Navigation Links
Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III,Data with Rifamycin MMX in Infectious Diarrhea

-- Primary endpoint achieved --

LAINATE, Italy - July 4, 2007 - Cosmo Pharmaceuticals SpA (SWX:COPN) announced today positive preliminary results from its phase II/III study with CB-01-11 (Rifamycin SV MMX(tm)) in infectious diarrhoea. CB-01-11 is a broad spectrum, semi-synthetic antibiotic that is not absorbed when taken in tablet form. Through the use of Cosmo's MMX(tm) technology, which delivers the active ingredient into the colon, bacteria in the gastro intestinal tract that are important for vitamin synthesis are not sterilized. Given that it is practically not absorbed CB-01-11 is potentially applicable for the treatment of long term infections in the colon.

In the placebo controlled, randomized, double blind trial 120 patients in 8 sites in South Africa were treated with a 200mg tablet, 4 times per day for 3 days. The trial assessed non-inferiority versus Normix® (rifaximin) and the primary endpoint was the time from first ingestion of tablet to the last unformed stool. According to the preliminary reports CB-01-11 met this primary endpoint.

Mauro Ajani, CEO of Cosmo Pharmaceuticals, commented: "We are very encouraged about these preliminary results since many of the needs of patients are not adequately met with products currently on the market. Infections of the colon affect many more persons than colon inflammations and this is consequently a substantially larger market. We believe that our proprietary MMX(tm) technology will enable us to improve a range of products in colon infections and thus better meet patients' requirements."

Further analysis of the data is ongoing.

About Cosmo Pharmaceuticals

Cosmo is a speciality pharma company that aims to become a global leader in optimised therapies for certain gastrointestinal diseases. The com­pany's proprietary clinical development pipeline specifically addresses innovative treatments for IBD, such as ulce rative colitis and Crohn's disease, and colon infections. Cosmo's first MMX(tm) product that has reached the market is LIALDA(tm) / MEZAVANT(tm), a treatment for IBD that is licensed globally to Giuliani and Shire Pharmaceuticals. Cosmo's proprietary MMX(tm) technology is at the core of the company's product pipeline and was developed from its expertise in formulating and manufacturing gastrointestinal drugs for international clients at its GMP (Good Manufacturing Practice) facilities in Lainate, Italy. For further information on Cosmo, please visit the Company's website: www.cosmopharmaceuticals.com

Contact:

Dr. Chris Tanner, CFO and Head of Investor Relations

Cosmo Pharmaceuticals SpA

Tel: +39 02 9333 7614

Some of the information contained in this press release contains forward-looking statements. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those in the forward-looking statements as a result of various factors. Cosmo undertakes no obligation to publicly update or revise any forward-looking statements.

Claire Rowell Manager Financial Communications

Holborn Gate, 26 Southampton Buildings London, WC2A 1PB

T +44 (0)20 7269 7285 F +44 (0)20 7242 8695

www.fd.com

London, New York, Bahrain, Beijing, Boston, Cape Town, Chicago, Dubai, Dublin, Frankfurt, Hong Kong, Johannesburg, Manchester, Moscow, Paris, San Francisco, Stockholm and Washington.


'"/>




Related medicine technology :

1. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
2. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
3. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
4. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
5. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
6. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
7. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
8. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
9. Cyclacel Pharmaceuticals Announces Results of Phase II Seliciclib Combination Studies
10. Arisaph Pharmaceuticals Announces Results of its Potent Smart DPP-4 Inhibitor, ARI-2243, at the ADA
11. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2019)... Ariz. (PRWEB) , ... January 14, 2019 , ... ... first round of grants, totaling $665,400, to 16 U.S.-based 501(c)(3) nonprofits that align ... education for all, and aid for those affected by natural disasters. Located in ...
(Date:1/14/2019)... BOLOGNA, Italy (PRWEB) , ... January 13, 2019 ... ... automatic data capture and process automation markets, is extremely proud to announce the ... 2D hand held readers for general purpose applications, that now offers both wireless ...
(Date:1/11/2019)... ... 2019 , ... Proven entrepreneur Tony Hartl announced today a new plan to ... who previously built the Planet Tan brand into a multimillion-dollar empire, has ... , “It’s why I came out of retirement after 10 years,” said Hartl. “To ...
Breaking Medicine Technology:
(Date:1/14/2019)... CHURCH, Va. (PRWEB) , ... January 15, 2019 , ... ... ends on Jan. 22 , Risk management is just plain hard, complicated, conflicted, confusing. ... While the changes in the process are not intended as “major”, the new standard ...
(Date:1/14/2019)... (PRWEB) , ... January 14, 2019 , ... NJ Top Docs Proudly Presents All Reviewed & Approved Living Well Providers of 2019. , Acupuncture, ... , Dr. Edward Izrailov - Maplewood , Dr. Joanna Jodar - Somerset , ... Dr. Robert Lenahan - Point Pleasant , Dr. Robert J. Reinhardt - Pequannock , ...
(Date:1/13/2019)... ... January 12, 2019 , ... ... in conjunction with Temple University hosted a continuing education (CEU) event entitled, Can ... The event aimed to create a series of talks to help develop and ...
(Date:1/11/2019)... ... January 11, 2019 , ... ... finalist teams in its “Next Generation Captive Insurance Solutions for New Risk Challenges” ... Solutions. , The three finalist teams are: , ...
(Date:1/10/2019)... ... January 10, 2019 , ... Mount Sinai ... Music Society at the United Nations Staff Recreation Council in support of the ... provide complementary services including music, art, massage, and pet therapies to increase the ...
Breaking Medicine News(10 mins):