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CuraGen and TopoTarget Announce New Clinical Results With,Belinostat to be Reported at Upcoming Major Medical Meetings

BRANFORD, Conn., April 19, 2007 /PRNewswire-FirstCall/ -- CuraGen Corporation and TopoTarget A/S announced today that preliminary interim clinical data on intravenous belinostat (PXD101), a histone deacetylase (HDAC) inhibitor being investigated for the treatment of cancer, are expected to be presented at two upcoming major medical meetings.

One oral and one poster presentation discussing interim clinical results with belinostat will be made at the 2007 American Society of Clinical Oncology (ASCO) Annual Meeting, which is being hosted in Chicago, IL, June 2-5, 2007. A poster presentation will also be made at the 2007 Pan Pacific Lymphoma Conference, which is being hosted on the Island of Maui, Hawaii, June 11-15, 2007.

    2007 ASCO Annual Meeting


    -- An oral presentation entitled, "A Phase Ib/II study of PXD101 alone and

       in combination with 5-fluorouracil in patients with advanced solid

       tumors," will be made during the conference's Clinical Science

       Symposium entitled Breaking the Silence of the Genome: HDAC Inhibitors

       on Saturday, June 2nd from 2:45 - 4:15 p.m.


    -- A poster presentation entitled, "A Phase I/II study of the safety and

       anti-cancer activity of IV-administered belinostat (PXD101) plus

       carboplatin (C) or paclitaxel (P), or both in patients with advanced

       solid tumors," will be made during the conference's Developmental

       Therapeutics: Molecular Therapeutics poster session on Sunday, June

       3rd\from 8:00 a.m. - 12:00 p.m.


    2007 Pan Pacific Lymphoma Conference


    -- A poster presentation entitled, "A Phase II Study of Belinostat

       (PXD101) in Patients with Recurrent or Refractory Cutaneous or

       Peripheral T-Cell Lymphoma," will be on display during the conference

       beginning at 7:00 a.m., Monday, June 11th through Friday, June 15th.

Reprints of the poster presentations wi
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