... press release on July 28, 2015, "Surviving Your ... Launches Fundraising for Patient Safety." A ... sentence should read: "PPAHS is a ... Patients on Opioids. For more information on the National ...
(Date:7/31/2015)... WAYNE, Pa. , July 31, 2015 /PRNewswire/ ... a fully integrated specialty pharmaceutical company focused on ... announced the closing of its previously announced underwritten ... stock at a public offering price of $11.25 ... the offering included 1,000,000 shares issued upon the ...
Breaking Medicine Technology:Best Practices in Building World-Class Consumer & Over-the-Counter Call Centers 2Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 2Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 3Egalet Announces Closing of Public Offering of Common Stock and Exercise in Full of Underwriters' Option to Purchase Additional Shares 4
... VIENNA, Va., June 20, 2007 /PRNewswire/ ... announced the successful completion of,pharmacokinetic and ... hormone, long-acting interferon beta and,long-acting erythropoietin. ... demonstrated superb durability of the long-acting,proteins, ...
... /PRNewswire-FirstCall/ -- Amylin,Pharmaceuticals, Inc. today announced that ... injection and,SYMLIN(R) (pramlintide acetate) injection, and its ... Diabetes Association's,(ADA) 67th Annual Scientific Sessions being ... 26. The company will also host an ...
Cached Medicine Technology:Modigene Announces Successful Completion of Pharmacokinetic &,Pharmacodynamic Pre-Clinical Experiments for Proprietary,Long-Acting Human Growth Hormone, Long-acting Interferon Beta and,Long-acting Erythropoietin 2Modigene Announces Successful Completion of Pharmacokinetic &,Pharmacodynamic Pre-Clinical Experiments for Proprietary,Long-Acting Human Growth Hormone, Long-acting Interferon Beta and,Long-acting Erythropoietin 3Modigene Announces Successful Completion of Pharmacokinetic &,Pharmacodynamic Pre-Clinical Experiments for Proprietary,Long-Acting Human Growth Hormone, Long-acting Interferon Beta and,Long-acting Erythropoietin 4Amylin Pharmaceuticals to Present New Data from Broad Diabetes and,Obesity Programs at ADA 2007 2Amylin Pharmaceuticals to Present New Data from Broad Diabetes and,Obesity Programs at ADA 2007 3Amylin Pharmaceuticals to Present New Data from Broad Diabetes and,Obesity Programs at ADA 2007 4
(Date:8/1/2015)... ... 01, 2015 , ... Calvary Hospital today announced that it is embarking on ... goal is to bring this Torah – dating from 1880 – back to kosher ... services. , Scroll No. 515, from the town of Taus-Domazlice, is on permanent ...
(Date:8/1/2015)... ... 2015 , ... On Tuesday, July 28th, Symantec released a security industry ... behind the attack on Anthem Inc. which resulted in one of the largest data ... and spear phishing campaigns. , For Joe Caruso, founder and CEO/CTO of ...
(Date:8/1/2015)... (PRWEB) , ... August 01, 2015 , ... On March 19, 2015 Phil Valentine – ... trek of the Appalachian Trail by stepping off Springer Mountain and heading north. ... On July 26th Phil reached Connecticut and was greeted by friends and family. He ...
(Date:7/31/2015)... (PRWEB) , ... August 01, 2015 , ... The Honor ... Global Advisory Panel on the Future of Nursing (GAPFON) 20-21 July 2015 in San ... to participate in this meeting. , Dr. Silvia Cassiani, Advisor, Nursing and Allied Health ...
(Date:7/31/2015)... ... July 31, 2015 , ... Recently touted by Becker’s Healthcare ... health analytics , Jvion continues to disrupt the predictive analytic and big data ... patient and population level illness to drive prevention and better health outcomes. Most ...
Breaking Medicine News(10 mins):Health News:Calvary Hospital Announces Plans to Restore Historic Torah 2Health News:Calvary Hospital Announces Plans to Restore Historic Torah 3Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 2Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 3Health News:Frenemy at the Gates - Hackers Excel at Leveraging Trust 4Health News:Connecticut Executive Hikes Appalachian Trail to Raise Awareness About Recovery. 2Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 2Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 3Health News:Key Latin American Nurse Leaders Identify Regional Issues During Global Advisory Panel on the Future of Nursing Meeting 4Health News:Jvion Showcased as Leader in the Predictive Analytic Market 2
... Oct. 31Like normal tissue, tumors thrive on nutrients carried ... of new blood vessels is a hallmark of cancer, ... can keep tumors from growing, too. To better understand ... would like to make detailed maps of the complete ...
... to popular belief, most college students don,t gain anywhere near ... nationwide study. Rather than adding "the freshman 15," as ... 2.5 and 3.5 pounds during the first year of college. ... gain, the study revealed. The typical freshman only gains about ...
... An international collaboration of scientists, including researchers at ... Skin Diseases (NIAMS), a part of the National ... that causes a rare childhood disease characterized predominantly ... that the disorder, named chronic atypical neutrophilic dermatosis ...
... hypertension (PAH) is a rare form of pulmonary hypertension (PH) that ... people out of one million people worldwide per year - most ... 40. While the numbers may not seem significant, the disease ... the causes of PAH remain unknown. As the ...
... , MONDAY, Oct. 31 (HealthDay News) -- Construction workers ... injuries and an increased risk of work-related illness and death, ... national sources and found that a construction worker has a ... 45-year career, and a 1-in-200 risk of being fatally injured ...
... by the Institute for Health Metrics and Evaluation (IHME) ... improved methods for analyzing verbal autopsies a method ... a complete vital registration system are fast, effective, ... to understand disease trends., While many high-income countries such ...
Cached Medicine News:Health News:The 'freshman 15' is just a myth, nationwide study reveals 2Health News:The 'freshman 15' is just a myth, nationwide study reveals 3Health News:NIH scientists discover link among spectrum of childhood diseases 2Health News:LA BioMed's Dr. Ronald Oudiz impacting lives of those with pulmonary hypertension 2Health News:'Hard Hats' Still Have High Rates of Injury, Illness: Report 2Health News:IHME develops fast, affordable ways for countries to better identify causes of death in populations 2Health News:IHME develops fast, affordable ways for countries to better identify causes of death in populations 3Health News:IHME develops fast, affordable ways for countries to better identify causes of death in populations 4
... the only four-color, automated benchtop flow cytometry ... cell sorting. Designed specifically to support a ... offers software instrument control, auto-sample loading, and ... productivity. FACSCalibur is fully modular so it ...
... cytometer especially suited for cell analysis ... CyFlow allows to analyze scatter signals ... fluorescence channels. Data acquisition, analysis, and ... built-in PC employing Partec DPAC software, ...
This unique system combines the analytical power of a research cytometer into a compact, truly walk away, clinical analyzer ergonomically designed to expedite sample throughput....
The Cytomics FC 500 Series delivers flexible testing, powerful software and a user-friendly interface features that help researchers optimize their overall workflow efficiency while maintaining true ...
Medicine Products: