Navigation Links
CuraGen Presents Update on Clinical Development Program for,Belinostat

- Clinical activity reported against CTCL, PTCL and Ovarian Cancers -

BRANFORD, Conn., June 12, 2007 /PRNewswire-FirstCall/ -- CuraGen Corporation , a clinical-stage biopharmaceutical company focused on oncology, presented today an update on the clinical development program for belinostat, a histone deacetylase (HDAC) inhibitor, and reported updated results suggesting clinical activity of belinostat against cutaneous T-cell lymphoma (CTCL), peripheral T-cell lymphoma (PTCL), and ovarian cancers.

A conference call is being hosted at 8:30 a.m. Eastern time on June 12, 2007, to review these results including data presented at the 2007 Pan Pacific Lymphoma Conference being held this week in Maui, HI, and data presented at the 2007 American Society of Clinical Oncology (ASCO) meeting.

"We are very impressed by the emerging data on intravenous belinostat in the treatment of solid and hematologic cancers, both as a single agent and in combination with other chemotherapeutic agents. These results, along with additional data actively being generated, are helping us to refine the potential indications for belinostat and to enable us to develop an appropriate plan for our Phase III program," commented Frank Armstrong, M.D., President and Chief Executive Officer of CuraGen.

CLN-6: Phase II trial evaluating intravenous belinostat for T-cell Lymphomas

The interim results reported on 14 patients with CTCL and 12 patients with PTCL. In the CTCL arm in patients who had received an average of six prior lines of therapy, four of 14 patients achieved an objective response for an objective response rate of 29% including one complete response (CR) and three partial responses (PR). Time to response ranged from 8-57 days. As demonstrated by a decrease in SWAT score, 77% of evaluable patients showed an improvement in skin burden of CTCL. Five out of six patients with significant pruritus at baseline had a cl
'"/>




Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. CuraGen and TopoTarget Announce New Clinical Results With Belinostat to be Reported at Upcoming Major Medical Meetings
2. CuraGen Announces New Preclinical Results with Belinostat and Velafermin to be Presented at AACR Annual Meeting
3. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
4. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
5. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
6. SemBioSys Presents Positive Insulin Data at the American Diabetes Association Conference
7. Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis
8. Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis
9. BioLife Solutions Presents Data on CryoStor at International Society for Cellular Therapy Annual Meeting
10. Genaera Presents Preclinical Data on Trodusquemine (MSI-1436) for the Treatment of Obesity at the American Diabetes Association 67th Scientific Session
11. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
Post Your Comments:
(Date:4/17/2015)... 16, 2015 Research and Markets ( ... "Corporate Reputation of Pharma in 2014 - a Perspective ... to their offering. This independent study, funded ... groups with an interest in diabetes on the corporate ... pharma industry as a whole) in 2014. The results ...
(Date:4/17/2015)... , Apr. 16, 2015 Research and ... the addition of the "The Corporate Reputation ... - Global Edition " report to their ... a Patient Perspective, is now in its fourth ... results; published early 2015). For each annual Corporate ...
(Date:4/17/2015)... April 17, 2015 Sigma-Aldrich Corporation ... Science and High Technology company, today announced the ... headquarters and state-of-the-art Cell Culture Technical Center ... facility will provide customized support to meet customer ... "Our new Technical Center will significantly ...
Breaking Medicine Technology:Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 2Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 3Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 4Perspective of Diabetes Patient Groups on the Corporate Reputation of Pharma in 2014: 130 patient groups with an interest in diabetes from 34 countries 5The Corporate Reputation of Pharma - The Global Patient Perspective in 2014 2Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 2Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 3Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 4Sigma-Aldrich Expands Customer-Centric Model with Investments in Singapore That Localize World-Class Capabilities to Better Support Customers in Asia 5
(Date:4/18/2015)... NE (PRWEB) April 18, 2015 ... in healthcare staffing, including physical therapy jobs, has ... at the South Carolina Physical Therapy Association Annual ... the Kroc Center in Greenville, SC. , ... opportunities, and exhibits with products and services. ...
(Date:4/17/2015)... John Evans, a Gardant affordable assisted ... from 2 p.m. to 3 p.m. on April 24. ... Ct. in Pekin, Illinois, serves older adults of all ... to maintain their independence. , Becky Baker will entertain ... be served during the luau. , For more information, ...
(Date:4/17/2015)... 2015 Florida Hospital Wesley Chapel, Florida ... Hospital Carrollwood were all selected as Top Workplaces in ... Pasco County, is ranked number one for large businesses ... was conducted in partnership with an independent research firm. ... hospital that opened in October of 2012 with a ...
(Date:4/17/2015)... 2015 Representatives Jim Himes (D-CT) and ... Act HR 1849 in congress on April 16, 2015 ... for patients with the genetic disease. , The ... be the first to create a federally led and ... hereditary hemorrhagic telangiectasia. This would effectively prevent premature death ...
(Date:4/17/2015)... York, New York (PRWEB) April 17, 2015 ... that allege this class of prescription medications ... a heart attack, stroke or other life-threatening cardiovascular ... underway in U.S. District Court, Northern District of ... by the U.S. Judicial Panel on Multidistrict Litigation ...
Breaking Medicine News(10 mins):Health News:Healthcare Staffing Leader, Aureus Medical Group, to Exhibit at the South Carolina Physical Therapy Association Annual Conference 2Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 2Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 3Health News:Tampa Bay Times Selects Florida Hospital Wesley Chapel, Florida Hospital at Connerton Long Term Acute Care and Florida Hospital Carrollwood As Top Workplaces in Tampa Bay 4Health News:House Representatives Introduce Bill to Fight Genetic Disease 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 3Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 4
... "Addiction is on the upswing, fueled by pressures from our ... Phoenix House , the nation,s largest non-profit alcohol and ... of the population feels that drug abuse is at either serious ... having on individuals, families, and communities ." ...
... is a devastating disease with poor prognosis. This ... therapy. However, clinical studies have demonstrated poor efficacy ... of adenoviral binding sites on pancreatic cancer cells ... Circumventing CAR-mediated entry therefore seems a promising option ...
... 2009Children who live in Afghanistan are particularly affected every day ... likelihood of developing PTSD: trauma, child labor, and family and ... to the bombings, abuse, and the general upheaval of their ... the effects of long-term poverty and familial turmoil. The ...
... LOUISVILLE, Colo. and TORONTO, June 23 /PRNewswire/ -- ... a strategic alliance to create a global standards-based product ... to dramatically improve the accuracy and clarity of electronic ... of healthcare and pharmaceutical products and, in turn, to ...
... provides pointers for better food choices for kids , ... summer, children dive into the pool, head to the park, ... so, they may also leave nutrition behind; nutrition essential to ... and nutrition expert Chere Bork, a registered dietitian with more ...
... ... Wizard Feature for its Asset Tracking Application, Passport Assets, Enabling its Customers to Develop Custom ... ... -- ASAP Systems today announced the release of a depreciation wizard feature for ...
Cached Medicine News:Health News:America's Silent Crisis: Addiction -- Downturn Fuels Rising Drug and Alcohol Abuse, Phoenix House Study Reveals 2Health News:America's Silent Crisis: Addiction -- Downturn Fuels Rising Drug and Alcohol Abuse, Phoenix House Study Reveals 3Health News:Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells 2Health News:Afghani children suffering from post-traumatic stress 2Health News:GS1 Canada and GHX Align to Make Canada's Healthcare Supply Chain More Efficient and Effective 2Health News:GS1 Canada and GHX Align to Make Canada's Healthcare Supply Chain More Efficient and Effective 3Health News:GS1 Canada and GHX Align to Make Canada's Healthcare Supply Chain More Efficient and Effective 4Health News:Summer is Here! Top Five Tips for Making Your Child's Summer Eating Habits Healthier 2Health News:ASAP Systems Launches New Depreciation Feature Enabling its Customers to Develop Custom Formulas to Calculate Depreciation Of Their Fixed Assets Inventory 2
Rees bayonet forceps, standard, 5-1/2", TC....
... designed to accept rigid fixation ... an excellent reconstructive option for ... blowout defects. Each design has ... one or more rigid fixation ...
Medpor Complete Orbit are designed to replace non load bearing bony structures in the orbital area....
... implant can provide up to 5mm of ... trimmed to meet the needs of the ... to rest on the most anterior aspect ... easier positioning of the implant and a ...
Medicine Products: