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Data on Telavancin and Micafungin Hold Promise of New Therapeutic,Options in Fight Against Serious Infectious Disease

for serious hospital acquired infections represent a significant challenge in healthcare. Astellas look forward to supporting healthcare professionals in their fight against these often fatal infections".

Notes for Editors:

Micafungin and telavancin registration

Micafungin is currently undergoing clinical evaluation with the EMEA. It is anticipated that registration dossiers for telavancin will be submitted to the registration authorities in Q2 2007.

About Astellas

Astellas is a pharmaceutical company dedicated to improving the health of people around the world through the provision of innovative and reliable pharmaceutical products. The organisation is committed to becoming a global category leader by combining outstanding R&D and marketing capabilities and continuing to grow in the world pharmaceutical market.

Astellas co-operation

In November 2005, Astellas entered into a collaboration arrangement with Theravance for the development and commercialisation of telavancin worldwide except Japan. In July 2006, Astellas and Theravance expanded the collaboration to include Japan. Under the terms of the collaboration, Theravance will lead the development of telavancin for the treatment of cSSSI and hospital-acquired pneumonia, and will collaborate substantially with Astellas in marketing in the United States for the first three years. Astellas will lead all other development, regulatory, manufacturing, sales and marketing activities.

About Theravance

Theravance is a biopharmaceutical company with a pipeline of internally discovered product candidates. Theravance is focused on the discovery, development and commercialisation of small molecule medicines across a number of therapeutic areas including respiratory disease, bacterial infections and gastrointestinal motility dysfunction. Of the five programs in development, two are in late stage - the telavancin program focusing on treating serious Gram-positive
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