Navigation Links
Conor Medsystems, LLC Reports COSTAR II Pivotal Drug-Eluting Stent,Trial Conclusions

MENLO PARK, Calif., May 07, 2007 /PRNewswire-FirstCall/ -- Citing issues related to potentially sub-optimal therapeutic dosing of paclitaxel, Conor Medsystems, LLC has concluded that the COSTAR II (CObalt Chromium STent with Antiproliferative for Restenosis) trial, the pivotal study for the CoStar cobalt chromium paclitaxel-eluting coronary stent, failed to meet its primary endpoint. The trial did not identify safety issues, and the overall rates of death, myocardial infarction and stent thrombosis were consistent with those observed in other clinically relevant drug-eluting stent studies.

As a result of these outcomes, the company will terminate ongoing clinical trials with the CoStar(R) stent and will not conclude the submission of its Pre-Market Approval application to the U.S. Food and Drug Administration for the product. Further, Conor Medsystems will discontinue sale of the product through commercial partners in certain countries in Europe, Asia and Latin America where the CoStar stent is already approved, and will work with those partners to facilitate return of product in inventory in customer accounts.

The COSTAR II trial compared the CoStar(R) stent with the Taxus Express(2) paclitaxel drug-eluting stent, and was designed to demonstrate non-inferiority at eight-month follow-up with respect to major adverse cardiac events (MACE) in patients with multi-vessel or single-vessel disease. In this trial, MACE was defined as a composite of clinically driven target vessel revascularization, heart attack (new myocardial infarction) related to the target vessel and cardiac death related to an intervened vessel.

"While we are disappointed in these results, we remain optimistic about the ability of the novel Conor Medsystems reservoir platform to provide precise and controlled delivery of a therapeutic agent based on earlier proof of concept testing and trials," said Campbell Rogers, M.D., chi
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Corgenix Reports New Clinical Data Correlating AtherOx Technology With Vascular Disease
2. Cobalis Reports Phase III Trial Results for PreHistin in Seasonal Allergic Rhinitis
3. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
4. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
5. Cytokinetics Reports Additional Clinical Trials Data for Ispinesib
6. The European Myeloma Platform Reports New Survival data for Revlimid Presented at the International Myeloma Workshop in Greece
7. Cytochroma Reports Positive Phase I Clinical Data for CTA018 Injection
8. Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension
9. Columbia Laboratories Reports Positive Results from Multi-dose Pharmacokinetic Study of Vaginally-administered Lidocaine
10. CytRx Reports Promising Data from Its Open-Label Extension Clinical Trial of Arimoclomol in ALS
11. Affymax Reports Phase 2 Clinical Dose Ranging Results of Once-Per-Month Hematide for the Treatment of Anemia
Post Your Comments:
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... the "Electrocardiogram (ECG) Devices - Global Trends, Estimates ... http://photos.prnewswire.com/prnh/20130307/600769 Global ... million by 2016. The North America ... market share while Europe claims ...
(Date:12/15/2014)... , December 15, 2014 BerGenBio ... for aggressive drug resistant cancers, today announces that it ... private placing from new and existing investors. ... support the development of its pipeline of innovative cancer ... its lead drug candidate, BGB324, a first-in-class selective Axl ...
(Date:12/15/2014)... and BRIDGEWATER, N.J. , Dec. ... and Sanofi US (EURONEXT: SAN and NYSE: SNY) are ... to launch Cholesterol Counts , an awareness program ... their numbers, and the risks associated with high LDL-C ... www. CholesterolCounts .com to take a brief poll ...
Breaking Medicine Technology:Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4BerGenBio Completes NOK90 Million Fundraising 2Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 2Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 3Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 4Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 5Have You Been Counted? Regeneron and Sanofi US Join Forces with Leading Cardiovascular Organizations to Raise Awareness of Cholesterol 6
... 1 Reproductive Partners Medical Group, Inc. announces their ... a financial incentive for patients with good embryo quality ... the chance of twins by transferring a single embryo. ... is reducing the number of multiple pregnancies, even twin ...
... , ... ), a leading online retailer of health, beauty, vision, and ... day ever as customer orders were the highest in company ... Beauty.com web stores featured more special offers than in ...
Cached Medicine Technology:Reproductive Partners Announces Elective Single Embryo Transfer (eSET) Encouragement Program 2drugstore.com, inc. Has Best Day Ever on Cyber Monday 2drugstore.com, inc. Has Best Day Ever on Cyber Monday 3
(Date:12/17/2014)... HealthDay Reporter TUESDAY, Dec. ... fast approaching, a new study reveals that states that routinely ... drunk drivers on their roads. The finding suggests that ... able to deter inebriated revelers from getting behind the wheel ... being passed regarding drinking and driving," said study lead author ...
(Date:12/15/2014)... 2014 Cancer researchers have just published ... causes of deadly malignant pleural mesothelioma. Surviving Mesothelioma has ... website. Click here to read it now. ... Cancer Center, and New York’s Langone Medical Center performed ... patients in an effort to pinpoint the genes ...
(Date:12/15/2014)... (PRWEB) December 15, 2014 SIMpalm, a ... “Winematch Connect App” for iPhone for its client, which ... WineMatch is a company, specialized in finding the right ... high-technology engine that uses combined sensory, chemistry and wine ... create a virtual “wine fingerprint.” Those wines that are ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 In support of ... attention to restrictive state laws that may have ... this important area of public health policy. , ... the Integrity of Independent Review, contends that state ... independent peer review determinations can result in subpar ...
Breaking Medicine News(10 mins):Health News:Enforcement of Drunk Driving Laws Makes Roads Safer, Study Finds 2Health News:Enforcement of Drunk Driving Laws Makes Roads Safer, Study Finds 3Health News:New Study Reveals Genetic Mutations That May Trigger Mesothelioma, According to Surviving Mesothelioma 2Health News:Use WinMatch Connect App to Keep Track of Wines You Like 2Health News:Study Shows Why Expert Pilots Are Experts 2Health News:NAIRO Calls for Higher Quality Independent Peer Review By Ending Restrictive State Laws 2
... plastic surgeon, Dr. Michael Niccole says there are plenty of ways ... time to research and do the homework before jumping into a ... ... March 25, 2009 -- Adapting one,s priorities to today,s changed economy ...
... and LOS ANGELES, March 25 AmeriCares, a nonprofit ... than $1.4 million worth of lifesaving medicines and medical ... Darfur refugees in Chad. The medical aid will ... from serious injuries, infections, diarrhea and chronic diseases, in ...
... Ind., March 25 OBS Medical has entered ... of London-based insurer of medical malpractice for US ... a reduced cost to hospitals that implement OBS,s ... of clinical crises.Recognized by Frost and Sullivan as ...
... to weaknesses in the U.S. economy, plastic surgery ... to the newest national procedural statistics report from ... 2008, doctors performed over 12 million cosmetic plastic ... procedures. Surgical numbers dropped nine percent and minimally-invasive ...
... ULU) today announced that it has scheduled a ... 2008 financial results and provide a general business update on ... in the conference call please dial (800) 357-0498, for international ... minutes prior to the initiation of the teleconference. If ...
... official IRS determination letter. , ... New York, NY (Vocus) March 25, ... receipt of their official IRS determination letter. This letter confirms Angie,s Spa ... spa services for cancer patients undergoing chemotherapy. , , ,Thanks ...
Cached Medicine News:Health News:Orange County Plastic Surgeon Warns: When It Comes To The Face And Body, The Best Deal Could Cost More 2Health News:AmeriCares and International Medical Corps Partner to Bring Lifesaving Aid to Chad 2Health News:OBS Medical's Visensia Patient Monitoring Technology Lowers Cost of Medical Malpractice Insurance 2Health News:Recession cuts many, not all plastic surgery procedures 2Health News:ULURU Inc. Announces Conference Call to Discuss Financial Results for the Fourth Quarter and Year Ended December 31, 2008 and to Provide a Business Update 2Health News:Angie's Spa Receives Official Acknowledgment of Non-Profit Status 2
... Packed conveniently in plastic-wrapped racks of 96 ... useno need to autoclave. Sterilized Diamond Tips ... sterilization and are delivered with a certificate ... Sterilized Diamond Tips are certified free of ...
... Finntips have been designed to optimize the ... of our tip products is widely recognized ... range has been extended over the years ... standard and special tips including filter tips, ...
This large orifice 1000 ul tips is the large volume alternative to MBP's 200G tip. Pipet fragile cells, viscous samples and genomic DNA with ease....
... to optimize the accuracy and precision of ... is widely recognized by customers throughout the ... over the years and now covers a ... including filter tips, certified pure tips, stepper ...
Medicine Products: