Navigation Links
Data Available From Erbitux Phase III Study in First-Line Treatment,of Advanced Lung Cancer

se (ILD), which was fatal in one case, occurred in less than 0.5% of 774 patients with advanced colorectal cancer (mCRC) receiving ERBITUX. There was one case of ILD reported in 796 patients with head and neck cancer receiving ERBITUX in clinical studies.

In clinical studies of ERBITUX, dermatologic toxicities, including acneform rash, skin drying and fissuring, inflammatory and infectious sequelae (eg, blepharitis, cheilitis, cellulitis, cyst), and hypertrichosis were reported. In 208 patients receiving ERBITUX + RT, acneform rash was reported in 87% (17% severe) as compared to 10% in 212 patients treated with radiation therapy alone (1% severe). In patients receiving ERBITUX alone, 76% (N=103) experienced acneform rash (1% severe). In patients with mCRC, acneform rash was reported in 89% (686/774) of all treated patients, and was severe in 11% (84/774). Subsequent to the development of severe dermatologic toxicities, complications including S. aureus sepsis and abscesses requiring incision and drainage were reported. Sun exposure may exacerbate these effects. A related nail disorder, occurring in 12% (0.4% Grade 3) of patients, was characterized as a paronychial inflammation.

The safety of ERBITUX in combination with radiation therapy and cisplatin has not been established. Death and serious cardiotoxicity were observed in a single-am trial with ERBITUX, delayed, accelerated (concomitant boost) fractionation radiation therapy, and cisplatin (100 mg/m2) conducted in patients with locally advanced squamous cell carcinoma of the head and neck. Two of 21 patients died, one as a result of pneumonia and one of an unknown cause. Four patients discontinued treatment due to adverse events. Two of these discontinuations were due to cardiac events (myocardial infarction in one patient and arrhythmia, diminished cardiac output, and hypotension in the other patient).

The incidence of hypomagnesemia (both overall and severe [NCI CTC Grades 3 & 4]) was i
'"/>




Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Positive Results Prompt US National Cancer Institute to Make Glivec Available to Patients in Post-Surgical GIST Study
2. Positive Results Prompt US National Cancer Institute to Make Gleevec Available To Patients in Post-Surgical Gist Study
3. Data Available from Erbitux Phase III Study in First-Line Treatment of Advanced Pancreatic Cancer
4. Survival Data Available From Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer
5. Survival Data Available from Erbitux Study in First-Line Treatment of Advanced Head and Neck Cancer
6. Extensive Clinical Data on Erbitux Presented at the 2007 ASCO Annual Meeting
7. Merck at ASCO 2007: Spectrum of Studies Reinforces Promise of Erbitux for Colorectal and Head and Neck Cancer Patients
8. Randomized Phase III Trial Showed Erbitux Significantly Improved Secondary Endpoints of Progression-Free Survival and Disease Control in Metastatic Colorectal Cancer Patients
9. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
10. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
11. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
Post Your Comments:
(Date:1/23/2015)... DUBLIN , Jan. 23, 2015 Research and Markets ... "Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, ... offering. Video communication has been the topic of ... the United States and the Soviet Russia. ...
(Date:1/23/2015)... , Jan. 23, 2015  A new analysis of ... D 2015 enrollment data shows that 81 percent of ... access and extra discounts at certain pharmacies. The findings ... "Preferred pharmacy plans are now the foundation of Medicare ...
(Date:1/23/2015)... , Jan. 23, 2015  Immune Therapeutics, Inc. today announced ... for the compounding, packaging and distributing of its naltrexone tablets. ... the United States . KRS Global ... naltrexone tablets in various strengths for individual patients in response ...
Breaking Medicine Technology:Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Video Telemedicine Market- Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4
... and NEW YORK, Aug. 30 Inc. ... on its fourth annual Inc. 5000 list, an exclusive ... represents the most comprehensive look at the most important ... website Pandora, convenience store chain 7-Eleven, Brooklyn Brewery, and ...
... Fla., Aug. 30 Bioheart, Inc. - ... of the Cell Therapy Foundation is to improve public ... research and education. The Foundation aims to promote basic ... of this mission Cell Therapy Foundation provides updates concerning ...
Cached Medicine Technology:West Physics Consulting Lands on the 2010 Inc. 5000 List 2West Physics Consulting Lands on the 2010 Inc. 5000 List 3Bioheart's MyoCell Recognized as one of the Breakthrough Developments of 2010 2Bioheart's MyoCell Recognized as one of the Breakthrough Developments of 2010 3Bioheart's MyoCell Recognized as one of the Breakthrough Developments of 2010 4
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has recently ... View website of AngelWeddingDress.com to find more details. ... online for a bridal party. AngelWeddingDress offers a variety ... Its maternity wedding dresses are specially designed for 2015. ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Thousand of ... Medical Care recalled its GranuFlo and NaturaLyte dialysis concentrates ... underway in U.S. District Court, District of Massachusetts, Bernstein ... 20th, the Court has remanded a case filed by ...
(Date:1/22/2015)... Joan Lunden, award-winning American journalist, beloved television host, ... 32nd Annual Miami Breast Cancer Conference planned and ... , shares that “a fast-growing, virulent” cancer in her ... not followed up her clean mammogram with an ultrasound. ...
(Date:1/22/2015)... 2015 IsoComforter, Inc. has introduced the most ... IsoTube design to treat specific body parts and muscle groups. ... and easy to use patented cold therapy machine with the ... orthopedic and muscle injuries. IsoComforter has become the industry ...
(Date:1/22/2015)... As interest in the value of spiritual ... worldwide, Rev. Eric J. Hall , president and CEO ... will be the keynote speaker on January 27 at an ... system. , The conference, “Hope and Resilience: Innovative and Interdisciplinary ...
Breaking Medicine News(10 mins):Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:IsoComforter Introduces Best of Class Cold Therapy Product to the Worldwide Market 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3
... the urgent need to change practices contributing to global ... marketplace. ,"Climate change is not a northern problem," ... Programme (UNEP). "It touches on every sector." ... Business Summit for the Environment, the first major international ...
... With summer setting in, Shimla is running short of water ... ,While the hill station with a 250,000 population needs eight ... for distribution, according to the Shimla Municipal Corporation. ... on alternate days to meet this shortage. ,According ...
... A prototype of a robotic device, resembling a caterpillar has ... precision heart operations without the use of anesthetics. // ... in Pittsburgh, Pennsylvania released a report in the journal New ... contracted, and ‘crawls’ at about 18cm per minute, across ...
... Welfare, Smt. Panabaka Lakshmi Inaugurated the Orientation and Capacity ... Boards on “Strategies for Conservation and Cultivation of Medicinal ... said that our strategies and action plans should focus ... bio-diversity in the forest areas but promote cultivation of ...
... repellents don’t prevent bites and therefore don’t prevent disease ... should not be manufactured, advertised or used for mosquito ... so,” said lead author A. Ali Enayati, Ph.D., lecturer ... Sciences in Sari, Iran. ,The review appears ...
... from the University of Nottingham are exploring the medical condition ... Pain. ,David Humes of the Division of Gastroenterology, ... motive to understand pain, has begun to delve into pain ... ,Dr David Humes said: "Our aim is to ...
Cached Medicine News:Health News:Asian Business Executives Urged to Be Eco-friendly 2Health News:HeartLander - Futuristic Medical Technology Takes Off 2Health News:Exports Of Herbal & Dietary Products Has Huge Potential 2Health News:Electronic Mosquito Repellents Fail to Prevent Malaria Transmission 2
... The 8180 Series customized digital ... all your endoscopy video needs. ... and customized menus to best ... 8180 Series cameras are interchangeable ...
... provides easy-to-use features, auto iris, white balance, ... head construction is based on Solos durable ... Camera System, International (GS 9960-PAL) includes: , ... video cables , (GS 9965) Camera head ...
... 1-Chip Camera System provides easy-to-use features, auto ... scope. The camera head construction is based ... 12, Complete 1-Chip Camera System, International (GS9900-PAL) ... (CCU) with power cord and video cables ...
... The 3-Chip Camera System offers 800+ lines ... auto iris, automatic gain control, and white ... ,Complete 3-Chip Camera System for Microscopic ... (MS 1000-01) Camera Control Unit (CCU) with ...
Medicine Products: