( za-like illness (ILI) (Vesikari T et....)Data Show FluMist May Reduce Seasonal Influenza Burden Among,,,Children in School, Daycare Settings,Health

za-like illness (ILI) (Vesikari, T, et.al., Pediatrics, 2006). New data presented at the PAS meeting estimate the economic impact of these clinical outcomes and find a potential societal cost savings associated with immunizing children against influenza. In the first year of the study, vaccination provided savings of approximately $5.47 per child, while in the second year of the study, the projected savings increased to almost $144 per child. The economic analysis also indicated that the significantly higher savings projected in the second year of the study were due in part to the substantially higher rate of influenza infection among the study population.

"From the societal perspective, influenza immunization of young children at daycare or school settings seems to make economic sense. By reducing influenza attack rates, there is less burden on the healthcare system and fewer days missed from school and work, which drive the societal cost savings," said Parthiv Mahadevia, M.D., MPH, senior director of health outcomes and pharmacoeconomics.

Reduction of Disease Burden and Increased Savings in School-based Vaccination Program

Data from a community-based study involving 15,000 children in 28 schools across four states (Maryland, Texas, Minnesota and Washington) showed that households of the 11 schools where children received FluMist reported statistically significant reductions in ILI, child doctors' office visits, medications and work/school absenteeism in the peak flu week as compared to the households of the 17 control schools where no influenza vaccinations were provided. The study, conducted by researchers at the University of Maryland Medical Center, was designed to determine the impact of school-based vaccination on children and households. All school households were asked to complete a survey on ILI symptoms, healthcare use (such as spending on over- the-counter medicines and
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