Navigation Links
Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR,Annual Meeting Late-Breaking Clinical Trials Session

e 20 evaluable patients with measurable tumor lesions, treatment with CB7630 resulted in partial radiological responses (as measured by the RECIST criteria) in 11 patients (55%), with 7 patients demonstrating ongoing stable disease and 3 patients experienced regressing bone disease. Individual patients treated with CB7630 also experienced improvement in pain and a reduction in opioid use. Circulating tumor cells (CTC) were detected in 14 of 31 patients and changes in CTC counts were shown to correlate with changes in PSA.

Currently 27 (90%) of the 30 patients in the Phase I/II trial remain on study and continue to be treated with CB7630. Of the 15 patients in the Phase I portion of the trial, 12 patients (80%) are still receiving treatment with CB7630, with the average patient having received the drug for over 8.5 months and 4 patients having received the drug for over 12 months.

Abiraterone, an oral, irreversible CYP450c17 enzyme inhibitor appears to have activity in post-docetaxel castration refractory prostate cancer patients

The Phase II trial is being conducted at numerous locations in the United States and United Kingdom. In the trial, CB7630 is administered orally, once daily, to patients with castration refractory prostate cancer who have failed treatment with first line docetaxel based chemotherapy. The oral presentation was made by Dr. Alison H. M. Reid from The Institute of Cancer Research.

To date, 19 patients have been treated in this Phase II trial, with 13 of the patients having been treated for over 3 months. Of the 19 patients who have been treated, CB7630 was well tolerated with only minimal toxicity in this post-docetaxel population. In the 13 patients who have been on study for over 3 months, 8 patients (62%) experienced confirmed declines in PSA levels of greater than 50%, with 2 of the 13 patients (15%) experiencing PSA declines of greater than 90%. All 19 patients in this trial are still receiving treatment with CB7
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
2. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ASCO Annual Meeting
3. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at AUA Annual Meeting
4. Generex Biotechnology to Make Presentations At 46th Annual Meeting of the European Society of Pediatric Endocrinology
5. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
6. Beike Biotechnology Study Suggests Adult Stem Cells Show Promise for Peripheral Vascular Disease
7. Prana Biotechnology Presents New Key Findings on PBT2
8. Generex Biotechnology Vaccine Strategy Presented at International Conference in London
9. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
10. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
11. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
Post Your Comments:
(Date:6/18/2013)... PROSPECT, Ill. , June 18, 2013 /PRNewswire-iReach/ ... of its new X3130 Appliance Inlet Module. The ... circuit breaker , combines a C14 appliance inlet ... one compact package.  This three-in-one device allows design ... their designs - cutting installation time by 66 ...
(Date:6/18/2013)... Mass. , June 18, 2013 ... the company was named Overall Performance Leader in Imaging ... Equipment & Infrastructure report. Philips also received Best in ... its imaging products: Ingenuity Core 128 Computed Tomography ... ultrasound and PageWriter TC70 cardiograph. The annual Best in ...
(Date:6/18/2013)... 18, 2013 Unilife Corporation ("Unilife" or "Company") ... and manufacturer of injectable drug delivery systems, today announced ... www.unilife.com . The new site includes additional products, videos, ... on a regular basis. Mr. Alan ... emerging global leader for injectable drug delivery systems, we ...
Breaking Medicine Technology:Three-in-One X3130 Appliance Inlet Module 2Philips Named 2013 Overall Performance Leader In Imaging Equipment By KLAS 2Unilife Launches New Corporate Website 2
... Inc. (Nasdaq: MSHL ), an oncology company ... cancer metabolism, announced today that it has filed a ... Exchange Commission for a rights offering to existing stockholders ... stock. The Company will announce further details regarding the ...
... Feb. 21, 2012  Isis Pharmaceuticals, Inc. (Nasdaq: ISIS ... will present a company overview at Citi,s 2012 Global Health ... ET at the Waldorf Astoria in New York City. ... available on the "Investors & Media" section of the Company,s ...
Cached Medicine Technology:Marshall Edwards Announces Rights Offering to Stockholders 2Marshall Edwards Announces Rights Offering to Stockholders 3
(Date:6/19/2013)... Francisco, CA (PRWEB) June 19, 2013 The ... sized tents is because users can place a 4x8 flood ... clearance boundary space to work around. In addition, Gorilla ... tents. Because they are the tallest, thickest and strongest grow ... new bar for grow tent standards. , Gorilla ...
(Date:6/19/2013)... The website HealthNewsWires.com has recently published an informative ... and tips to manage and prevent the condition. , ... author defines insulin resistance as a condition ... glucose from the bloodstream. Glucose, or blood sugar, ... and systems of the body for normal function. ...
(Date:6/19/2013)... Forney,TX (PRWEB) June 19, 2013 Tornadoes ... this year. Many families who have fallen victim to ... Radius Engineering International Inc. has protected families and ... years. Radius Engineering International Inc. believes in the philosophy ... below the water table, that allows people to stand ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 In honor ... Vein Specialists is providing information that women can use ... . , Pregnant women should pay close attention to ... their babies. “The changes a woman’s body undergoes while ... including varicose veins,” says Dr. Ray Workman, a leading ...
(Date:6/19/2013)... (PRWEB) June 19, 2013 Health ... the history of managed care. As many as ... through the new state-based and federally operated marketplaces. ... essential health benefits, and examples of premium rates ... industry-leading health business information publisher Atlantic Information Services’s ...
Breaking Medicine News(10 mins):Health News:Stealth Grow Tent Brand’s Popularity Rises 2Health News:Effects of Insulin Resistance and How to Increase Insulin Sensitivity Published in New Video by Health News Wire 2Health News:Radius Engineering International Inc. Tornado-Resistant Storm Shelters 2Health News:Novant Health Vein Specialists Promotes Women’s Health with Social Media Campaign 2Health News:New Special Report Provides Comprehensive Overview of New Health Insurance Exchange Marketplaces 2
... 24 (HealthDay News) -- Exclusive breast-feeding of infants for ... developing the itchy skin disorder known as eczema in ... infant receives only breast milk, with no additional food ... breast-feeding up to 6 months of age is recommended ...
... York, NY, August 24, 2011 Nearly three-quarters (72%) of people ... over the last two years said that they skipped needed ... cost, according to a new Commonwealth Fund report. The ... debt, compared to about half (49%) who lost jobs but ...
... , Governments in the UK, US and Canada are undermining ... smoking, a report by public health researchers says. The paper, ... argues that films with tobacco imagery should be ineligible for ... conflict with public health goals. Earlier research shows that ...
... News) -- Accidental exposure to highly toxic chemotherapy drugs ... a new study finds. Researchers surveyed 1,339 oncology ... infusion centers and found that nearly 17 percent said ... drugs. In the United States, about 84 percent ...
... HealthDay Reporter , TUESDAY, Aug. 23 (HealthDay News) ... jobless men in what,s been dubbed the "mancession" are ... support their working partners, a small study suggests. ... conducted intensive interviews of 19 recently unemployed men. She ...
... , TUESDAY, Aug. 23 (HealthDay News) -- A common ... worsen over time and may lead to an increased risk ... diastolic dysfunction, which often comes with advancing age, the heart,s ... and is accompanied by elevated filling pressures. The new ...
Cached Medicine News:Health News:Breast-Feeding Won't Prevent Kids' Eczema, Researchers Say 2Health News:Three quarters of those who have lost jobs and health insurance are skipping needed health care 2Health News:Three quarters of those who have lost jobs and health insurance are skipping needed health care 3Health News:Three quarters of those who have lost jobs and health insurance are skipping needed health care 4Health News:Government subsidies to the US film industry promote youth smoking, argue researchers 2Health News:Nurses at Risk for Accidental Exposure to Chemo Drugs: Study 2Health News:In Tough Times, Jobless Men Embrace Housework 2Health News:In Tough Times, Jobless Men Embrace Housework 3Health News:Common Heart Dysfunction Can Help Bring on Heart Failure 2
... display of corneal layers: endothelium, ... epithelial layers. Accurate analysis of ... keratocytes, nerve fibres, basal & ... surgery and pathology: optical pachymetry, ...
The Ahmed Glaucoma Valve has been successfully demonstrated to work in all types of glaucoma cases, particularly neovascular, congenital and uvietic glaucoma....
Ahmed Glaucoma Valve with Pars Plana Clip....
Ahmed Glaucoma Valve Flexible Plate ....
Medicine Products: