( New data on Eloxatin(R) Taxotere(R) an...)Data to be Presented at ASCO 2007 Highlights sanofi-aventis,Commitment to Cancer Care and Research,Health

BRIDGEWATER, N.J., May 29, 2007 /PRNewswire-FirstCall/ -- Sanofi-aventis announced today that a total of 375 abstracts indicative of its oncology commitment have been accepted for the 43rd Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago, Illinois (June 1-5, 2007). The results from key studies involving the company's leading anticancer agents, Eloxatin(R) (oxaliplatin injection) and Taxotere(R) (docetaxel injection concentrate), will be presented alongside clinical trial data examining investigational agents, aflibercept (VEGF Trap), S-1 (oral fluoropyrimidine) and TroVax(R) (Therapeutic Cancer Vaccine).

Of the abstracts which have been accepted, 129 focus on Eloxatin(R), 214 on Taxotere(R), 29 on S-1, two on VEGF Trap and one on TroVax(R). One hundred and ninety three Eloxatin(R) and Taxotere(R) abstracts were also accepted for presentation at the scientific sessions, with five Eloxatin(R) and 15 Taxotere(R) abstracts to be oral communications, including one Eloxatin(R) presentation at the ASCO plenary session.

The key results presented with Eloxatin(R)-based treatment (in combination with 5FU/LV) cover clinical trials in the adjuvant (post-surgery) colon cancer (MOSAIC study) and the metastatic (advanced) colorectal cancer (NCCTG/N9741study, EORTC40983/EPOC study) settings.

Data looking at Taxotere(R)-based regimens in adjuvant and in metastatic breast cancer will be presented during the meeting.

Two phase II studies examined aflibercept (VEGF Trap) as a single agent in recurrent ovarian and lung cancers. VEGF Trap is an anti-angiogenic agent that blocks the Vascular Endothelial Growth Factor (VEGF), and is currently being investigated to assess its use in stopping tumor growth. Aflibercept is in phase
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