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DOR BioPharma Announces Issuance of European Patent for Its Oral,Multivalent Botulinum Toxin Vaccine BT-VACC

MIAMI, FL -- (MARKET WIRE) -- July 06, 2007 -- DOR BioPharma, Inc. (OTCBB: http://studio.financialcontent.com/Engine?Account=iwire&PageName=QUOTE&Ticker=DORB">DORB) ("DOR" or the "Company") announced today that the European Patent Office has granted a patent, EP 1024827 B1, with claims related to oral vaccination using mutated non-toxic forms of botulinum neurotoxin as a vaccine to prevent exposure to botulinum toxin. The European patent follows the issuance of a patent in the United States, U.S. 6,051,239, which was granted in April, 2000 and contains equivalent claims for oral vaccination. DOR has exclusively licensed these issued patents and related patent applications from Thomas Jefferson University.

Both the newly issued European patent and the formerly issued United States patent stem from the work of Dr. Lance Simpson at Thomas Jefferson University demonstrating that mutated forms of botulinum toxin can be administered orally to induce protective immunity to natural toxin exposure. The claims in the granted European patent provide protection for the use of certain non-toxic mutants of botulinum toxin that are capable of translocation from the gut to the general circulation for preparation of an oral vaccine.

"The grant of the European patent describing the underlying technology is an additional milestone that reinforces our patent portfolio in botulinum vaccines," said Christopher J. Schaber, PhD, President and CEO of DOR. "We also have applications in both the US and other key jurisdictions that cover additional features of BT-VACC™. We believe that oral vaccination will provide advantages over injectable botulinum vaccines because of ease of administration and rapid distribution which can facilitate mass inoculations in time of need. We hope to
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