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Data Show FluMist May Reduce Seasonal Influenza Burden Among,,,Children in School, Daycare Settings

New Economic Analyses of School and Daycare Study Outcomes Suggest Vaccinating Against Influenza May Produce Cost Savings for Community at Large

TORONTO, May 08, 2007 /PRNewswire-FirstCall/ -- MedImmune, Inc. announced today research results showing that use of FluMist(R) (Influenza Virus Vaccine Live, Intranasal) in daycare and school settings may help reduce the burden of seasonal influenza. Economic analyses applied to outcomes observed in previously completed clinical studies suggest that influenza vaccination may provide a beneficial cost savings to the community at large. The results were presented at the annual meeting of the Pediatric Academic Societies (PAS) taking place this week in Toronto, Canada. Additional data were presented from a study showing that increased vaccination rates may help prevent late-season influenza B outbreaks, as well as from a post-licensure safety analysis of FluMist that showed that the vaccine was well-tolerated.

"The results of the various FluMist-associated clinical and pharmacoeconomic studies presented at the PAS meeting are encouraging both individually and collectively," said Robert Walker, M.D., vice president, clinical development. "These data show us that innovative influenza vaccination approaches may have benefits that extend beyond just protection of the vaccinated individual. Immunizing children at places where they gather such as schools and daycare is logical, since children are often the main source of the spread of influenza in a community."

Cost-Effectiveness of Preventing Influenza in Young Children Attending Daycare Centers

Results from a previously completed and published placebo-controlled, two- season trial involving children aged 6 months to 36 months attending daycare centers showed that those children receiving FluMist experienced significantly fewer cases of influen
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