Navigation Links
Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III,Data with Rifamycin MMX in Infectious Diarrhea

-- Primary endpoint achieved --

LAINATE, Italy - July 4, 2007 - Cosmo Pharmaceuticals SpA (SWX:COPN) announced today positive preliminary results from its phase II/III study with CB-01-11 (Rifamycin SV MMX(tm)) in infectious diarrhoea. CB-01-11 is a broad spectrum, semi-synthetic antibiotic that is not absorbed when taken in tablet form. Through the use of Cosmo's MMX(tm) technology, which delivers the active ingredient into the colon, bacteria in the gastro intestinal tract that are important for vitamin synthesis are not sterilized. Given that it is practically not absorbed CB-01-11 is potentially applicable for the treatment of long term infections in the colon.

In the placebo controlled, randomized, double blind trial 120 patients in 8 sites in South Africa were treated with a 200mg tablet, 4 times per day for 3 days. The trial assessed non-inferiority versus Normix® (rifaximin) and the primary endpoint was the time from first ingestion of tablet to the last unformed stool. According to the preliminary reports CB-01-11 met this primary endpoint.

Mauro Ajani, CEO of Cosmo Pharmaceuticals, commented: "We are very encouraged about these preliminary results since many of the needs of patients are not adequately met with products currently on the market. Infections of the colon affect many more persons than colon inflammations and this is consequently a substantially larger market. We believe that our proprietary MMX(tm) technology will enable us to improve a range of products in colon infections and thus better meet patients' requirements."

Further analysis of the data is ongoing.

About Cosmo Pharmaceuticals

Cosmo is a speciality pharma company that aims to become a global leader in optimised therapies for certain gastrointestinal diseases. The com­pany's proprietary clinical development pipeline specifically addresses innovative treatments for IBD, such as ulce
'"/>




Page: 1 2

Related medicine technology :

1. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
2. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
3. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
4. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
5. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
6. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
7. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
8. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
9. Cyclacel Pharmaceuticals Announces Results of Phase II Seliciclib Combination Studies
10. Arisaph Pharmaceuticals Announces Results of its Potent Smart DPP-4 Inhibitor, ARI-2243, at the ADA
11. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
Post Your Comments:
(Date:7/10/2014)... JORDAN, Utah , July 10, 2014  BC ... solutions, and MiE America , Inc., a leading ... have entered into a long-term agreement naming BC Technical ... the US. MiE and BC Technical ... strategic agreement to establish BC Technical as the service ...
(Date:7/10/2014)... -- CVS Caremark Corporation (NYSE: CVS ) today ... dividend of $0.275 (27.5 cents) per share on the corporation,s ... to holders of record on July 21, 2014. ... to helping people on their path to better health as ... States . Through the company,s more than 7,600 CVS/pharmacy ...
(Date:1/15/2014)... DUBLIN , Jan. 15, 2014  Research and Markets ... "Dental Consumables Market - Global Industry Analysis, Size, ... report to their offering. (Logo: ... products which are used on patients in order to ...
Breaking Medicine Technology:BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3
... SUNNYVALE, Calif. , June 3 Accuray ... the field of radiosurgery, today announced the installation of the ... of its acceptance as the world,s leading device for radiosurgery. ... in the United Kingdom , the first hospital operated ...
... , June 3 Perrigo Company (Nasdaq: PRGO ... the U.S. Food and Drug Administration for its abbreviated new drug ... generic to Monistat® -1 Combination Pack. Perrigo expects to begin shipping ... , ...
Cached Medicine Technology:Accuray Installs 200th CyberKnife Robotic Radiosurgery System 2Accuray Installs 200th CyberKnife Robotic Radiosurgery System 3Accuray Installs 200th CyberKnife Robotic Radiosurgery System 4Accuray Installs 200th CyberKnife Robotic Radiosurgery System 5Perrigo Announces FDA Final Approval for Miconazole 2Perrigo Announces FDA Final Approval for Miconazole 3
(Date:7/11/2014)... Europe is one of the largest ... hence, irrigated land area. The agricultural sector is a ... around 30.0% of the total water use. The scale ... southern region, but far from negligible in most northern ... over 60.0% of the water use in most countries, ...
(Date:7/11/2014)... are insoluble colorants, which usually consist of inorganic compounds. ... and coloring. These are water and oil insoluble natural ... as paper, paints, plastics, and concrete. Binders are used ... to the substance. Some examples of pigments are titanium ... coloring action of pigments is due to the scattering ...
(Date:7/11/2014)... best available treatment for patients, from a range of ... taxpayers than the existing clinical trial process, a new ... out while he was a member of the Clinical ... at The University of Manchester,s Health eResearch Centre, published ... today (Friday 11 July) looked at the use of ...
(Date:7/11/2014)... (PRWEB) July 11, 2014 Experience Mayan ... Mayan Heritage Experience Package at the luxury all-inclusive AAA ... package include a guided on-site ecological family tour where ... as The Coba Mayan Encounter Tour at the Mayan ... Muul, the tallest pyramid in the Yucatan and the ...
(Date:7/11/2014)... 2014 WWTrek Human Outreach Project ... Community in Tanzania. Opened in 2012, the KKC is now ... cows. HOP Founder, Dean Cardinale, started the KKC to create ... orphaned children he encountered while running treks on Tanzania's Mount ... who have all made astounding progress in school over the ...
Breaking Medicine News(10 mins):Health News:Europe Micro Irrigation System Market Driven by Growing Environmental Concerns and Decreasing Water Availability - New Report by MicroMarket Monitor 2Health News:Europe Micro Irrigation System Market Driven by Growing Environmental Concerns and Decreasing Water Availability - New Report by MicroMarket Monitor 3Health News:Americas Pigments Market Worth 1,099 Thousand MT by 2018 - New Report by MicroMarket Monitor 2Health News:Americas Pigments Market Worth 1,099 Thousand MT by 2018 - New Report by MicroMarket Monitor 3Health News:Better use of electronic health records makes clinical trials less expensive 2Health News:Explore the Aura and Mystery of the Yucatan’s Mayan Culture with New Hotel Package at AAA Five Diamond Grand Velas Riviera Maya 2Health News:Explore the Aura and Mystery of the Yucatan’s Mayan Culture with New Hotel Package at AAA Five Diamond Grand Velas Riviera Maya 3Health News:Human Outreach Project Sees Incredible Progress in the Kilimanjaro Kids Community 2
... scientists, led by researchers at the University of California, San ... for a condition in which eye and brain development is ... potential remedy that would involve a simple, daily dietary supplement. ... of glycosylation or CDG, a group of syndromes in which ...
... By Amanda Gardner HealthDay Reporter , WEDNESDAY, ... does raise the risk of heart attack more than other ... with tightened controls, a U.S. government advisory panel recommended late ... panel of experts rejected the option that the U.S. Food ...
... from the American Cancer Society and other world-leading health ... whose potential to cause cancer is as yet unresolved. ... research, and to lead to well-planned epidemiologic or mechanistic ... The report, "Identification of research needs to resolve ...
... University researchers and African colleagues will be studying strategies ... and environmental health. The work in regions where the ... a $2.2 million, four-year grant from the U.S. National ... 24 villages in the Mvomero district of Tanzania to ...
... Winston Salem, N.C. New research accepted by the ... developed at Wake Forest University will slash years off the ... treatments to patients much more quickly. Lab-on-Bead uses ... a disease marker in a single step, so researchers can ...
... fight as soldiers in 86 countries across the globe, ... explored how these children adjust after they return to ... was the characteristics of the communities to which the ... that former child soldiers from Sierra Leone who lived ...
Cached Medicine News:Health News:UC San Diego researchers find cause of metabolic disease -- and possible cure 2Health News:UC San Diego researchers find cause of metabolic disease -- and possible cure 3Health News:Avandia Raises Heart Risk But Should Stay on Market, FDA Panel Finds 2Health News:Avandia Raises Heart Risk But Should Stay on Market, FDA Panel Finds 3Health News:Avandia Raises Heart Risk But Should Stay on Market, FDA Panel Finds 4Health News:Report outlines knowledge gaps for 20 suspected carcinogens 2Health News:Duke and African partners to study sustainable malaria control 2Health News:Researchers cut years from drug development with nanoscopic bead technology 2Health News:Studies explore effects of war on former child soldiers 2Health News:Studies explore effects of war on former child soldiers 3Health News:Studies explore effects of war on former child soldiers 4
A budget-priced microscope designed for ENT and neuro surgery....
... has pioneered the development of ... system, an innovative solution that ... efficient and less invasive. The ... the OME-7000 surgical microscope, the ...
... Leica M501 TTS offers the comfort of ... and training application. The microscope offers brilliant ... stereopsis and natural color reproduction. A separate ... can be optimized with a special jalousie ...
The Leica M500 OH3 is an advanced surgical microscope used by neurosurgeons. It is a smart system combining the best optical performance available on the market with an innovative and unique stand....
Medicine Products: