Navigation Links
Data from Investigator-Sponsored Trial of Oncophage Cancer Vaccine,in Glioma Presented at American Association of Neurological,Surgeons Annual Meeting

prosan 20 with carmustine implant, MGI Pharma), the first approved local therapy for glioma.

Derived from each individual's tumor, Oncophage contains the 'antigenic fingerprint' of the patient's particular cancer and is designed to reprogram the body's immune system to target only cancer cells bearing this fingerprint. Oncophage is intended to leave healthy tissue unaffected and limit the debilitating side effects typically associated with traditional cancer treatments such as chemotherapy and radiation therapy. Oncophage has been granted fast track and orphan drug designations from the US Food and Drug Administration (FDA) in both metastatic melanoma and renal cell carcinoma.

Study Findings

The investigator-sponsored Phase 1/2 study is designed to evaluate the feasibility, safety and activity of Oncophage vaccination in patients with recurrent, high-grade glioma. The trial involves two cohorts of six patients, both receiving a minimum of four Oncophage injections: the first cohort receives biweekly vaccinations; the second cohort receives weekly vaccinations. Patients are monitored for immune response before and after Oncophage treatment using three different techniques.

According to investigators, no adverse events or toxicity identified were considered attributable to the vaccine. A tumor-specific immune response was detected after vaccination in all 12 patients. The investigators will continue to follow patients for overall survival. Researchers plan to present further results from the Phase 1/2 trial of Oncophage in late 2007 and submit the findings for peer-review publication. Based on these results, the Phase 2 portion of this study is expected to move forward in mid-2007.

"Our goal is to change the management of recurrent glioma from a life threatening disease, in which survival rates are typically 25 to 26 weeks, into a chronic disease with extended survival and improved quality of life for patients," said Dr. Parsa. "Alth
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
2. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
3. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
4. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
5. Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting Systems Success in Mouse Model Reported in Cancer Cell
6. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
7. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
8. Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery
9. TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment
10. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
11. MediGene Announces Cancer-Fighting Virus Shows Promise in Early Clinical Trial
Post Your Comments:
(Date:3/27/2015)... 2015 /CNW Telbec/ - Russell Williams , President ... (Rx&D), welcomes the 2015-2016 Quebec Budget, noting the fiscal ... the biopharmaceutical industry. However, the association is concerned about ... commend the government,s intent to strive for a balanced ... promote Quebec,s economic development is ...
(Date:3/27/2015)... Biopharmaceutical Industry Leads Manufacturing Sector in ... on top as the country,s manufacturing leader in innovation ... ndp│analytics. According to the  analysis , the industry had ... last decade, accounting for 27 percent of average annual ... Short Video on Medicare Part D - Medicare ...
(Date:3/27/2015)... , March 27, 2015 The Temple Health ... April to a 5,000-square-foot building at 1802 South First St. ... area designated by the City of Temple ... & White and the Central Texas Veterans Health Care System, ... laboratory space to early stage biotechnology and life science companies. ...
Breaking Medicine Technology:Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 2Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 3Week in Review: The Latest from PhRMA 2Temple Health & Bioscience District Relocates, Offers Office And Lab Space To Biotech Companies 2
... teleconference to release report with ITPC. Kim says,foundations laid ... had to,build comprehensive health systems in the poorest settings.", ... ,The International Treatment Preparedness Coalition (ITPC), a group of ... its fifth,report on scale up of AIDS services: Missing ...
... BUFFALO, N.Y., Nov. 27 Kinex Pharmaceuticals LLC,announced ... Phase 1 human,testing. The study is entitled "A ... 1 study to evaluate safety, tolerability,and pharmacokinetics of ... to conventional therapies". The drug belongs to an ...
Cached Medicine Technology:New Analysis from 14 Countries Identifies Drug Access Priorities to Achieve 2010 AIDS Treatment Target 2New Analysis from 14 Countries Identifies Drug Access Priorities to Achieve 2010 AIDS Treatment Target 3New Analysis from 14 Countries Identifies Drug Access Priorities to Achieve 2010 AIDS Treatment Target 4First Patient Dosed with KX2-391 in Phase 1 Clinical Trial 2
(Date:3/27/2015)... St. Paul, MN (PRWEB) March 27, 2015 ... first annual Minnesotans for Healthy Kids Coalition Lobby ... and the Statewide Health Improvement Program (SHIP). ... for the 2015 PE Bill SF343/HF498 which would ... benchmarks, require annual student assessments and other measures ...
(Date:3/27/2015)... Since September 2014, the country singer has been ... having been in retirement for a period of 13 years. ... return to touring, and concert events have been booking quickly ... sell out for the two shows recently scheduled for May ... the inventory of discounted Garth Brooks tickets for sale. , ...
(Date:3/27/2015)... Canadian Cannabis Clinics ( http://www.cannabisclinics.ca ... utilization of medical cannabis as a treatment for ... and clinics dedicated to providing access to safe ... for patients searching for medical marijuana treatment in ... their sub domain for Canada. , With ...
(Date:3/27/2015)... April 2015 is the 150th anniversary of the end of ... war and the amazing President that led our country through ... Civil War and Abraham Lincoln. This moving event will be ... Pickens Theater in Newport, RI. , Chief Justice (Ret.) ... master of ceremonies. Dr. Fred Zilian, educator, writer and actor, ...
(Date:3/27/2015)... Pastor and Overseer at The House of Yahweh in Abilene, ... through the Laws of Peace written in the Holy Scriptures ... titled, “Yahweh’s Way-The Great Difference” focuses on the past and ... original biblical instructions has caused mass chaos worldwide. ... the world is based on man-made laws that will never ...
Breaking Medicine News(10 mins):Health News:Everlast Climbing Advocates to Strengthen Physical Education in Minnesota Schools 2Health News:Garth Brooks Tickets for Omaha: BuyCheapTicketsToEvents.com Draws Customers by Discounting Prices on 2015 Tickets for Garth Brooks’ Tour Stops at CenturyLink Center 2Health News:Canadian Cannabis Clinics (CCC) to Join the Canada.MarijuanaDoctors.com Network 2Health News:Relive the Civil War, the Presidency and Shocking Assassination of Abraham Lincoln through Lincoln’s Own Words and the Music of a 46-Piece Orchestra 2Health News:Relive the Civil War, the Presidency and Shocking Assassination of Abraham Lincoln through Lincoln’s Own Words and the Music of a 46-Piece Orchestra 3Health News:Relive the Civil War, the Presidency and Shocking Assassination of Abraham Lincoln through Lincoln’s Own Words and the Music of a 46-Piece Orchestra 4Health News:The World Does Not Have to Continue in Misery, Says Yisrayl Hawkins in New Article 2
... study conducted and headed by Veronique Roger, M.D., M.P.H., at ... is a high risk of these patients suffering from stroke//. ... was 44 times more during the 30 day period after ... person. ,The study is very important because with today’s ...
... Reports from the National Academy of Sciences had shown that ... responsible for the increase in obesity of children’s. Various organizations// ... advertisement food industry is also responsible for the increase in ... to have a check on the marketing of Junk food ...
... University of Birmingham tested the 'Bambach Saddle Seat' invented by ... to relieve backache//. ,The chair, which is priced at ... natural 'S' shape and positions the pelvis correctly. ... made their pelvis tilt backwards slightly and given a task ...
... for persistent pain may be increased by an inflamed injury, ... pain even after it has disappeared//. Several million Canadians are ... Neuroscience has published the study. The NR2B proteins in mice ... serve to imprint upon the brain a painful response even ...
... ,The disabled, homeless man who died on East ... temperatures had refused the help of paramedics, say officials. ... paramedics on Saturday night did actually respond to the ... the patient clearly refused any assistance from the paramedics, ...
... revealed that the country has progressed very little where national ... The disaster response systems are still in a poor condition ... in the US measured up to five or less of ... Carolina and Delaware met 8 indicators. The issues are ...
Cached Medicine News:Health News:New Chair Invented To Relieve Backache 2Health News:US is unprepared for a bio-terrorist attack 2
... developer of laser diagnostics for ophthalmic applications, ... Tomograph 3 (HRT3), a newly-enhanced version of ... and management of glaucoma. ,Like its predecessor, ... a topographical image of a patients optic ...
The NIAGARA Thermal Retention System (TRS) maintains the temperature of prewarmed irrigation fluid continuously as it is delivered through the Corson®, Surgiflex® WAVE™, or Surgiflex D...
... Fr Sur-Catch NT stone retrieval basket raises proven ... Its unique paired wire design and multi-sizing basket ... needs of each patient and procedure. Its ... use with the DURTM-8 Elite Ureteroscope and its ...
The Surgiflex WAVE XP couples the state-of-the-art Surgiflex WAVE Probe with the convenience of a truly portable battery-powered pump....
Medicine Products: