Navigation Links
Cougar Biotechnology Announces Presentation of Positive CB7630,Clinical Data at ASCO Annual Meeting

LOS ANGELES--(BUSINESS WIRE)--Jun 4, 2007 - Cougar Biotechnology, Inc. (OTCBB: CGRB) today announced that positive interim Phase I and Phase II data on the Company's prostate cancer drug candidate CB7630 (abiraterone acetate) was presented at the American Society of Clinical Oncology (ASCO) Annual Meeting, which is currently taking place in Chicago, Illinois. The data was presented in two poster presentations on Saturday, June 2nd, as part of the poster discussion session for genitourinary (prostate) cancer that took place. The poster presentations are further detailed below:

Phase I/II Study of Continuous Oral Dosing of an Irreversible CYP17 Inhibitor, Abiraterone, in Castration-Resistant Prostate Cancer Patients Incorporating the Evaluation of Androgens and Steroid Metabolites in Plasma and Tumor and the Study of Circulating Tumor Cells

The Phase I/II trial of CB7630 was conducted at The Institute of Cancer Research and at The Royal Marsden NHS Foundation Trust in the United Kingdom. In the trial, CB7630 was administered orally, once daily, to chemotherapy-naive patients with castration resistant prostate cancer (CRPC), who had progressive disease despite treatment with LHRH analogues and multiple other hormonal therapies, including antiandrogens, diethylstilboestrol and dexamethasone. To date, a total of 42 patients have been treated in the Phase I/II trial, including 15 patients treated in the Phase I stage of the trial and 27 patients treated in the Phase II stage of the trial. In his poster presentation, Dr. Gerhardt Attard from The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust in the United Kingdom reported that in the 42 patients treated in this trial, CB7630 was well tolerated at doses as high as 2000 mg/day with minimal toxicity. Moreover, no dose limiting toxicity has been observed in the trial to date.

In the 34 patients who were evaluable for response in the
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
2. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at AUA Annual Meeting
3. Cougar Biotechnology Presents Positive CB7630 Clinical Data at AACR Annual Meeting Late-Breaking Clinical Trials Session
4. Generex Biotechnology to Make Presentations At 46th Annual Meeting of the European Society of Pediatric Endocrinology
5. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
6. Beike Biotechnology Study Suggests Adult Stem Cells Show Promise for Peripheral Vascular Disease
7. Prana Biotechnology Presents New Key Findings on PBT2
8. Generex Biotechnology Vaccine Strategy Presented at International Conference in London
9. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
10. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
11. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
Post Your Comments:
(Date:2/27/2015)... and HOUSTON, TX , Feb. 27, ... (TSX-V: EPI) and Bloom Burton & Co. Ltd. ("Bloom ... contractual lock-up (the "Lock-Up") 2,353,130 common shares of the ... originally subject to the Lock-Up. Of the Common Shares ... trading immediately upon release from the Lock-Up while the ...
(Date:2/27/2015)... Feb. 27, 2015  In recognition of Rare Disease ... the global bleeding disorders community, CSL Behring ... units (IUs) of protein therapies to the World Federation ... organization which has worked to improve the lives of ... donation supports the WFH,s Global Alliance for Progress (GAP) ...
(Date:2/27/2015)... , Feb. 27, 2015  Uroplasty, Inc. (NASDAQ: ... and markets innovative proprietary products to treat voiding dysfunctions, ... Annual ROTH Conference on Tuesday, March 10, 2015. ... Reynolds , Chief Financial Officer, will present at 4:00 ... one at the conference at the Ritz Carlton in ...
Breaking Medicine Technology:ESSA Pharma and Bloom Burton announce additional release of shares from voluntary lock-up agreement 2ESSA Pharma and Bloom Burton announce additional release of shares from voluntary lock-up agreement 3ESSA Pharma and Bloom Burton announce additional release of shares from voluntary lock-up agreement 4CSL Behring Continues Treatment Access Leadership by Donating Bleeding Disorder Protein Therapies IUs to World Federation of Hemophilia 2CSL Behring Continues Treatment Access Leadership by Donating Bleeding Disorder Protein Therapies IUs to World Federation of Hemophilia 3Uroplasty to Participate in the 27th Annual ROTH Conference 2
... , WILMINGTON, Del. ... System is taking a giant leap forward toward a ... Order Entry (CPOE), technology that makes it easier, more efficient ... (Logo: http://www.newscom.com/cgi-bin/prnh/20090407/DC95299LOGO ) , The system goes live on ...
... , HOFFMAN ESTATES, Ill. , Jan. 28 ... Drug Administration (FDA) has given 510(k) marketing clearance to both ... , The DYNA-LINK system features a next-generation stand-alone device that ... is a thoracolumbar plating system that features multiple types of ...
Cached Medicine Technology:Christiana Care Health System Rolls Out Electronic Computerized Provider Order Entry 2
(Date:2/27/2015)... Dr. Andrew Campbell, one of the ... announce the expansion of Quintessa Aesthetic Center with a ... begun seeing patients on February 18, 2015. , According ... a variety of state-of-the-art surgical and non-surgical procedures ... peels, chemical peels, microdermabrasion, ProFractional Laser, Broad Band Light, ...
(Date:2/27/2015)... (PRWEB) February 27, 2015 Winter is here, ... on human skin, exposure to snow and ice can be ... also hurt dogs’ paws. The Puppy Store is ready to ... keep their dogs safe in the winter time. , Ice ... vomiting, diarrhea and other symptoms. Ingestion of ice melt products ...
(Date:2/27/2015)... Florida Hospital North Pinellas is being ... Gold Plus hospital. In order to receive the award, ... to all Get With The Guidelines - Stroke Quality ... and achieved 75-percent or higher compliance with six of ... These are reporting initiatives to measure quality of care. ...
(Date:2/27/2015)... February 27, 2015 Healthpointe is ... suffered from injuries or diseases affecting the ... physicians are located throughout Southern California, and are ... to treat conditions related to the upper extremities. ... M. Ashley are board-certified and fully trained in ...
(Date:2/27/2015)... 27, 2015 Mirena IUD lawsuits ( ... allegedly suffered uterine perforations and other serious harm due ... to move forward in the multicounty litigation underway in ... reports. Court records indicate that the proceeding’s 34th ... a Conference convened that same day. (In Re: Mirena ...
Breaking Medicine News(10 mins):Health News:Dr. Andrew Campbell Expands Quintessa Aesthetic Center into Delafield 2Health News:Dr. Andrew Campbell Expands Quintessa Aesthetic Center into Delafield 3Health News:The Puppy Store Helps Dogs Prepare for Harsh Winter Conditions 2Health News:Florida Hospital North Pinellas Receives Get With The Guidelines - Stroke Gold Plus Quality Achievement Award 2Health News:Healthpointe is Now Performing Arthroscopic Surgery Techniques for Elbow, Hand and Wrist Injuries and Diseases, such as certain Ganglion Cysts 2Health News:Mirena Lawsuits Progress in New Jersey with Issuance of New Case Management Order, Bernstein Liebhard LLP Reports 2Health News:Mirena Lawsuits Progress in New Jersey with Issuance of New Case Management Order, Bernstein Liebhard LLP Reports 3
... services available for all Minnesotans, MINNEAPOLIS, Feb. 14 ... day such as a birthday or holiday as a ... the perfect day to,quit smoking for that special someone, ... QUITPLAN Services from ClearWay,Minnesota(SM)., Some romantic benefits of ...
... Company Recognized for Outstanding Sales Achievement, PARAMUS, N.J., ... and Earth Balance(R) heart healthy food products,and other established ... Award (MVP) by Refrigerated & Frozen Foods Retailer magazine. ... refrigerated and frozen,food supplier with the largest percentage gain ...
... (Nasdaq: DATA ), a technology company focused ... today reported that it will be,presenting at the ... at the Ritz Carlton in Laguna Niguel, California, ... on Wednesday afternoon,February 20th at 2:30 P.M., Pacific ...
... Today Digital Healthcare,Systems filed to enjoin the Ohio ... of Jobs and Family Services (ODJFS),regarding a state-issued ... in health insurance administration that settles which insurers,are ... Healthcare, headquartered in Cleveland, filed the petition in,the ...
... in scorpion venom that may hold the key to ... , In the December 28 issue of the Journal ... how this novel peptide, called GaTx1, can control the ... interacting with a crucial chloride channel. This research was ...
... new water purification,technology by Reliance Products L.P., one ... products, and Procter & Gamble (NYSE: PG ... United States. The,product, PUR(TM) Purifier of Water ( ... designed for outdoor recreation,and emergency preparedness use. PUR ...
Cached Medicine News:Health News:QUITPLAN(R) Services Can Help Make Valentine's Day Smoke-Free 2Health News:QUITPLAN(R) Services Can Help Make Valentine's Day Smoke-Free 3Health News:Smart Balance(R) Named MVP in Refrigerated & Frozen Foods Retailer Product Lineup 2Health News:DATATRAK to Present at the Roth Capital Partners 20th Annual Orange County Stock Conference 2Health News:DATATRAK to Present at the Roth Capital Partners 20th Annual Orange County Stock Conference 3Health News:Digital Healthcare Files to Enjoin Two State of Ohio Departments; Charges Bid-Steering and Breach of Agreement in Program to Control Medicaid Overpayment of Insurance Claims 2Health News:Peptide discovered in scorpion venom may hold key to secretory diseases 2Health News:Peptide discovered in scorpion venom may hold key to secretory diseases 3Health News:New Water Purification Product from Reliance Products and Procter & Gamble now Available in Retail Stores 2Health News:New Water Purification Product from Reliance Products and Procter & Gamble now Available in Retail Stores 3
... The HOPE continuous nebulizer is improved CNBT technology, ... of remixing SVNs every 15 minutes. HOPE allows ... to eight hours. Heliox administration couldn't be easier, ... tank of Heliox, you can turn the HOPE ...
... Thera-Mist® Air Entrainment Nebulizers deliver particulate ... range for your chronic secretion patients. For ... with your existing supply of sterile water., ... operates at FiO2's of 20-50% with a ...
Rotary Piston Mini Nebulizer...
Lumitex® LightMat® Surgical Illuminator improves visualization in deep cavity surgery. Flexible and malleable, it attaches easily to most retractors, bringing bright, cool area lighting where...
Medicine Products: