a collected to date, and the pending
completion of the EDEMA4 confirmatory trial already underway, we
believe we will be well positioned to apply for regulatory approval
to bring to market this much needed therapy for the HAE patient
community. The results, which will be presented next week in more
detail, highlight the potential of DX-88 to be a safe and
efficacious therapy. Ultimately, we believe DX-88 will greatly
improve the quality of life of HAE patients worldwide."
EDEMA3 Trial
EDEMA3, the 72-patient, placebo-controlled, multi-center, Phase
3 trial, was conducted at 34 sites in the United States, Europe,
Canada, and Israel. The primary objective of EDEMA3 was to
determine the efficacy and safety of the fixed 30 mg subcutaneous
(SC) dose of DX-88 for patients suffering from moderate to severe
acute HAE attacks. The trial had two phases: a double-blind,
placebo-controlled phase and a repeat dosing phase. In the first
phase, HAE patients received either a single 30 mg SC dose of DX-88
or placebo. After patients received one treatment in the
placebo-controlled portion of the study, they were eligible for the
second, open-label phase of the study, where they receive repeat
dosing with SC DX-88 for any subsequent attacks.
Webcast Presentation Details
Dyax Corp. will host a webcast presentation on Tuesday, April
17, 2007, which will include a discussion of the EDEMA3 results and
the patient reported outcome methodology in more detail. Henry E.
Blair, Chairman and CEO of Dyax, will be joined by senior
management and clinical trial investigators from the EDEMA3
trial.
Date: Tuesday, April 17, 2007
Time: 12:30 p.m. ET
Online Access: Go to the Investor Relations section of the Dyax
website (www.dyax.com) and follow instructions for accessing the
live webcast. Participants may register in advance.
Telephone Access: Domestic callers, dial 1-888-396-2384
International callers, dial 617-847-8711
Passcode
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