Navigation Links
Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR,Annual Meeting Late-Breaking Clinical Trials Session

LOS ANGELES--(BUSINESS WIRE)--Apr 17, 2007 - Cougar Biotechnology, Inc. (OTCBB:CGRB) today announced that positive Phase I and Phase II data on the Company's prostate cancer drug candidate CB7630 (abiraterone acetate) was presented at the American Association for Cancer Research (AACR) Annual Meeting in Los Angeles, California. The data was presented in two oral presentations as part of a special session, Phase II Proof of Concept Late-Breaking Clinical Trials. These presentations are further detailed below:

Inhibition of androgen synthesis results in a high response rate in castration refractory prostate cancer: A Phase II clinical trial

The Phase I/II trial of CB7630 was conducted at The Institute of Cancer Research and at The Royal Marsden NHS Foundation Trust in the United Kingdom. In the trial, CB7630 was administered orally, once daily, to chemotherapy-naive patients with castration refractory prostate cancer (CRPC), who had progressive disease despite treatment with LHRH analogues and multiple other hormonal therapies, including antiandrogens, diethylstilboestrol and dexamethasone. To date a total of 38 patients have been treated in the Phase I/II trial, including 15 patients treated in the Phase I portion of the trial and 23 patients treated in the Phase II portion of the trial. In his oral presentation, Dr. Gerhardt Attard from The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust in the United Kingdom reported that in the 38 patients treated in this trial, CB7630 was well tolerated at doses as high as 2000 mg/day with minimal toxicity. Moreover, no dose limiting toxicity has been observed in the trial to date.

Of the 30 patients who were evaluable in the Phase I/II trial, 18 patients (60%) experienced confirmed declines in prostate specific antigen (PSA) levels of greater than 50%, with 10 of the 30 patients (33%) experiencing PSA declines of greater than 90%. Of th
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
2. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ASCO Annual Meeting
3. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at AUA Annual Meeting
4. Generex Biotechnology to Make Presentations At 46th Annual Meeting of the European Society of Pediatric Endocrinology
5. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
6. Beike Biotechnology Study Suggests Adult Stem Cells Show Promise for Peripheral Vascular Disease
7. Prana Biotechnology Presents New Key Findings on PBT2
8. Generex Biotechnology Vaccine Strategy Presented at International Conference in London
9. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
10. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
11. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
Post Your Comments:
(Date:8/28/2015)... N.J. , Aug. 28, 2015  IP Shakti, LLC, ... LLC. ... "Our new corporate identity signifies our transformation ... world,s first predictive analytics platform for patent claim validity." ... the launch of the proprietary AIA Shield™ platform, the Company ...
(Date:8/28/2015)... Denmark and ATLANTA , ... 2015 the US Food and Drug Administration (FDA) cleared the ... Disorder in adult patients who have failed to receive satisfactory ... is a non-invasive technique for stimulating neural tissue in the ... Depressive Disorder. The procedure has been proven safe and effective ...
(Date:8/28/2015)... August 28, 2015 The report "Eubiotics Market by ... Poultry, Ruminant, and Aquaculture), & by Region ( North ... Asia-Pacific , and Rest of the World) - Global ... market for Eubiotics was valued at USD 4.62 Billion in ... 2020, at a CAGR of 7.4% from 2015 to 2020. ...
Breaking Medicine Technology:IP Shakti, LLC Changes Company Name to Prediqtus, LLC 2Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 2Therapy System for Treating Major Depressive Disorder Receives FDA Clearance 3Eubiotics Market Worth 7.05 Billion USD by 2020 2Eubiotics Market Worth 7.05 Billion USD by 2020 3Eubiotics Market Worth 7.05 Billion USD by 2020 4Eubiotics Market Worth 7.05 Billion USD by 2020 5
... BARCELONA, Spain , June 1 Clinicians at Institut Catala ... in Spain using RapidArc® radiotherapy from Varian Medical Systems (NYSE: ... the first patient in the country to receive the fast and efficient ... "The treatment went ...
... BEIJING , June 1 /PRNewswire-Asia/ -- Sinovac Biotech Ltd. (Nasdaq: ... it has received,the confirmation from the China International Tendering Company that Sinovac,was ... supply the Company,s hepatitis A vaccine, Healive, to the,Beijing Expanded Program of ... ...
Cached Medicine Technology:Prostate Cancer Patient First in Spain to Receive Fast and Precise RapidArc(R) Radiotherapy Treatment from Varian 2Prostate Cancer Patient First in Spain to Receive Fast and Precise RapidArc(R) Radiotherapy Treatment from Varian 3Prostate Cancer Patient First in Spain to Receive Fast and Precise RapidArc(R) Radiotherapy Treatment from Varian 4Sinovac Selected by Beijing CDC to Supply Hepatitis A Vaccine Healive(R) 2Sinovac Selected by Beijing CDC to Supply Hepatitis A Vaccine Healive(R) 3
(Date:8/29/2015)... ... August 29, 2015 , ... ... may extend and improve the lives of patients, according to a newly published ... here to read the full article. , The authors of the new ...
(Date:8/29/2015)... ... ... ProDrop Particles includes over 40 particle backdrops designed for use in ... users can shrink and stretch in the Final Cut Pro X timeline. Choose from ... scale, speed, range, and flare attributes with intuitive controls found in the top-right inspector ...
(Date:8/29/2015)... Houston, TX (PRWEB) , ... August 29, 2015 ... ... settlement allows the company to freely market and sell Arterosil and Arterosil HP, ... Daniels Health Sciences, LLC (DHS) sued Vascular Health Sciences, LLC (VHS) in the ...
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... ... No Malaria Day at the Zoo to celebrate children helping children, a thank ... their congregations throughout West Ohio have contributed to the United Methodist initiative to ...
(Date:8/28/2015)... ... 28, 2015 , ... For Dallas, the time is nearing for the annual ... Tenet Health. , The American Heart Association hosts their well-known Heart Walk to raise ... together, a difference can be made. Walkers can participate in the cause and someone ...
Breaking Medicine News(10 mins):Health News:Top Mesothelioma Researchers Highlight Targeted Therapies in New Report, According to Surviving Mesothelioma 2Health News:FCPX Effects Developer, Pixel Film Studios, Releases ProDrop Particles. 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 2Health News:Saturday’s United Methodist Event at Columbus Zoo Celebrates Imagine No Malaria 3Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2
... The American Lung Association in Iowa is happy to report ... Family Smoking Prevention and Tobacco Control Act (HR 1256) today. ... applauds Senators Tom Harkin and Chuck Grassley for playing instrumental roles ... the Family Smoking Prevention and Tobacco Control Act. This important legislation ...
... June 11 The Campaign for Tobacco-Free Kids applauds ... today to approve historic legislation that gives the U.S. ... products, including the authority to crack down on tobacco ... the bipartisan bill 79 to 17. The House has ...
... Kids applauds U.S. Senators Judd Gregg and Jeanne Shaheen for ... Food and Drug Administration (FDA) authority to regulate tobacco products, ... sales to kids. The U.S. Senate approved the bipartisan ... legislation, and Congress is expected to quickly send a final ...
... The Campaign for Tobacco-Free Kids applauds U.S. Senator Sherrod Brown ... historic legislation that gives the U.S. Food and Drug Administration ... crack down on tobacco marketing and sales to kids. ... 17. The House has approved similar legislation, and Congress ...
... , WASHINGTON, June 11 The Campaign for ... for voting today to approve historic legislation that gives the ... products, including the authority to crack down on tobacco marketing ... bipartisan bill 79 to 17. The House has approved ...
... June 11 Oclaro, Inc. (Nasdaq: OCLR ... has entered the eye-safe wavelength market with laser diode ... micrometer (um). The new long-wavelength devices target eye-safe applications ... , Eye-safe standards are important in environments where there ...
Cached Medicine News:Health News:Senators Harkin and Grassley Vote to Protect America's Kids from Tobacco 2Health News:Senators Harkin and Grassley Vote to Protect America's Kids from Tobacco 3Health News:Senators Gregg and Shaheen Vote to Protect America's Kids From Tobacco 2Health News:Senator Brown Leads Fight to Protect America's Kids from Tobacco 2Health News:Senators Murkowski and Begich Vote to Protect America's Kids from Tobacco 2Health News:Oclaro Launches Eye-Safe High Power Laser Diodes at LASER 2009 2Health News:Oclaro Launches Eye-Safe High Power Laser Diodes at LASER 2009 3
... a FAM-labeled probe that is designed to detect ... In addition, this ASR contains primers, a Texas ... sequence. This ASR requires an instrument that can ... as the Cepheid SmartCycler System. The Cepheid Analyte ...
... SpideRX Embolic Protection Device features the ability ... cross the lesion and a pre-loaded nitinol ... and recovery. Offering a fully rapid exchange ... use in the indicated applications:, Carotid Indication ...
Pefakit PiCT DxS Diluent for Determination of Total Heparin...
Controls for APC Resistance / Factor V Leiden Functional Assay...
Medicine Products: