Navigation Links
Dade Behrings (hsCRP) Tests and BNTM Series Analyzers


C-Reactive Protein (CRP) is an inflammatory marker that has been associated with an increased risk of having a cardiovascular eventeven in the face of normal LDL levelsin several studies. CRP is created by the liver during systemic infection, and is an acute inflammatory marker. While CRP testing has been around for many years, it has only been recently that tests sensitive enough to measure the mildly elevated levels that occur with CHD have been developed.

Dade Behring is the developer and manufacturer of high-sensitivity CRP (hsCRP) tests that can be used as a diagnostic aid for the physician for determining cardiac risk factors. This method was first approved by the FDA for marketing in the U.S. in November of 1999.

Dade Behrings CRP test can be run using either whole blood or plasma and requires nephlometric systems (such as the BNTM series produced by Dade Behring) for running analyses. The test is based on nephelometric analysis of latex particles coated with CRP monoclonal antibodies, which is much more sensitive than prior manual ELISA testing for CRP levels.

Current AHA and CDC guidelines indicate that while this test should not be used as routine screening for the general public, it can be used for screening for patients at intermediate risk (10 to 20 percent chance of having a cardiac or cerebral vascular event within the next 10 years). Using this test as an adjunct to normal lipid profiles can help identify patients at risk for CHD, MI, and peripheral vascular disease.

The high-sensitive CRP (hsCRP) is available as a variety of reagent tests from the manufacturer. These tests can detect CRP levels as low as ~0.175 mg/L (standard CRP assays cannot detect CRP levels <3.0).

The test should be conducted twice within a two-week period. The CRP looks at the inflammation level and produces a relative risk assessment, states Gary Samuel, a spokesperson for Quest Diagnostics, who provides Dade Behrings test as its Ca rdio CRP. He adds, It predicts the risk of a cardiovascular event relative to the general population, and provides this data in an easy-to-read format.

Test requirements:

Dade Behringers hsCRP test requires 1 mL of blood or plasma serum (minimum of 0.5 mL) at room temperature when it is run. The sample can be refrigerated (for up to one week) or frozen (up to three months) during storage. It is recommended that a fasting sample be collected for best results and that the patient have any inflammatory diseases resolved for at least two weeks prior to testing.

The tests sensitivity is 0.2 mg/L.

The test is standardized against the International Chemistry and Laboratory Medicine (IFCC)/Bureau Communautaire de Rfrence (BCR)/College of American Pathologists (CAP) CRP reference preparation.

Values

Less than 1.0 mg/L is considered low. Levels of 1.0 to 3.0 are average, and 3.1 to 10.0 is considered high. When levels are consistently greater than 10.0, the physician will want to assess for other sources of inflammation.

Reimbursement

Currently, reimbursement by insurance companies varies. Neil Protter, a marketing manager at Dade Behringer states, There is currently a reimbursement code set up under Medicare, but its best to check with individual providers about coverage because not all providers cover testing.
'"/>




Related medicine technology :

1. Point of Care Strep Tests Speed Treatment, Lower Costs
2. Rapid Flu Tests May Prove Especially Helpful This Season
3. Avian (Bird) Flu: Is There a Role for Rapid Tests?
4. Non-Invasive Diagnostic Tests for Celiac Disease
5. Analyzers Offer Point-of-Care Lipid Panels
6. Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
7. Hematology Analyzers Simple, Sophisticated Technology Serving All Patients
8. Urinalysis Analyzers: Large Capabilities in Every Size Device

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... A Small Business Innovative Research (SBIR) grant ... (NIH) to Phoenix -based NeuroEM Therapeutics, ... grant will seek to determine an optimal set of ... waves to treat Alzheimer,s Disease. The grant will also ... treat other neurologic disorders such as Parkinson,s Disease and ...
(Date:12/8/2016)... -- Economic growth in the United States will continue in ... in their December 2016 Semiannual Economic Forecast. Expectations are ... in mid-2009, as indicated in the monthly ISM ® ... manufacturing sector is optimistic about growth in 2017, with ... the non-manufacturing sector indicates that 14 of its industries ...
(Date:12/8/2016)... LOS ANGELES , Dec. 8, 2016 /PRNewswire/ ... and manufacturing of dissolution testing and diffusion testing ... has been acquired by Teledyne Instruments, Inc. ("Teledyne"). ... Hanson,s long-proven line of precision testing instruments, as ... while accelerating development of new products and services. ...
Breaking Medicine Technology:
(Date:12/8/2016)... ... December 08, 2016 , ... CURE Media Group, the nation’s leading ... has aligned with Upstage Lung Cancer in efforts to combat lung cancer, announced CURE ... Hennessy, Jr said, “CURE Media Group is honored to team up with Upstage Lung ...
(Date:12/8/2016)... , ... December 08, 2016 ... ... Suite 10.2 version gives development continuity to its innovative Unified Instance Manager ... management capacity. In addition, this new version optimizes the unattended auto-dialing system ...
(Date:12/8/2016)... ... December 08, 2016 , ... Today’s patients are encouraged to ... mind, SIGVARIS has created a new line of anti-embolism stockings to help prevent ... the benefits of graduated compression when transitioning from recovery to early rehabilitation. , ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... from offices headquartered in Jefferson County, is announcing the launch of a charity ... , The number of homeless women and children in Birmingham has grown steadily ...
(Date:12/8/2016)... ... December 08, 2016 , ... Bill Mull Agencies, a Wichita-based ... and around central Kansas, is joining the Youth Horizons organization for a charity ... Headquartered in Wichita, Youth Horizons works to empower area children from unstable, troubled, ...
Breaking Medicine News(10 mins):