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Data to be Presented at ASCO 2007 Highlights sanofi-aventis,Commitment to Cancer Care and Research

Survival update and prognostic factor analysis of oxaliplatin (ox) and irinotecan (iri) combinations in patients with metastatic colorectal cancer (MCRC).

    -- An updated analysis of the phase III N9741 study evaluating FOLFOX4

       versus irinotecan-based chemotherapy in metastatic colorectal cancer

       patients will be presented.

    -- Monday, June 4, 8:00 AM - 12:00 PM, S Hall A2, Poster Presentation.

Abstract # LBA5 - Final results of the EORTC Intergroup randomized phase III study 40983: Peri-operative FOLFOX4 chemotherapy and surgery for resectable liver metastases from colorectal cancer.

    -- The study examines the use of chemotherapy with oxaliplatin/5FU/LV

       (FOLFOX4) given before and after surgery of liver metastases from

       metastatic colorectal cancer versus surgery alone.  Eloxatin(R) for

       peri-operative use is not in the U.S. label.

    -- Monday, June 4, 3:30 PM - 3:45 PM, N Hall B1, Plenary Session.

For information about currently approved uses of Eloxatin(R), please see full prescribing information.

Taxotere(R) (docetaxel) Injection Concentrate clinical studies:

Abstract # LBA1008 - BCIRG007: First overall survival analysis of a randomized phase III trial of trastuzumab plus docetaxel with or without carboplatin as first line therapy in HER2 amplified metastatic breast cancer (MBC).

    -- This study evaluates the use of two Taxotere(R) - Herceptin

       (trastuzumab) regimens for the treatment of metastatic HER2 positive

       breast cancer patients.

    -- Sunday, June 3, 9:45 AM - 10:00 AM, N Hall B1, Oral Presentation.

Abstract #537 - Estrogen receptor expression and efficacy of docetaxel in early breast cancer: A pooled analysis of 3490 patients included in two randomized trials.

    -- This presentation reviews the use of Taxotere(R) in trials involving

       patients with early stage node positive breast cancer, accor
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