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Cytogen Reports Publication Validating the Utility of its,Proprietary ProChart Database

usefulness of the ProChart data to help them define the WWOX pathway and its role in tumor suppression.

While Cytogen's internal research and development initiatives focus on clinical-stage opportunities, the Company complements its internal programs with an active business development strategy, which includes capitalizing on the promising proprietary technology platforms, such as ProChart, previously developed through its AxCell BioSciences research-stage subsidiary.

In view of recent biological validation, as well as the progress of internal data mining efforts and external research collaborations, Cytogen is exploring strategic transactions for AxCell BioSciences and will be presenting today at the 9th Annual C21 BioVentures Conference (C21) taking place in Monterey, California.

About ProChart(TM)

ProChart is a proprietary, comprehensive, experimentally validated database of protein-protein signaling interactions mediated by WW, SH3, PDZ, and other modular domain families. Cytogen believes the application of ProChart may accelerate research and drug development by: (i) discovering novel signal transduction pathways and their relevant protein-protein interactions; (ii) rapidly identifying qualified drug targets; (iii) identifying potential unwanted side effects; (iv) identifying structure and activity relationship (SAR) information regarding domain and ligand interactions that can facilitate small molecule drug design; and (v) providing high throughput screening reagents (eg, cloned domains and ligands).

About Cytogen

Cytogen is a specialty pharmaceutical company dedicated to advancing the treatment and care of patients by building, developing, and commercializing a portfolio of oncology products. The Company's specialized sales force currently markets three therapeutic products and one diagnostic product to the U.S. oncology market. CAPHOSOL(R) is an advanced electrolyte solution for the treatment of oral mucositis and d
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