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CuraGen Presents Update on Clinical Development Program for,Belinostat

706-758-4315 (international) Passcode: 2474675 Webcast: Access to the live webcast and presentation are available at http://www.curagen.com

A replay of the conference call will be available starting at 11:30 a.m. Eastern time on Tuesday, June 12, 2007 through Sunday, August 12, 2007 by dialing 800-642-1687 (domestic) or 706-645-9291 (international). The passcode for the replay is 2474675. An archive of the webcast will also be accessible at http://www.curagen.com.

Reprints of the poster presentations are available on CuraGen's website at www.curagen.com , or by emailing . info@curagen.com

About Belinostat

Belinostat is a promising small molecule HDAC inhibitor being investigated for its role in the treatment of a wide range of solid and hematologic malignancies either as a single-agent, or in combination with other active anti-cancer agents, including 5-FU, carboplatin, paclitaxel, cis-retinoic acid, azacitidine, doxorubicin and Velcade(R) (bortezomib) for Injection. HDAC inhibitors represent a new mechanistic class of anti-cancer therapeutics that target HDAC enzymes and have been shown to: arrest growth of cancer cells (including drug resistant subtypes); induce apoptosis, or programmed cell death; promote differentiation; inhibit angiogenesis; and sensitize cancer cells to overcome drug resistance when used in combination with other anti- cancer agents.

Intravenous belinostat is currently being evaluated in multiple clinical trials as a potential treatment for multiple myeloma, T- and B-cell lymphomas, AML, mesothelioma, liver, soft tissue sarcoma, colorectal, ovarian cancers, either alone or in combination with anti-cancer therapies. An oral formulation of beli
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