Navigation Links
Dade Behrings (hsCRP) Tests and BNTM Series Analyzers


C-Reactive Protein (CRP) is an inflammatory marker that has been associated with an increased risk of having a cardiovascular eventeven in the face of normal LDL levelsin several studies. CRP is created by the liver during systemic infection, and is an acute inflammatory marker. While CRP testing has been around for many years, it has only been recently that tests sensitive enough to measure the mildly elevated levels that occur with CHD have been developed.

Dade Behring is the developer and manufacturer of high-sensitivity CRP (hsCRP) tests that can be used as a diagnostic aid for the physician for determining cardiac risk factors. This method was first approved by the FDA for marketing in the U.S. in November of 1999.

Dade Behrings CRP test can be run using either whole blood or plasma and requires nephlometric systems (such as the BNTM series produced by Dade Behring) for running analyses. The test is based on nephelometric analysis of latex particles coated with CRP monoclonal antibodies, which is much more sensitive than prior manual ELISA testing for CRP levels.

Current AHA and CDC guidelines indicate that while this test should not be used as routine screening for the general public, it can be used for screening for patients at intermediate risk (10 to 20 percent chance of having a cardiac or cerebral vascular event within the next 10 years). Using this test as an adjunct to normal lipid profiles can help identify patients at risk for CHD, MI, and peripheral vascular disease.

The high-sensitive CRP (hsCRP) is available as a variety of reagent tests from the manufacturer. These tests can detect CRP levels as low as ~0.175 mg/L (standard CRP assays cannot detect CRP levels <3.0).

The test should be conducted twice within a two-week period. The CRP looks at the inflammation level and produces a relative risk assessment, states Gary Samuel, a spokesperson for Quest Diagnostics, who provides Dade Behrings test as its Ca rdio CRP. He adds, It predicts the risk of a cardiovascular event relative to the general population, and provides this data in an easy-to-read format.

Test requirements:

Dade Behringers hsCRP test requires 1 mL of blood or plasma serum (minimum of 0.5 mL) at room temperature when it is run. The sample can be refrigerated (for up to one week) or frozen (up to three months) during storage. It is recommended that a fasting sample be collected for best results and that the patient have any inflammatory diseases resolved for at least two weeks prior to testing.

The tests sensitivity is 0.2 mg/L.

The test is standardized against the International Chemistry and Laboratory Medicine (IFCC)/Bureau Communautaire de Rfrence (BCR)/College of American Pathologists (CAP) CRP reference preparation.

Values

Less than 1.0 mg/L is considered low. Levels of 1.0 to 3.0 are average, and 3.1 to 10.0 is considered high. When levels are consistently greater than 10.0, the physician will want to assess for other sources of inflammation.

Reimbursement

Currently, reimbursement by insurance companies varies. Neil Protter, a marketing manager at Dade Behringer states, There is currently a reimbursement code set up under Medicare, but its best to check with individual providers about coverage because not all providers cover testing.
'"/>




Related medicine technology :

1. Point of Care Strep Tests Speed Treatment, Lower Costs
2. Rapid Flu Tests May Prove Especially Helpful This Season
3. Avian (Bird) Flu: Is There a Role for Rapid Tests?
4. Non-Invasive Diagnostic Tests for Celiac Disease
5. Analyzers Offer Point-of-Care Lipid Panels
6. Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
7. Hematology Analyzers Simple, Sophisticated Technology Serving All Patients
8. Urinalysis Analyzers: Large Capabilities in Every Size Device

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/17/2017)... , January 17, 2017 ... to potentially earn millions in revenue with the planned ... massive numbers of strokes with a simple test that ... Companies with latest developments in the markets today include: ... (NYSE: AZN ), Cancer Genetics, Inc. (NASDAQ: ...
(Date:1/17/2017)... 17, 2017 Catherine ... http://www.touchneurology.com/articles/tailored-temperature-management-neurocritical-care ...      (Logo: ... European Neurological Review , ... Amey reports that despite standard care, temperatures ...
(Date:1/17/2017)... 17, 2017  The pioneer in no-touch UV disinfection has ... Tru-D SmartUVC , short for "total room ultraviolet disinfection," was ... Terminal Room-Disinfection (BETR-D) study which was recently published in ... that Tru-D can cut transmission of four major superbugs by ... to market in 2007, we have been committed to innovation ...
Breaking Medicine Technology:
(Date:1/16/2017)... ... January 16, 2017 , ... Etymotic Research, ... GunSport•PRO® and EB15•LE® electronic earplugs at the NSSF SHOT Show on January 17-20, ... The SHOT Show is the shooting, hunting and outdoor trade show and conference ...
(Date:1/16/2017)... ... 16, 2017 , ... As New York’s fastest growing ophthalmic ... to their medical staff, according to eye surgeon, Jeffrey Martin, MD, FACS, Chief ... division of SightMD. Dr. Giamos will practice primarily out of SightMD’s Riverhead, Southampton, ...
(Date:1/16/2017)... ... ... are well-aware of the following facts at present:, Flu and ... no effect on keeping this particularly bad strain of the flu away , ... sniffling , These facts are well-known among the team at Woodard! About ...
(Date:1/16/2017)... (PRWEB) , ... January 16, 2017 , ... One thing ... only to treat, but to test for, as well. The money spent screening for ... year.(1) Doctors in the U.S. screen patients for cancer more than in any other ...
(Date:1/15/2017)... ... , ... In this role, Courtney will be responsible for developing new business ... friendly mark. This certification program was created by ASL and the nonprofit Asthma and ... suitable for the 60+ million people living in the U.S. with asthma and allergies. ...
Breaking Medicine News(10 mins):